Improvement of rejection-induced diastolic abnormalities in rat cardiac allografts with inducible nitric oxide synthase inhibition

Journal of Thoracic and Cardiovascular Surgery

Volumn 120, Issue 1, 2000, Pages 39-46

  Soto, Pablo F ^a   Jia, Chao Xiang ^c   Rabkin, David G ^c   Hart, Joseph P ^c   Carter, Yvonne M ^b   Sardo, Michael J ^c   Hsu, Daphne T ^c   Fisher, Peter E ^c   Pinsky, David J ^c   Spotnitz, Henry M ^c  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c New York Presbyterian Columbia University Medical Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOGUANIDINE; DEXAMETHASONE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; GRAFT REJECTION; HEART EDEMA; HEART LEFT VENTRICLE FILLING; HEART TRANSPLANTATION; NONHUMAN; PRIORITY JOURNAL; RAT; XENOTRANSPLANTATION;

EID: 0034235027     PISSN: 00225223     EISSN: None     Source Type: Journal    
DOI: 10.1067/mtc.2000.107124     Document Type: Article

References (20)

1. Worrall N.K., Chang K., Suau G.M., Allison W.S., Misko T.P., Sullivan P.M. Inhibition of inducible nitric oxide synthase prevents myocardial and systemic vascular barrier dysfunction during early cardiac allograft rejection. Circ Res. 78:1996;769-779.
2. Worrall N.K., Pyo R.T., Botney M.D., Misko T.P., Sullivan P.M., Alexander D.G. Inflammatory cell-derived NO modulates cardiac allograft contractile and electrophysiological function. Am J Physiol. 273:1997;H28-37.
3. Worrall N.K., Misko T.P., Botney M.D., Sullivan P.M., Hui J.J., Suau G.M. Time course and cellular localization of inducible nitric oxide synthases expression during cardiac allograft rejection. Ann Thorac Surg. 67:1999;716-722.
4. Cai B., Roy D.K., Sciacca R., Michler R.E., Cannon P.J. Effects of immunosuppressive therapy on expression of inducible nitric oxide synthase (NOS II) during cardiac allograft rejection. Int J Cardiol. 50:1995;243-251.
5. Worrall N.K., Lazenby W.D., Misko T.P., Lin T.S., Rodi R.P., Manning P.T. Modulation of in vivo alloreactivity by inhibition of inducible nitric oxide synthase. J Exp Med. 181:1995;63-70.
6. Amirhamzeh M.M.R., Jia C., Starr J.P., Sciacca R., Chowdhury N.C., Hsu D.T. Diastolic function in the heterotopic rat heart transplant model: effects of edema, ischemia, and rejection. J Thorac Cardiovasc Surg. 108:1994;928-937.
7. Carter Y.M., Jia C., Soto P.F., Starr J.P., Rabkin D.G., Hsu D.T. Diastolic properties, myocardial water content and histologic condition of the rat left ventricle: effect of varied osmolarity of a coronary perfusate. J Heart Lung Transplant. 17:1998;140-149.
8. Soto P.F., Jia C., Carter Y.M., Rabkin D., Starr J.P., Amirhamzeh M.M. Effect of improved myocardial protection on edema and diastolic properties of the rat left ventricle during acute allograft rejection. J Heart Lung Transplant. 17:1998;608-616.
9. Ono K., Lindsey E.S. Improved technique of heart transplantation in rats. J Thorac Cardiovasc Surg. 7:1969;225-229.
10. Zeballos G.A., Bernstein R.D., Thompson C.I., Forfia P.R., Seyedi N., Shen W. Pharmacodynamics of plasma nitrate/nitrite as an indication of nitric oxide formation in conscious dogs. Circulation. 91:1995;2982-2988.
11. Billingham M.E., Cary N.R., Hammond M.E., Kemnitz J., Marboe C., McCallister H.A. A working formulation for standardization of nomenclature in the diagnosis of heart and lung rejection: heart rejection study group. J Heart Transplant. 9:1990;587-593.
12. Yuan Y., Granger H.J., Zawieja D.C., DeFily D.V., Chilian W.M. Histamine increases venular permeability via a phospholipase C-NO synthase-guanylate cyclase cascade. Am J Physiol. 264:1993;H1734-9.
13. Yang X., Chowdhury N., Cai B., Brett J., Marboe C. Induction of myocardial nitric oxide synthase by cardiac allograft rejection. J Clin Invest. 94:1994;714-721.
14. Pinsky D.J., Cai B., Yang X., Rodriguez C., Sciacca R.R., Cannon D.J. The lethal effects of cytokine-induced nitric oxide on cardiac myocytes are blocked by nitric oxide synthase antagonism of transforming factor beta. J Clin Invest. 95:1995;671-685.
15. Pinsky D.J., Patton S., Mesaros S., Brovkovych V., Kubaszewski E., Grunfeld S. Mechanical transduction of nitric oxide synthesis in the beating heart. Circ Res. 81:1997;372-379.
16. Mason R., Anning P., Evans H., Lewis M.J., Shah A.M. Modulation of left ventricular relaxation in isolated ejecting heart by endogenous nitric oxide. Am J Physiol. 1994;267.
17. Lewis N.P., Tsao P.S., Rickenbache P.R., Xue C., Johns R.A., Haywood G.A. Induction of nitric oxide synthase in the human cardiac allograft is associated with contractile dysfunction of the left ventricle. Circulation. 93:1996;720-729.
18. Schwartz D., Mendonca M., Schwartz I., Xia Y., Satriano J., Wilson C.B. Inhibition of constitutive nitric oxide synthase (NOS) by nitric oxide generated by inducible NOS after lipopolysaccharide administration provokes renal dysfunction in rats. J Clin Invest. 100:1997;439-448.
19. Starr J.P., Jia C.X., Rabkin D.G., Amirhamzeh M.M., Hart J.P., Hsu D.T. Pressure volume curves in arrested heterotopic rat heart isografts: role of improved myocardial protection. J Surg Res. 86:1999;123-129.
20. Pinsky D.J., Aji W., Szabolcs M., Athan E.S., Liu Y., Yang Y.M. Nitric oxide triggers programmed cell death (apoptosis) of adult rat ventricular myocytes in culture. Am J Physiol. 1999;277.