Sensory stimulation increases cortical expression of the fragile X mental retardation protein in vivo

Molecular Brain Research

Volumn 80, Issue 1, 2000, Pages 17-25

  Todd, Peter K ^a   Mack, Kenneth J ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Calcineurin; Developmental disorders; Disorders of the nervous system; Experience dependent plasticity; Fragile X mental retardation protein; Fragile X syndrome; Kainic acid; Seizures

Indexed keywords

CALCINEURIN; KAINIC ACID; PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FRAGILE X SYNDROME; IMMUNOBLOTTING; MALE; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEIZURE; SENSORIMOTOR CORTEX; SENSORY STIMULATION; SYNAPTOSOME;

ANIMALS; CALCINEURIN; FRAGILE X MENTAL RETARDATION PROTEIN; FRAGILE X SYNDROME; KAINIC ACID; MALE; MENTAL RETARDATION; NERVE TISSUE PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; RNA-BINDING PROTEINS; SEIZURES; SENSORY THRESHOLDS; SOMATOSENSORY CORTEX;

EID: 0034233934     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(00)00098-X     Document Type: Article

References (37)

1. Ashley C.T., Wilkinson K.D., Reines D., Warren S.T. FMR-1 protein: conserved RNP family domains and selective RNA binding. Science. 262:1993;563-566.
2. Comery T.A., Harris J.B., Willems P.J., Oostra B.A., Irwin S.A., Weiler I.J., Greenough W.T. Abnormal dendritic spines in fragile X knockout mice: maturation and pruning deficits. Proc. Natl. Acad. Sci. USA. 94:1997;5401-5404.
3. De Vries B.B.A., Halley D.J.J., Oostra B.A., Niermeijer M.F. The fragile X syndrome. J. Med. Genet. 35:1998;579-589.
4. Devys D., Lutz Y., Rouyer N., Bellocq J.-P., Mandel J.-L. The FMR-1 protein is cytoplasmic, most abundant in neurons and appears normal in carriers of a fragile X premutation. Nature Genet. 4:1993;335-340.
5. FMR-1 knockout mice: a model to study fragile X mental retardation. Cell. 78:1994;23-30.
6. Eberhart D.E., Malter H.E., Feng Y., Warren S.T. The fragile X mental retardation protein is a ribonucleoprotein containing both nuclear localization and nuclear export signals. Hum. Mol. Genet. 5:(8):1996;1083-1091.
7. Eberhart D.E., Warren S.T. The molecular basis of fragile X syndrome. Cold Spring Harbor Symposia on Quantitative Biology. 61:1996;679-687.
8. Feng Y., Gutekunst C., Eberhart D.E., Hong Y., Warren S.T., Hersch S.M. Fragile X mental retardation protein: Neucleocytoplasmic shuttling and association with somatodendritic ribosomes. J. Neurosci. 17:(5):1997;1539-1547.
9. Feng Y., Absher D., Eberhart D.E., Brown V., Malter H.E., Warren S.T. FMRP associates with polyribosomes as an mRNP and the I304N mutation of severe fragile X syndrome abolishes this association. Mol. Cell. 1:1997;109-118.
10. Godfraind J.-M., Reyniers E., Deboulle K., D' Hooge R., De Deyn P.P., Bakker C.E., Oostra B.A., Kooy R.F., Willems P.J. Long term potentiation in the hippocampus of fragile X knockout mice. Am. J. Med. Genet. 64:1996;246-251.
11. Hendry S.H.C., Jones E.G. Activity dependent regulation of GABA expression in the visual cortex of adult monkeys. Neuron. 1:1988;701-712.
12. Herdegen T., Leah J.D. Inducible and constitutive transcription factors in the mammalian nervous system: control of gene expression by jun, fos, and krox, and CREB/ATF proteins. Brain Res. Rev. 28:1998;370-490.
13. Hinton V.J., Brown W.T., Wisniewski K., Rudelli R.D. Analysis of neocortex in three males with fragile X syndrome. Am. J. Med. Genet. 41:1991;289-294.
14. Huttner W.B., Schiebler W., Greengard P., de Camilli P. Synapsin I (protein 1), a nerve terminal specific phosphoprotein. III. Its association with synaptic vesicles studied in a highly purified synaptic vesicle preparation. J. Cell Biol. 96:1983;1374-1388.
15. Irwin S.A., Swain R.A., Christmon C.A., Chakravarti A., Weiler I.J., Greenough W.T. Evidence for altered Fragile-X mental retardation protein expression in response to behavioral stimulation. Neurobiol. Learning Memory. 73:2000;87-93.
16. Lynch M.W., Rutecki P.A., Sutula T.P. The effects of seizures on the brain. Curr. Opin. Neurol. 9:1996;97-102.
17. J Mack K., Mack P.A. Induction of transcription factors in somatosensory cortex after tactile stimulation. Brain Res. 12:1992;141-147.
18. Mack K.J., Yi S.D., Chang S., Millan N., Mack P. NGFI-C expression is effected by physiological stimulation and seizures in the somatosensory cortex. Mol. Brain Res. 29:1995;140-146.
19. Maggi C.A., Meli A. Suitability of urethane anethesia for physiopharmacological investigations in various systems. I. general considerations. Experimentia. 42:1986;109-210.
20. Mansuy I.M., Mayford M., Jacob B., Kandel E.R., Bach M.E. Restricted and regulated overexpression reveals calcineurin as a key component in the transition from short-term to long-term memory. Cell. 92:1998;39-49.
21. Mulkey R.M., Endo S., Shenolikar S., Malenka R.C. Involvement of a calcineurin/inhibitor-1 phosphatase cascade in hippocampal long-term depression. Nature. 369:1994;486-488.
22. Nanda S.A., J Mack K. Multiple promoters direct stimulus and temporal specific expression of brain derived neurotrophic factor in the somatosensory cortex. Molec. Brain Res. 62:1998;216-219.
23. Oberle I., Rousseau F., Heitz D., Kretz C., Devys D., Hanauer A., Boue J., Bertheas M.F., Mandel J.-L. Instability of a 550-base pair DNA segment and abnormal methylation in fragile X syndrome. Science. 252:1991;1097-1102.
24. Rudelli R.D., Brown W.T., Wisniewski K., et al. Adult fragile X syndrome. Clinico-neuropathological findings. Acta Neuropath. 67:1985;289-295.
25. Siomi H., Siomi M.C., L Nussbaum R., Dreyfuss G. The protein product of the fragile X gene FMR-1 has characteristics of an RNA binding protein. Cell. 74:1993;291-298.
26. Sola C., Tusell J.M., Serretosa J. Decreased expression of calcium calmodulin dependent kinase II and calcineurin mRNAs in the mouse hippocampus after kainic acid induced seizures. J. Neurochem. 70:1998;1600-1608.
27. Tamanini F., Meijer N., Verheij C., Willems P.J., Galjaard H., Oostra B.A., Hoogeveen A.T. FMRP is associated to the ribosomes via RNA. Hum. Mol. Genet. 5:(6):1996;809-813.
28. Tamanini F., Bontekoe C., Bakkar C.E., van Unen L., Anar B., Willemsen R., Yoshida M., Galjaard H., Oostra B.A., Hoogeveen A.T. Different targets for the fragile X related proteins revealed by distinct nuclear localizations. Hum. Mol. Genet. 8:(6):1999;863-869.
29. Turner G., Webb T., Wake S., Robinson H. Prevalence of fragile X syndrome. Am. J. Med. Genet. 64:1996;196-197.
30. Verheij C., Bakkar C.E., de Graaff E., Kleulemans J., Willemsen R., Verkerk A.J.M.H., Galjaard H., Reuser A.J.J., Hoogeveen A.T., Oostra B.A. Characterization and localization of the FMR-1 gene product associated with fragile X syndrome. Nature. 363:1993;722-724.
31. Verkerk A.J.M.H., Piertti M., Sutcliffe J.S., Fu Y.-H., Kuhl D.P.A., Pizutti A., Reiner O., Richards S., Victoria M.F., Zhang F., Eussen B.E., van Ommen G.J.B., Blonden L.A.J., Riggins G.J., Chastain J.L., Kunst C.B., Galjaard H., Caskey C.T., Nelson D.L., Oostra B.A., Warren S.T. Identification of a gene (fmr-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome. Cell. 65:1991;905-914.
32. Weiler I.J., Irwin S.A., Klintsova A.Y., Spencer C.M., Brazelton A.D., Miyashiro K., Comery T.A., Patel B., Eberwine J., Greenough W.T. Fragile X mental retardation protein is translated near synapses in response to neurotransmitter activation. Proc. Natl. Acad. Sci. USA. 94:1997;5395-5400.
33. Welker, E., Soriano, J. Dorlf, H. Vanderloos, Plasticity in the barrel cortex of the adult mouse transient increase of GAD immunoreativity following sensory stimulation, Exp. Brain Res., 78 (1989) 659-664.
34. Winder D.G., Mansuy I.M., Osman M., Moallem T.M., Kandel E.R. Genetic and pharmacological evidence for a novel, intermediate phase of long term potentiation suppressed by calcineurin. Cell. 92:1998;25-37.
35. Wisniewski K.E., Segan S.M., Miezejeski C.M., Sersen E.A., Rudelli R.D. The fragile X syndrome: neurological, electrophysiological, and neuropathological abnormalities. Am. J. Med. Genet. 38:1991;476-480.
36. Yakel J. Calcineurin regulation of synaptic function: from ion channels to transmitter release and gene transcription. Trends Pharm. Sci. 18:1997;124-134.
37. Yu S., Prichard M., Kremer E., Lynch M., Nancarrow J., Baker E., Holman K., Mulley J.C., Warren S.T., Schlesinger D., Sutherland G.R., Richards R.I. Fragile X genotype characterized by an unstable region of DNA. Science. 252:1991;1179-1181.