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Volumn 71, Issue 7, 2000, Pages 1079-1085

Collagen fibers and inflammatory cells in healthy and diseased human gingival tissues: A comparative and quantitative study by immunohistochemistry and automated imaqe analysis

Author keywords

Cells, cytotoxic; Cells, inflammatory; Collagen; Periodontal diseases diagnosis; Periodontal diseases pathogenesis

Indexed keywords

COLLAGEN; EPITOPE;

EID: 0034220652     PISSN: 00223492     EISSN: None     Source Type: Journal    
DOI: 10.1902/jop.2000.71.7.1079     Document Type: Article
Times cited : (60)

References (50)
  • 1
    • 84987589352 scopus 로고
    • Pathogenesis of periodontitis
    • Listgarten MA. Pathogenesis of periodontitis. J Clin Periodontol 1986;13:418-425.
    • (1986) J Clin Periodontol , vol.13 , pp. 418-425
    • Listgarten, M.A.1
  • 2
    • 0024729857 scopus 로고
    • Infections and periodontal diseases
    • Hirsch RS, Clarke NG. Infections and periodontal diseases. Rev Infect Dis 1989;11:707-715.
    • (1989) Rev Infect Dis , vol.11 , pp. 707-715
    • Hirsch, R.S.1    Clarke, N.G.2
  • 3
    • 0017275766 scopus 로고
    • Pathogenesis of inflammatory periodontal disease. A summary of current work
    • Page RC, Schroeder HE. Pathogenesis of inflammatory periodontal disease. A summary of current work. Lab Invest 1976;34:235-249.
    • (1976) Lab Invest , vol.34 , pp. 235-249
    • Page, R.C.1    Schroeder, H.E.2
  • 5
    • 0030093911 scopus 로고    scopus 로고
    • Diagnostic strategies of periodontitis based on the molecular mechanisms of periodontal tissue destruction
    • Okada H, Murakami S, Kitamura M, et al. Diagnostic strategies of periodontitis based on the molecular mechanisms of periodontal tissue destruction. Oral Dis 1996;2:87-95.
    • (1996) Oral Dis , vol.2 , pp. 87-95
    • Okada, H.1    Murakami, S.2    Kitamura, M.3
  • 6
    • 0029141399 scopus 로고
    • Evidence of a direct relationship between neutrophil collagenase activity and periodontal tissue destruction in vivo: Role of active enzyme in human periodontitis
    • Lee W, Aitken S, Sodek J, McCulloch CA. Evidence of a direct relationship between neutrophil collagenase activity and periodontal tissue destruction in vivo: Role of active enzyme in human periodontitis. J Periodont Res 1995;30:23-33.
    • (1995) J Periodont Res , vol.30 , pp. 23-33
    • Lee, W.1    Aitken, S.2    Sodek, J.3    McCulloch, C.A.4
  • 7
    • 0028391312 scopus 로고
    • Immunolocalization of matrix metalloproteinases and TIMP-1 (tissue inhibitor of metalloproteinases) in human gingival tissues from periodontitis patients
    • Meikle MC, Hembry RM, Holley J, Norton C, McFarlane CG, Reynolds JJ. Immunolocalization of matrix metalloproteinases and TIMP-1 (tissue inhibitor of metalloproteinases) in human gingival tissues from periodontitis patients. J Periodont Res 1994;29:118-126.
    • (1994) J Periodont Res , vol.29 , pp. 118-126
    • Meikle, M.C.1    Hembry, R.M.2    Holley, J.3    Norton, C.4    McFarlane, C.G.5    Reynolds, J.J.6
  • 8
    • 0032574438 scopus 로고    scopus 로고
    • Advances in periodontal diagnosis. 6. Proteolytic and hydrolytic enzymes of inflammatory cell origin
    • Eley BM, Cox SW. Advances in periodontal diagnosis. 6. Proteolytic and hydrolytic enzymes of inflammatory cell origin. Br Dent J 1998;184:268-271.
    • (1998) Br Dent J , vol.184 , pp. 268-271
    • Eley, B.M.1    Cox, S.W.2
  • 9
    • 0028309211 scopus 로고
    • The role of cytokines in the pathogenesis of periodontal disease
    • Alexander MB, Damoulis PD. The role of cytokines in the pathogenesis of periodontal disease. Curr Opin Periodontol 1994;2:39-53.
    • (1994) Curr Opin Periodontol , vol.2 , pp. 39-53
    • Alexander, M.B.1    Damoulis, P.D.2
  • 10
    • 0029445346 scopus 로고
    • Cytokine networks in destructive periodontal disease
    • Howells GL. Cytokine networks in destructive periodontal disease. Oral Dis 1995;1:266-270.
    • (1995) Oral Dis , vol.1 , pp. 266-270
    • Howells, G.L.1
  • 11
    • 0031908674 scopus 로고    scopus 로고
    • IL-1 and TNF antagonists inhibit the inflammatory response and bone loss in experimental periodontitis
    • Assuma R, Oates T, Cochran DL, Amar S, Graves DT. IL-1 and TNF antagonists inhibit the inflammatory response and bone loss in experimental periodontitis. J Immunol 1998;160:403-409.
    • (1998) J Immunol , vol.160 , pp. 403-409
    • Assuma, R.1    Oates, T.2    Cochran, D.L.3    Amar, S.4    Graves, D.T.5
  • 12
    • 0028183693 scopus 로고
    • Interleukin 1β stimulates collagenase production by cultured human periodontal ligament fibroblasts
    • Ohshima M, Otsuka K, Suzuki K. Interleukin 1β stimulates collagenase production by cultured human periodontal ligament fibroblasts. J Periodont Res 1994; 29:421-429.
    • (1994) J Periodont Res , vol.29 , pp. 421-429
    • Ohshima, M.1    Otsuka, K.2    Suzuki, K.3
  • 13
    • 0029088590 scopus 로고
    • Growth factor effects on the expression of collagenase and TIMP-1 in periodontal ligament cells
    • Alvares O, Klebe R, Grant G, Cochran DL. Growth factor effects on the expression of collagenase and TIMP-1 in periodontal ligament cells. J Periodontol 1995; 66:552-558.
    • (1995) J Periodontol , vol.66 , pp. 552-558
    • Alvares, O.1    Klebe, R.2    Grant, G.3    Cochran, D.L.4
  • 14
    • 0031134623 scopus 로고    scopus 로고
    • Cytokines modulate routes of collagen breakdown. Review with special emphasis on mechanisms of collagen degradation in the periodontium and the burst hypothesis of periodontal disease progression
    • van der Zee E, Everts V, Beertsen W. Cytokines modulate routes of collagen breakdown. Review with special emphasis on mechanisms of collagen degradation in the periodontium and the burst hypothesis of periodontal disease progression. J Clin Periodontol 1997;24:297-305.
    • (1997) J Clin Periodontol , vol.24 , pp. 297-305
    • Van Der Zee, E.1    Everts, V.2    Beertsen, W.3
  • 15
    • 0030982717 scopus 로고    scopus 로고
    • Factors affecting IL-1 mediated collagen metabolism by fibroblasts and the pathogenesis of periodontal disease: A review of the literature
    • Havemose-Poulsen A, Holmstrup P. Factors affecting IL-1 mediated collagen metabolism by fibroblasts and the pathogenesis of periodontal disease: A review of the literature. Crit Rev Oral Biol Med 1997;8:217-236.
    • (1997) Crit Rev Oral Biol Med , vol.8 , pp. 217-236
    • Havemose-Poulsen, A.1    Holmstrup, P.2
  • 16
    • 0024528486 scopus 로고
    • Fibroblastic sub-populations in injured and wounded rabbit oral mucosa
    • Bronson RE, Treat JA, Bertolami CN. Fibroblastic sub-populations in injured and wounded rabbit oral mucosa. J Dent Res 1989;68:51-58.
    • (1989) J Dent Res , vol.68 , pp. 51-58
    • Bronson, R.E.1    Treat, J.A.2    Bertolami, C.N.3
  • 17
    • 0031152007 scopus 로고    scopus 로고
    • Mechanisms of connective tissue matrix destruction in periodontitis
    • Reynolds JJ, Meikle MC. Mechanisms of connective tissue matrix destruction in periodontitis. Periodontol 2000 1997;14:144-157.
    • (1997) Periodontol 2000 , vol.14 , pp. 144-157
    • Reynolds, J.J.1    Meikle, M.C.2
  • 18
    • 0033227311 scopus 로고    scopus 로고
    • Imunohistologic and morphometric analysis of cytotoxic T lymphocytes in gingivitis
    • Séguier S, Godeau G, Leborgne M, Pivert G, Brousse N. Imunohistologic and morphometric analysis of cytotoxic T lymphocytes in gingivitis. J Periodontol 1999; 70:1383-1391.
    • (1999) J Periodontol , vol.70 , pp. 1383-1391
    • Séguier, S.1    Godeau, G.2    Leborgne, M.3    Pivert, G.4    Brousse, N.5
  • 19
    • 0023392109 scopus 로고
    • Phenotypic and functional analysis of T cells extracted from chronically inflamed human periodontal tissues
    • Cole KL, Seymour GJ, Powell RN. Phenotypic and functional analysis of T cells extracted from chronically inflamed human periodontal tissues. J Periodontol 1987;58:569-573.
    • (1987) J Periodontol , vol.58 , pp. 569-573
    • Cole, K.L.1    Seymour, G.J.2    Powell, R.N.3
  • 20
    • 0026504636 scopus 로고
    • Distribution and phenotype of immune cells in normal human gingiva: Active immune response versus unresponsiveness
    • Colasante A, Rosini S, Piattelli A, Artese L, Aiello FB, Musiani P. Distribution and phenotype of immune cells in normal human gingiva: Active immune response versus unresponsiveness. J Oral Pathol Med 1992;21:12-16.
    • (1992) J Oral Pathol Med , vol.21 , pp. 12-16
    • Colasante, A.1    Rosini, S.2    Piattelli, A.3    Artese, L.4    Aiello, F.B.5    Musiani, P.6
  • 21
    • 0023245085 scopus 로고
    • Phenotypic analysis of mononuclear cells recovered from healthy and diseased periodontal tissues
    • Stouffi ED, Taubman MA, Ebersole JL, Smith DJ, Stashenko PP. Phenotypic analysis of mononuclear cells recovered from healthy and diseased periodontal tissues. J Clin Immunol 1987;7:235-245.
    • (1987) J Clin Immunol , vol.7 , pp. 235-245
    • Stouffi, E.D.1    Taubman, M.A.2    Ebersole, J.L.3    Smith, D.J.4    Stashenko, P.P.5
  • 23
    • 75549115165 scopus 로고
    • Periodontal disease in pregnancy. I. Prevalence and severity
    • Löe H, Silness J. Periodontal disease in pregnancy. I. Prevalence and severity. Acta Odontol Scand 1963;21: 533-551.
    • (1963) Acta Odontol Scand , vol.21 , pp. 533-551
    • Löe, H.1    Silness, J.2
  • 24
    • 0018775237 scopus 로고
    • Picrosirius staining plus polarization microscopy, a specific method for collagen detection in tissue sections
    • Junqueira LCU, Bignolas G, Brentani RR. Picrosirius staining plus polarization microscopy, a specific method for collagen detection in tissue sections. Histochem J 1979;11:447-455.
    • (1979) Histochem J , vol.11 , pp. 447-455
    • Junqueira, L.C.U.1    Bignolas, G.2    Brentani, R.R.3
  • 25
    • 0025015146 scopus 로고
    • A monoclonal antibody reactive with a 15-kDa cytoplasmic granule-associated protein defines a subpopulation of CD8+ T lymphocytes
    • Anderson P, Nagler Anderson C, O'Brien C. A monoclonal antibody reactive with a 15-kDa cytoplasmic granule-associated protein defines a subpopulation of CD8+ T lymphocytes. J Immunol 1990;144:574-582.
    • (1990) J Immunol , vol.144 , pp. 574-582
    • Anderson, P.1    Nagler Anderson, C.2    O'Brien, C.3
  • 26
    • 0026015364 scopus 로고
    • Expression of perforin and granzymes in vivo: Potential diagnostic markers for activated cytotoxic cells
    • Griffiths GM, Mueller C. Expression of perforin and granzymes in vivo: Potential diagnostic markers for activated cytotoxic cells. Immunol Today 1991;12:415-419.
    • (1991) Immunol Today , vol.12 , pp. 415-419
    • Griffiths, G.M.1    Mueller, C.2
  • 27
    • 0026334070 scopus 로고
    • The 5′-flanking region of the human CGl-1/granzyme B gene targets expression of a reporter gene to activated T-lymphocytes in transgenic mice
    • Hanson RD, Sclar GM, Kanagawa O, Ley TJ. The 5′-flanking region of the human CGL-1/granzyme B gene targets expression of a reporter gene to activated T-lymphocytes in transgenic mice. J Biol Chem 1991;266: 24433-24438.
    • (1991) J Biol Chem , vol.266 , pp. 24433-24438
    • Hanson, R.D.1    Sclar, G.M.2    Kanagawa, O.3    Ley, T.J.4
  • 28
    • 0019451604 scopus 로고
    • Suppression of endogenous avidin-binding activity in tissues and its relevance to biotin-avidin detection systems
    • Woods GS, Warnke R. Suppression of endogenous avidin-binding activity in tissues and its relevance to biotin-avidin detection systems. J Histochem Cytochem 1981;29:1196-1204.
    • (1981) J Histochem Cytochem , vol.29 , pp. 1196-1204
    • Woods, G.S.1    Warnke, R.2
  • 29
    • 0022838697 scopus 로고
    • A selective method for the quantitative estimation of elastic fibers by computerized morphometric analysis
    • Godeau G, Gonnord G, Jolivet O, et al. A selective method for the quantitative estimation of elastic fibers by computerized morphometric analysis. Anal Quant Cytol Histol 1986;4:321-325.
    • (1986) Anal Quant Cytol Histol , vol.4 , pp. 321-325
    • Godeau, G.1    Gonnord, G.2    Jolivet, O.3
  • 31
    • 0022596874 scopus 로고
    • Proteases and their inhibitors in chronic inflammatory periodontal disease
    • Sandholm L. Proteases and their inhibitors in chronic inflammatory periodontal disease. J Clin Periodontol 1986;13:19-26.
    • (1986) J Clin Periodontol , vol.13 , pp. 19-26
    • Sandholm, L.1
  • 32
    • 0030256311 scopus 로고    scopus 로고
    • Matrix metalloproteinases-1 and -8 and TIMP-1 mRNA levels in normal and diseased human gingivae
    • Aiba T, Akeno N, Kawane T, Okamoto H, Horiuchi N. Matrix metalloproteinases-1 and -8 and TIMP-1 mRNA levels in normal and diseased human gingivae. Eur J Oral Sci 1996;104:562-569.
    • (1996) Eur J Oral Sci , vol.104 , pp. 562-569
    • Aiba, T.1    Akeno, N.2    Kawane, T.3    Okamoto, H.4    Horiuchi, N.5
  • 33
    • 0028476829 scopus 로고
    • Connective tissue degradation in health and periodontal disease and the roles of matrix metalloproteinases and their natural inhibitors
    • Reynolds JJ, Hembry RM, Meikle MC. Connective tissue degradation in health and periodontal disease and the roles of matrix metalloproteinases and their natural inhibitors. Adv Dent Res 1994;8:312-319.
    • (1994) Adv Dent Res , vol.8 , pp. 312-319
    • Reynolds, J.J.1    Hembry, R.M.2    Meikle, M.C.3
  • 34
    • 0025847582 scopus 로고
    • Matrix proteinases and their inhibitors in connective tissue remodeling
    • Woessner JF. Matrix proteinases and their inhibitors in connective tissue remodeling. FASEB J 1991;5:2145-2154.
    • (1991) FASEB J , vol.5 , pp. 2145-2154
    • Woessner, J.F.1
  • 35
    • 0029150795 scopus 로고
    • Proteolytic remodeling of extracellular matrix
    • Birkedal-Hansen H. Proteolytic remodeling of extracellular matrix. Curr Opin Cell Biol 1995;7:718-735.
    • (1995) Curr Opin Cell Biol , vol.7 , pp. 718-735
    • Birkedal-Hansen, H.1
  • 36
    • 0029688549 scopus 로고    scopus 로고
    • Matrix metalloproteinases and their inhibition in periodontal treatment
    • Ryan ME, Ramamurthy S, Golub LM. Matrix metalloproteinases and their inhibition in periodontal treatment. Curr Opin Periodontol 1996;3:85-96.
    • (1996) Curr Opin Periodontol , vol.3 , pp. 85-96
    • Ryan, M.E.1    Ramamurthy, S.2    Golub, L.M.3
  • 37
    • 0028509288 scopus 로고
    • Collagenase activity and tissue inhibitor of metalloproteinases-1 (TIMP-1) content in human whole saliva from clinically healthy and periodontally diseased subjects
    • Hayakawa H, Yamashita K, Ohwaki K, et al. Collagenase activity and tissue inhibitor of metalloproteinases-1 (TIMP-1) content in human whole saliva from clinically healthy and periodontally diseased subjects. J Periodont Res 1994;29:305-308.
    • (1994) J Periodont Res , vol.29 , pp. 305-308
    • Hayakawa, H.1    Yamashita, K.2    Ohwaki, K.3
  • 38
    • 0030103118 scopus 로고    scopus 로고
    • Expression of mRNA for matrix metalloproteinases and tissue inhibitors of metalloproteinases in periodontitis-affected human gingival tissue
    • Kubota T, Nomura T, Takahashi T, Hara K. Expression of mRNA for matrix metalloproteinases and tissue inhibitors of metalloproteinases in periodontitis-affected human gingival tissue. Arch. Oral Biol 1996;41:253-262.
    • (1996) Arch. Oral Biol , vol.41 , pp. 253-262
    • Kubota, T.1    Nomura, T.2    Takahashi, T.3    Hara, K.4
  • 39
    • 0023301216 scopus 로고
    • Demonstration of tissue collagenase activity in vivo and its relationship to inflammation severity in human gingiva
    • Overall CM, Wiebkin OW, Thonard JC. Demonstration of tissue collagenase activity in vivo and its relationship to inflammation severity in human gingiva. J Periodont Res 1987;22:81-88.
    • (1987) J Periodont Res , vol.22 , pp. 81-88
    • Overall, C.M.1    Wiebkin, O.W.2    Thonard, J.C.3
  • 40
    • 0019515449 scopus 로고
    • Immunolocalization of collagenase in periodontal disease
    • Woolley DE, Davies RM. Immunolocalization of collagenase in periodontal disease. J Periodont Res 1981;16: 292-297.
    • (1981) J Periodont Res , vol.16 , pp. 292-297
    • Woolley, D.E.1    Davies, R.M.2
  • 41
    • 0031218929 scopus 로고    scopus 로고
    • Morphometric analysis of collagen and elastic fibers in normal skin and gingiva in relation to age
    • Gogly B, Godeau G, Gilbert S, et al. Morphometric analysis of collagen and elastic fibers in normal skin and gingiva in relation to age. Clin Oral Invest 1997;1:147-152.
    • (1997) Clin Oral Invest , vol.1 , pp. 147-152
    • Gogly, B.1    Godeau, G.2    Gilbert, S.3
  • 42
    • 0027234836 scopus 로고
    • Production and characterization of monoclonal antibodies raised against recombinant human granzymes A and B showing cross reactions with the neutral proteins
    • Kummer JA, Kamp AM, van Katwijk M, et al. Production and characterization of monoclonal antibodies raised against recombinant human granzymes A and B showing cross reactions with the neutral proteins. J Immunol Meth 1993;163:77-83.
    • (1993) J Immunol Meth , vol.163 , pp. 77-83
    • Kummer, J.A.1    Kamp, A.M.2    Van Katwijk, M.3
  • 43
    • 0023132276 scopus 로고
    • Cloned cytolytic T-effector cells and their malignant variants produce an extracellular matrix degrading trypsin-like serine proteinase
    • Simon MM, Simon HG, Fruth U, et al. Cloned cytolytic T-effector cells and their malignant variants produce an extracellular matrix degrading trypsin-like serine proteinase. Immunol 1987;60:219-230.
    • (1987) Immunol , vol.60 , pp. 219-230
    • Simon, M.M.1    Simon, H.G.2    Fruth, U.3
  • 44
    • 0027136685 scopus 로고
    • Human granzyme B degrades aggrecan proteoglycan in matrix synthesized by chondrocytes
    • Froelich CJ, Zhang X, Turbov J, et al. Human granzyme B degrades aggrecan proteoglycan in matrix synthesized by chondrocytes. J Immunol 1993;151:7161-7171.
    • (1993) J Immunol , vol.151 , pp. 7161-7171
    • Froelich, C.J.1    Zhang, X.2    Turbov, J.3
  • 45
    • 0031438087 scopus 로고    scopus 로고
    • Ultrastructural localization of cathepsin B in gingival tissue from chronic periodontitis patients
    • Kennett CN, Cox SW, Eley BM. Ultrastructural localization of cathepsin B in gingival tissue from chronic periodontitis patients. Histochem J 1997;29:727-734.
    • (1997) Histochem J , vol.29 , pp. 727-734
    • Kennett, C.N.1    Cox, S.W.2    Eley, B.M.3
  • 46
    • 8944249294 scopus 로고    scopus 로고
    • Phagocytosis and intracellular digestion of collagen, its role in turnover and remodelling
    • Everts V, van der Zee E, Creemers L, Beertsen W. Phagocytosis and intracellular digestion of collagen, its role in turnover and remodelling. Histochem J 1996;28:229-245.
    • (1996) Histochem J , vol.28 , pp. 229-245
    • Everts, V.1    Van Der Zee, E.2    Creemers, L.3    Beertsen, W.4
  • 47
    • 0026195021 scopus 로고
    • Importance of the host response in the periodontium
    • Seymour GJ. Importance of the host response in the periodontium. J Clin Periodontol 1991;18:421-426.
    • (1991) J Clin Periodontol , vol.18 , pp. 421-426
    • Seymour, G.J.1
  • 48
    • 0023076679 scopus 로고
    • Possible mechanisms involved in the immunoregulation of chronic inflammatory periodontal disease
    • Seymour GJ. Possible mechanisms involved in the immunoregulation of chronic inflammatory periodontal disease. J Dent Res 1987;66:2-9.
    • (1987) J Dent Res , vol.66 , pp. 2-9
    • Seymour, G.J.1
  • 49
    • 0024728959 scopus 로고
    • Aspects of distribution of plasma cells at the advancing front of the lesion in chronic periodontitis: A quantitative ultrastructural study
    • Joachim F, Sati K, Barber P, Newman HN, Osborn J. Aspects of distribution of plasma cells at the advancing front of the lesion in chronic periodontitis: A quantitative ultrastructural study. J Parodontol 1989;8:229-248.
    • (1989) J Parodontol , vol.8 , pp. 229-248
    • Joachim, F.1    Sati, K.2    Barber, P.3    Newman, H.N.4    Osborn, J.5
  • 50
    • 0026914264 scopus 로고
    • Detection of, and anti-collagen antibody produced by, CD5-positive B cells in inflamed gingival tissues
    • Sugawara M, Yamashita K, Yoshie H, Hara K. Detection of, and anti-collagen antibody produced by, CD5-positive B cells in inflamed gingival tissues. J Periodont Res 1992;27:489-498.
    • (1992) J Periodont Res , vol.27 , pp. 489-498
    • Sugawara, M.1    Yamashita, K.2    Yoshie, H.3    Hara, K.4


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