Left ventricular function in colon cancer patients receiving adjuvant fluoro-folate chemotherapy: An echocardiographic study

Oncology Reports

Volumn 7, Issue 4, 2000, Pages 887-890

  Balloni, Laura ^a   Porta, Camillo ^a,b   Rossi, Silvia ^b   Gola, Andrea ^b   Pugliese, Palma ^b   Ferrari, Silvia ^b   Bovio, Antonella ^b   Danova, Marco ^b   Riccardi, Alberto ^b  

^a UNIVERSITY OF PAVIA   (Italy)

^b FONDAZIONE IRCCS POLICLINICO SAN MATTEO   (Italy)

Author keywords

Adjuvant chemotherapy; Colon cancer patients; Echocardiography; Fluoro folates; Left ventricular function

Indexed keywords

ANTINEOPLASTIC AGENT; FLUOROURACIL;

ADJUVANT CHEMOTHERAPY; AGED; ARTICLE; CLINICAL TRIAL; COHORT ANALYSIS; COLON TUMOR; DIASTOLE; DRUG EFFECT; ECHOCARDIOGRAPHY; FEMALE; FOLLOW UP; HEART LEFT VENTRICLE FUNCTION; HUMAN; MALE; MIDDLE AGED; MULTICENTER STUDY; PATHOPHYSIOLOGY; SYSTOLE;

AGED; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CHEMOTHERAPY, ADJUVANT; COHORT STUDIES; COLONIC NEOPLASMS; DIASTOLE; ECHOCARDIOGRAPHY; FEMALE; FLUOROURACIL; FOLLOW-UP STUDIES; HUMANS; MALE; MIDDLE AGED; SYSTOLE; VENTRICULAR FUNCTION, LEFT;

EID: 0034219461     PISSN: 1021335X     EISSN: None     Source Type: Journal    
DOI: 10.3892/or.7.4.887     Document Type: Article

References (28)

1. Sobrero AF, Aschele C and Bertino JR: Fluorouracil in colorectal cancer - a tale of two drugs: implications for biochemical modulation. J Clin Oncol 15: 368-381, 1997.
2. Robben NC, Pippas AW and Moore JO: The syndrome of 5-fluorouracil cardiotoxicity. An elusive cardiopathy. Cancer 71: 493-509, 1993.
3. Gaveau T, Bauzet P, Marneffe H and Viars P: Cardiovascular disorders in the course of antimitotic infusions at high doses: 30 clinical cases. Anesth Analg Reanim 26: 311-327, 1969.
4. Anand AJ: Fluorouracil cardiotoxicity. Ann Pharmacother 28: 374-378, 1994.
5. Lemaire L, Malet-Martino MC, Martino R, De Forni M and Lasserre B: The Tris formulation of fluorouracil is more cardiotoxic than the sodium salt formulations. Oncol Rep 1: 173-174, 1994.
6. Lietaud T, Brain E, Golgran-Toledano D, et al: 5-Fluorouracil cardiotoxicity: a unique mechanism for ischaemic cardiopathy and cardiac failure? Eur J Cancer 32A: 368-369, 1996.
7. Thyss A, Gaspard MH, Marsault R, et al: Very high endothelin plasma levels in patients with 5-FU cardiotoxicity. Ann Oncol 3: 88, 1992.
8. Porta C, Moroni M, Ferrari S and Nastasi G: Endothelin-1 and 5-fluorouracil-induced cardiotoxicity. Neoplasma 45: 81-82, 1998.
9. International Multicentre Pooled Analysis of Colon Cancer Trials (IMPACT) Investigators: Efficacy of adjuvant fluorouracil and folinic acid in colon cancer. Lancet 345: 939-944, 1995.
10. Lee CH, Hogan JC and Gibson DG: Diastolic disease in left ventricular hypertrophy: comparison of M-mode and Doppler echocardiography for the assessment of rapid ventricular filling. Br Heart J 65: 194-200, 1991.
11. Montecucco C, Caporali R, Rossi S, Gola G and Finardi G: Left ventricular diastolic function in scleroderma. Br J Rheumatol 36: 609-610, 1997.
12. MacDonald JS: Adjuvant therapy for colon cancer. CA Cancer J Clin 47: 243-256, 1997.
13. Ganiats TG, Browner DK and Dittrich HC: Comparison of quality of well-being scale and NYHA functional status classification in patients with atrial fibrillation. New York Heart Association. Am Heart J 135: 819-824, 1998.
14. Gibson DG and Brown D: Measurement of instantaneous left ventricular dimension and filling rate in man using echocardiography. Br Heart J 35: 1141-1149, 1973.
15. Grandi AM, Marchesi E, Bignotti M, et al: Left ventricular diastolic function in hypertension: correlation with ambulatory blood pressure and left ventricular mass. Am J Noninvas Cardiol 7: 281-284, 1993.
16. Grandi AM, Venco A, Barzizza F, Casadei B, Marchesi E and Finardi G: Effect of Enalapril on left ventricular mass and performance in essential hypertension. Am J Cardiol 63: 1093-1097, 1989.
17. Devereux RB and Reichek N: Echocardiographic determination of left ventricular mass in man: anatomic validation of the method. Circulation 55: 613-618, 1977.
18. De Forni M, Malet-Martino MC, Jaillais P, et al: Cardiotoxicity of high-dose continous infusion fluorouracil: a prospective clinical study. J Clin Oncol 10: 1795-1801, 1992.
19. Akhtar SS, Salim KP and Bano ZA: Symptomatic cardiotoxicity with high-dose 5-fluorouracil infusion: a prospective study. Oncology 50: 441-444, 1993.
20. Harris BE, Carpenter JT and Diasio RB: Severe 5-fluorouracil toxicity secondary to dihydropyrimidine dehydrogenase deficiency. Cancer 68: 499-501, 1991.
21. Cwikiel M, Persson US, Larsson H, Albertsson M and Eskilsson J: Changes of blood viscosity in patients treated with 5-fluorouracil: a link to cardiotoxicity? Acta Oncol 34: 83-85, 1995.
22. Farooqi IS and Aronson JK: Iatrogenic chest pain: a case of 5-fluorouracil cardiotoxicity. Q J Med 89: 953-955, 1996.
23. Grandi AM, Pinotti G, Morandi E, et al: Noninvasive evaluation of cardiotoxicity of 5-fluorouracil and low dose of folinic acid: a one-year follow-up study. Ann Oncol 8: 705-708, 1997.
24. Pottage A, Holt S, Ludgate S and Langlands AO: Fluorouracil cardiotoxicity. Br Med J: 547, 1978.
25. Labianca R, Beretta G, Clerici M, et al: Cardiac toxicity of 5-FU: a study of 1083 patients. Tumori 68: 505-510, 1982.
26. Cassidy J and Farooqi IS: Iatrogenic chest pain and 5-fluorouracil cardiotoxicity. Q J Med 90: 305-306, 1997.
27. Zhang RW, Liu T, Soong SJ and Diasio RB: A mathematical model of the kinetics and tissue distribution of 2-fluoro-β-alanine, the major catabolite of 5-fluorouracil. Biochem Pharmacol 10: 2063-2069, 1993.
28. Millart H, Kantelip JP, Platonoff N, et al: Increased iron content in rat myocardium after 5-fluorouracil chronic administration. Anticancer Res 13: 779-784, 1993.