Effect of Flavonol Derivatives on the Carrageenin-Induced Paw Edema in the Rat and Inhibition of Cyclooxygenase-1 and 5-Lipoxygenase in Vitro

Archiv der Pharmazie

Volumn 333, Issue 7, 2000, Pages 205-210

  Sobottka, Andrea M ^a,b   Werner, Wolfgang ^b   Blaschke, Gottfried ^b   Kiefer, Werner ^c   Nowe, Ulrike ^c   Dannhardt, Gerd ^c   Schapoval, Elfrides E S ^a   Schenkel, Eloir P ^a   Scriba, Gerhard K E ^d  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b UNIVERSITY OF MÜNSTER   (Germany)

^c JOHANNES GUTENBERG UNIVERSITY   (Germany)

^d FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

5 lipoxygenase; Anti inflammatory activity; Cyclooxygenase 1; Flavonols; Rat paw edema

Indexed keywords

ANTIINFLAMMATORY AGENT; ARACHIDONATE 5 LIPOXYGENASE; CARRAGEENAN; CYCLOOXYGENASE 1; ENZYME INHIBITOR; FLAVONOID; FLAVONOL DERIVATIVE; ISOENZYME; MEMBRANE PROTEIN; PROSTAGLANDIN SYNTHASE; PROSTAGLANDIN SYNTHASE INHIBITOR; PTGS1 PROTEIN, RAT;

ANIMAL; ARTICLE; CATTLE; CHEMICALLY INDUCED DISORDER; COMPARATIVE STUDY; DRUG ANTAGONISM; EDEMA; FOOT; IC 50; PATHOLOGY; RAT; SYNTHESIS; WISTAR RAT;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ARACHIDONATE 5-LIPOXYGENASE; CARRAGEENAN; CATTLE; CYCLOOXYGENASE 1; CYCLOOXYGENASE INHIBITORS; EDEMA; ENZYME INHIBITORS; FLAVONOIDS; FLAVONOLS; FOOT; INHIBITORY CONCENTRATION 50; ISOENZYMES; MEMBRANE PROTEINS; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RATS; RATS, WISTAR;

EID: 0034218848     PISSN: 03656233     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4184(20007)333:7<205::AID-ARDP205>3.0.CO;2-Y     Document Type: Article

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