Repression of aberrant splicing in human β-globin pre-mRNA with HbE mutation by antisense oligoribonucleotide or splicing factor SF2/ASF

International Journal of Hematology

Volumn 72, Issue 1, 2000, Pages 28-33

  Fukumaki, Yasuyuki ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

Aberrant splicing; Antisense oligoribonucleotide; Hemoglobin E; Mutation; SF2 ASF

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; GLOBIN; HEMOGLOBIN E; NUCLEAR PROTEIN; SFRS1 PROTEIN, HUMAN;

ARTICLE; DRUG EFFECT; GENETIC TRANSFECTION; GENETICS; HELA CELL; HEMOGLOBINURIA; HUMAN; RNA SPLICING;

GLOBINS; HELA CELLS; HEMOGLOBIN E; HEMOGLOBINURIA; HUMANS; NUCLEAR PROTEINS; OLIGORIBONUCLEOTIDES, ANTISENSE; RNA SPLICING; TRANSFECTION;

EID: 0034218721     PISSN: 09255710     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (4)

1. E-globin gene. Nature. 1982;300:768-769.
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3. E-globin mRNA on clinical severity of β-thalassemia/hemoglobin E disease. Southeast Asian J Trop Med Public Health. 1995;1:241-245.
4. Wagner RW. Gene inhibition using antisense oligodeoxynucleotides. Nature. 1994;372:333-335.