Tissue- and stage-specific modulation of Wingless signaling by the segment polarity gene lines

Genes and Development

Volumn 14, Issue 11, 2000, Pages 1364-1376

  Hatini, Victor ^a,b   Bokor, Peter ^a   Goto Mandeville, Ryoko ^a   DiNardo, Stephen ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b ROCKEFELLER UNIVERSITY   (United States)

Author keywords

Dorsal embryonic epidermis; Hedgehog; Lines; Patterning; Segment polarity genes; Wingless

Indexed keywords

ARTICLE; CELL FATE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DROSOPHILA; EMBRYO; EMBRYO PATTERN FORMATION; EMBRYO POLARITY; EPIDERMIS; GENE ACTIVATION; GENE CONTROL; GENE FUNCTION; GENETIC ANALYSIS; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ANIMALS; BODY PATTERNING; CARRIER PROTEINS; CELL LINEAGE; CELL NUCLEUS; CLONING, MOLECULAR; DROSOPHILA; DROSOPHILA PROTEINS; EMBRYO, NONMAMMALIAN; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENOTYPE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; INSECT PROTEINS; MUTAGENESIS; PROTO-ONCOGENE PROTEINS; RNA, MESSENGER; SIGNAL TRANSDUCTION; TIME FACTORS; TISSUE DISTRIBUTION;

EID: 0034212777     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (65)

1. Akiyoshi, S., H. Inoue, J. Hanai, K. Kusanagi, N. Nemoto, K. Miyazono, and M. Kawabata. 1999. c-Ski acts as a transcriptional co-repressor in transforming growth factor-beta signaling through interaction with smads. J. Biol. Chem. 274: 35269-35277.
2. Alexandre, C., M. Lecoutois, and J.-P. Vincent. 1999. Wingless and Hedgehog pattern Drosophila denticle belts by regulating the production of short-range signals. Development 126: 5689-5698.
3. Baker, N.E. 1987. Molecular cloning of sequences from wingless a segment polarity gene in Drosophila: The spatial distribution of a transcript in embryos. EMBO J. 6: 1765-1773.
4. _. 1988. Embryonic and imaginai requirements for wg, a segment polarity gene in Drosophila. Dev. Biol. 125: 96-108.
5. Behrens, J., J.P. von Kries, M. Kühl, L. Bruhn, D. Wedlich, R. Grosschedl, and W. Birchmeier. 1996. Functional interaction of β-catenin with the transcription factor LEF-1. Nature 382: 638-642.
6. Bejsovec, A. and A. Martinez-Arias. 1991. Roles of wingless in patterning the larval epidermis of Drosophila. Development 113: 471-485.
7. Benedyk, M.J., J.R. Mullen, and S. DiNardo. 1994. odd-paired: A zinc finger pair-rule protein required for the timely activation of engrailed and wingless in Drosophila embryos. Genes & Dev. 8: 105-117.
8. Bhanot, P., M. Fish, J. A. Jemison, R. Nusse, J. Nathans, and K.M. Cadigan. 1999. Frizzled and Dfrizzled-2 function as redundant receptors for Wingless during Drosophila embryonic development. Development 126: 4175-4186.
9. Bhat, K.M. 1998. frizzled and frizzled 2 play a partially redundant role in wingless signaling and have similar requirements to wingless in neurogenesis. Cell 95: 1027-1036.
10. Bier, E., L.Y. Jan, and Y.N. Jan. 1990. Rhomboid a gene required for dorsoventral axis establishment and peripheral nervous system development in Drosophila melanogaster. Genes & Dev. 4: 190-203.
11. Bokor, P. and S. DiNardo. 1996. The roles of hedgehog, wingless and lines in patterning the dorsal epidermis in Drosophila. Development 122: 1083-1092.
12. Brannon, M., M. Gomperts, L. Sumoy, R.T. Moon, and D. Kimelman. 1997. A β-catenin/XTcf-3 complex binds to the siamois promoter to regulate dorsal axis specification in Xenopus. Genes & Dev. 11: 2359-2370.
13. Brook, W.J. and S.M. Cohen. 1996. Antagonistic interactions between wingless and decapentaplegic responsible for dorsal-ventral pattern in the Drosophila Leg. Science 273: 1373-1377.
14. Brown, N.H. and F.C. Kafatos. 1988. Functional cDNA libraries from Drosophila embryos, J. Mol. Biol. 203: 425-437.
15. Brunner, E., O. Peter, L. Schweizer, and K. Basler. 1997. pangolin encodes a Lef-1 homologue that acts downstream of armadillo to transduce the Wingless signal in Drosophila. Nature 385: 829-833.
16. Cabrera, C.V., M.C. Alonso, P. Johnston, R.G. Phillips, and P.A. Lawrence. 1987. Phenocopies induced with antisense RNA identify the wingless gene. Cell 50: 659-663.
17. Castelli-Gair, J. 1998. The lines gene of Drosophila is required for specific functions of the Abdominal-B HOX protein. Development 125: 1269-1274.
18. Cavallo, R.A., R.T. Cox, M.M. Moline, J. Roose, G.A. Polevoy, H. Clevers, M. Peifer, and A. Bejsovec. 1998. Drosophila Tcf and Groucho interact to repress Wingless signalling activity. Nature 395: 604-608.
19. Chen, C. and G. Struhl. 1999. Wingless transduction by the frizzled and frizzled2 proteins of drosophila. Development 126: 5441-5452.
20. Chou, T.B., E. Noll, and N. Perrimon. 1993. Autosomal P[o-voD1] dominant female-sterile insertions in Drosophila and their use in generating germ-line chimeras. Development 119: 1359-1369.
21. de Zulueta, P., E. Alexandre, B. Jacq, and S. Kerridge. 1994. Homeotic complex and teashirt genes co-operate to establish trunk segmental identities in Drosophila. Development 120: 2287-2296.
22. Dierick, H. and A. Bejsovec. 1999. Cellular mechanisms of wingless/Wnt signal transduction. Curr. Top. Dev. Biol. 43: 153-190.
23. DiNardo, S., E. Sher, J. Heemskerk-Jongens, J.A. Kassis, and P.H. O'Farrell. 1988. Two-tiered regulation of spatially patterned engrailed gene expression during drosophila embryogenesis. Nature 332: 604-609.
24. Dougan, S.T. and S. DiNardo. 1992. wingless generates cell type diversity among engrailed expressing cells. Nature 360: 347-350.
25. Fagotto, F., U. Gluck, and B.M. Gumbiner. 1998. Nuclear localization signal-independent and importin/karyopherin-independent nuclear import of beta-catenin. Curr. Biol. 8: 181-190.
26. Feng, X.H., Y. Zhang, R.Y. Wu, and R. Derynck. 1998. The tumor suppressor Smad4/DPC4 and transcriptional adaptor CBP/p300 are coactivators for smad3 in TGF-β-induced transcriptional activation. Genes & Dev. 12: 2153-2163.
27. Gallet, A., C. Angelats, A. Erkner, B. Charroux, L. Fasano, and S. Kerridge. 1999. The C-terminal domain of armadillo binds to hypophosphorylated teashirt to modulate wingless signalling in Drosophila. EMBO J. 18: 2208-2217.
28. Gallet, A., A. Erkner, B. Charroux, L. Fasano, and S. Kerridge. 1998. Trunk-specific modulation of wingless signalling in Drosophila by teashirt binding to armadillo. Curr. Biol. 8: 893-902.
29. Giese, K., J. Cox, and R. Grosschedl. 1992. The HMG domain of lymphoid enhancer factor 1 bends DNA and facilitates assembly of functional nucleoprotein structures. Cell 69: 185-195.
30. Gritzan, U., V. Hatini, and S. DiNardo. 1999. Mutual antagonism between signals secreted by adjacent wingless and engrailed cells leads to specification of complementary regions of the Drosophila parasegment. Development 126: 4107-4115.
31. Heemskerk, J. and S. DiNardo. 1994. Drosophila hedgehog acts as a morphogen in cellular patterning. Cell 76: 449-460.
32. Ishitani, T., J. Ninomiya-Tsuji, S. Nagai, M. Nishita, M. Meneghini, N. Barker, M. Waterman, B. Bowerman, H. Clevers, H. Shibuya, and K. Matsumoto. 1999. The TAK1-NLK-MAPK-related pathway antagonizes signalling between β-catenin and transcription factor TCF. Nature 399: 798-802.
33. Jiang, J. and G. Struhl. 1996. Complementary and mutually exclusive activities of decapentaplegic and wingless organize axial patterning during Drosophila leg development. Cell 86: 401-409.
34. Kennerdell, J.R. and R.W. Carthew. 1998. Use of dsRNA-mediated genetic interference to demonstrate that frizzled and frizzled 2 act in the wingless pathway. Cell 95: 1017-1026.
35. Lawrence, P.A., B. Sanson, and J.P. Vincent. 1996. Compartments, wingless and engrailed: Patterning the ventral epidermis of Drosophila embryos. Development 122: 4095-4103.
36. Luo, K., S.L. Stroschein, W. Wang, D. Chen, E. Martens, S. Zhou, and Q. Zhou. 1999. The Ski oncoprotein interacts with the Smad proteins to repress TGFbeta signaling. Genes & Dev. 13: 2196-2206.
37. Martinez-Arias, A., N.E. Baker, and P.W. Ingham. 1988. Role of segment polarity genes in the definition and maintenance of cell states in the Drosophila embryo. Development 103: 157-170.
38. Meneghini, M.D., T. Ishitani, J.C. Carter, N. Hisamoto, J. Ninomiya-Tsuji, C.J. Thorpe, D.R. Hamill, K. Matsumoto, and B. Bowerman. 1999. MAP kinase and Wnt pathways converge to downrcgulate an HMG-domain repressor in Caenorhabditis elegans. Nature 399: 793-797.
39. Molenaar, M., M. van de Wetering, M. Oosterwegel, J. Peterson-Maduro, S. Godsave, V. Korinek, J. Roose, O. Destree, and H. Clevers. 1996. XTcf-3 transcription factor mediates β-catenin-induced axis formation in Xenopus embryos. Cell 86: 391-399.
40. Muller, H., R. Samanta, and E. Wieschaus. 1999. Wingless signaling in the Drosophila embryo: Zygotic requirements and the role of the frizzled genes. Development 126: 577-586.
41. Noordermeer, J., P. Johnston, F. Rijsewik, R. Nusse, and P.A. Lawrence. 1992. The consequences of ubiquitous expression of the wingless gene in the Drosophila embryo. Development 116: 711-719.
42. Nüsslein-Volhard, C. and E. Wieschaus. 1980. Mutations affecting segment number and polarity in Drosophila. Nature 287: 795-801.
43. Nüsslein-Volhard, C., E. Wieschaus, and H. Kluding. 1984. Mutations affecting the pattern of the larval cuticle in Drosophila melanogaster. I. Zygotic loci on the second chromosome. Roux's Arch. Dev. Biol. 193: 267-282.
44. O' Keefe, L., S.T. Dougan, L. Gabay, E. Raz, B.Z. Shilo, and S. DiNardo. 1997. Spitz and Wingless, emanating from distinct borders, cooperate to establish cell fate across the Engrailed domain in the Drosophila epidermis. Development 124: 4837-4845.
45. Pai, L.M., S. Orsulic, A. Bejsovec, and M. Peifer. 1997. Negative regulation of Armadillo, a Wingless effector in Drosophila. Development 124: 2255-2266.
46. Patel, N.H., E. Martin-Blanco, K.G. Coleman, S.J. Poole, M.C. Ellis, T.B. Kornberg, and C.S. Goodman. 1989. Expression of engrailed proteins in arthropods, annelids, and chordates. Cell 58: 955-968.
47. Payre, F., A. Vincent, and S. Carreno. 1999. ovo/svb integrates Wingless and DER pathways to control epidermis differentiation. Nature 400: 271-275.
48. Pringle, J., A. Adams, D. Drubin, and B. Haaker. 1991. Immunofluorescence methods for yeast. In Guide to yeast genetics and molecular biology (ed. C. Guthrie and G. Fink), pp. 581-584.
49. Riese, J., X. Yu, A. Munnerlyn, S. Eresh, S.C. Hsu, R. Gross-chedl, and M. Bienz. 1997. LEF-1, a nuclear factor coordinating signaling inputs from wingless and decapentaplegic. Cell 88: 777-787.
50. Rijsewijk, F., M. Scheurmann, E. Wagenaar, P. Parren, D. Weigel, and R. Nusse. 1987. The Drosophila homolog of the mouse mammary oncogene int-1 is identical to the segment polarity gene wingless. Cell 50: 649-657.
51. Rocheleau, C.E., J. Yasuda, T.H. Shin, R. Lin, H. Sawa, H. Okano, J.R. Priess, R.J. Davis, and C.C. Mello. 1999. WRM-1 activates the LIT-1 protein kinase to transduce anterior/posterior polarity signals in C. elegans. Cell 97: 717-726.
52. Roose, J., M. Molenaar, J. Peterson, J. Hurenkamp, H. Brantjes, P. Moerer, M. van de Wetering, O. Destree, and H. Clevers. 1998. The Xenopus Wnt effector XTcf-3 interacts with Groucho-related transcriptional repressors. Nature 395: 608-612.
53. Rulifson, E.J., C.A. Micchelli, J.D. Axelrod, N. Perrimon, and S.S. Blair. 1996. wingless refines its own expression domain on the Drosophila wing margin. Nature 384: 72-74.
54. Sanson, B., C. Alexandre, N. Fascetti, and J.-P. Vincent. 1999. Engrailed and Hedgehog make the range of Wingless asymmetric in Drosophila embryos. Cell 98: 207-216.
55. Speicher, S.A., U. Thomas, U. Hinz, and E. Knust. 1994. The Serrate locus of Drosophila and its role in morphogenesis of the wing imaginai discs: Control of cell proliferation. Development 120: 535-544.
56. Spemann. 1938. Embryonic development and induction. Yale University Press, New Haven, CT.
57. Szüts, D., M. Freeman, and M. Bienz. 1997. Antagonism between EGFR and Wingless signaling in the larval cuticle of Drosophila, Development 124: .
58. Tabata, T., S. Eaton, and T.B. Kornberg. 1992. The Drosophila hedgehog gene is expressed specifically in posterior compartment cells and is a target of engrailed regulation. Genes & Dev. 6: 2635-2645.
59. van de Wetering, M., R. Cavallo, D. Dooijes, M. van Beest, J. van Es, J. Loureiro, A. Ypma, D. Hursh, T. Jones, A. Bejsovec, M. Peifer, M. Mortin, and H. Clevers. 1997. Armadillo coactivates transcription driven by the product of the Drosophila segment polarity gene dTCF. Cell 88: 789-799.
60. van den Heuvel, M., J. Klingensmith, N. Perrimon, and R. Nusse. 1993. Cell patterning in the Drosophila segment: Engrailed and wingless antigen distributions in segment polarity mutant embryos. Development (Suppl.) :105-114.
61. van der Meer, S. 1977. Optical clean and permanent whole mount preparation for phase contrast microscopy of cuticular structures of insect larvae. Drosophila Inf. Serv. 52: 160-161.
62. Waltzer, L. and M. Bienz. 1998. Drosophila CBP represses the transcription factor TCF to antagonize Wingless signalling. Nature 395: 521-525.
63. Wiellette, E.L. and W. McGinnis. 1999. Hox genes differentially regulate Serrate to generate segment-specific structures. Development 126: 1985-1995.
64. Wieschaus, E. and C. Nüsslein-Volhard. 1986. Looking at embryos in Drosophila: A practical approach, pp. 199-227. IRL Press, Oxford, UK.
65. Wotton, D., R.S. Lo, S. Lee, and J. Massagué. 1999. A Smad transcriptional corepressor. Cell 97: 29-39.