Human sperm immobilization effect of Carica papaya seed extracts: An in vitro study

Asian Journal of Andrology

Volumn 2, Issue 2, 2000, Pages 103-109

  Lohiya, Nirmal K ^a   Kothari, Lalit K ^b   Manivannan, B ^a   Mishra, Pradyumna K ^a   Pathak, Neelam ^a  

^a UNIVERSITY OF RAJASTHAN   (India)

^b Reproductive Medicine Clinic   (India)

Author keywords

Carica papaya; Human sperm; Sperm immobilization; Spermicidal agents

Indexed keywords

PLANT EXTRACT; SPERMICIDAL AGENT;

ARTICLE; DRUG EFFECT; ELECTRON MICROSCOPY; FRUIT; HUMAN; MALE; PLANT SEED; SPERMATOZOON MOTILITY;

FRUIT; HUMANS; MALE; MICROSCOPY, ELECTRON; PLANT EXTRACTS; SEEDS; SPERM IMMOBILIZING AGENTS; SPERM MOTILITY;

EID: 0034208855     PISSN: 1008682X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (17)

1. Farnsworth NR, Waller DP. Current Status of plant products reported to inhibit sperm. In: Zatuchni GI, editor. Research frontiers in fertility regulation 1982; 2: 1-16.
2. Setty BS, Kamboj VP, Khanna NM. Screening of Indian plants for biological activity: Part VII-spermicidal activity of Indian plants. Ind J Exp Biol 1977; 15: 231-2.
3. Lohiya NK, Goyal RB. Antifertility investigations on the crude chloroform extract of Carica papaya Linn. seeds in male albino rats. Ind J Exp Biol 1992; 30: 1051-5.
4. Pathak N, Mishra PK, Manivannan B, Lohiya NK. Sterility due to inhibition of sperm motility by oral administration of benzene Chromatographic fraction of the chloroform extract of the seeds of Carica papaya in rats. Phytomedicine (In press).
5. Lohiya NK, Pathak N, Mishra PK, Manivannan B. Reversible contraception with choloroform extract of Carica papaya Linn. seeds in male rabbits. Reprod Toxicol 1999; 13: 59-66.
6. Lohiya NK, Mishra PK, Pathak N, Manivannan B, Jain SC. Reversible azoospermia by oral administration of the benzene Chromatographic fraction of the chloroform extract of the seeds of Carica papaya in rabbits. Advances in Contraception 1999; 15: 141-61.
7. Goyal RB. Post-testicular antifertility effects of Carica papaya seed extracts. Ph.D. Thesis, University of Rajasthan, Jaipur, India, 1991.
8. WHO Laboratory manual for the examination of human semen and sperm-cervical mucus interaction. 4th ed. Cambridge: Cambridge University Press; 1999.
9. Schul WB, Wolff HH. Ultrastructure of human spermatozoa in the presence of the spermicide nonoxynol-9 and a vaginal contraceptive containing nonoxynol-9. Andrologia 1981; 13: 42-9.
10. Wilborn WH, Hahn DW, McGuire JJ. Scanning electron microscopy of human spermatozoa after incubation with the spermicide nonoxynol-9. Fertil Steril 1983; 39: 717-9.
11. Primorac M, Sekulovic D, Antonic S. In vitro determination of the spermicidal activity of plant saponins. Pharmazie 1985; 40: 585.
12. Kamboj VP, Dhawan BN. Research on plants for fertility regulation in India. J Ethnopharmacol 1982; 6: 191-226.
13. Jain GK, Pal R, Khanna NM. Spermicidal saponins from Pittosporum nilghirense Wight et Apnott. Ind J Pharm Sci 1980; 42: 12-3.
14. Kamboj VP, Dhawan BN. Fertility regulating plants on Indian scene - an update. Contraceptive Research Today and Tomorrow. New Delhi: Indian Council of Medical Research 1989. p 115-25.
15. Talwar GP, Garg S, Dhar V, Chabra R, Ganju A, Upadhyay SN. Praneem polyherbal cream and pessaries with dual properties of contraception and alleviation of genital infections. Curr Sci 1995; 68: 437-40.
16. Ross IA. Carica papaya L. In: Ross IA, editor. Medicinal Plants of the World. Totowa, NJ: Humana Press Inc; 1999.
17. Emeruwa AC. Antibacterial substance from Carica papaya fruit extract. J Nat Products 1982; 45: 123-7.