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Diet-induced obese mice develop peripheral, but not central, resistance to leptin
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Vanheek M, Compton DS, France CF, et al.: Diet-induced obese mice develop peripheral, but not central, resistance to leptin. J Clin Invest 1997, 99: 385-390. This important paper demonstrated that diet-induced obesity is associated with leptin resistance, which can be localized to a failure of transport of leptin across the blood-brain barrier.
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(1997)
J Clin Invest
, vol.99
, pp. 385-390
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Vanheek, M.1
Compton, D.S.2
France, C.F.3
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