The effect of alcohol abuse on the risk of NSAID-related gastrointestinal events

Annals of Epidemiology

Volumn 10, Issue 4, 2000, Pages 246-250

  Neutel, C Ineke ^a   Appel, W Curt ^b  

^a HEALTH CANADA   (Canada)

^b Kusuri Canada Corp   (Canada)

Author keywords

Adverse Drug Reaction; Alcohol Abuse; Gastrointestinal Complications; NSAIDs; Pharmacoepidemiology

Indexed keywords

NON PRESCRIPTION DRUG; NONSTEROID ANTIINFLAMMATORY AGENT;

ADULT; AGED; ALCOHOL ABUSE; ARTICLE; CONTROLLED STUDY; FEMALE; FOOD AND DRUG ADMINISTRATION; GASTROINTESTINAL DISEASE; HUMAN; MAJOR CLINICAL STUDY; MALE; PATIENT INFORMATION; PRIORITY JOURNAL; RISK ASSESSMENT;

ADULT; AGE DISTRIBUTION; AGED; AGED, 80 AND OVER; ALCOHOLISM; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CASE-CONTROL STUDIES; COMORBIDITY; CONFIDENCE INTERVALS; FEMALE; GASTROINTESTINAL DISEASES; HEALTH SURVEYS; HUMANS; INCIDENCE; MALE; MIDDLE AGED; ODDS RATIO; REFERENCE VALUES; RISK FACTORS; SEX DISTRIBUTION;

EID: 0034194524     PISSN: 10472797     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1047-2797(00)00040-5     Document Type: Article

References (24)

1. Food and Drug Administration, Department of Health and Human Services. Over-the-counter drug products containing analgesic/antipyretic active ingredients for internal use; required alcohol warning. Fed Register. 1998;63(205):56789-56802.
2. Carson J.L., Strom B.L., Morse M.L., West S.L., Soper K.A., Stolley P.D.et al. The relative gastrointestinal toxicity of the non-steroidal anti-inflammatory drugs. Arch Int Med. 147:1987;1054-1059.
3. Beard K., Walker A.M., Perera D.R., Jick H. Nonsteroidal anti-inflammatory drugs and hospitalization for gastroesophageal bleeding in the elderly. Arch Int Med. 147:1987;1621-1623.
4. Guess H.A., West R., Strand L.M., Helston D., Lydick E.G., Bergman U.et al. Fatal upper gastrointestinal hemorrhage or perforation among users and nonusers of nonsteroidal anti-inflammatory drugs in Saskatchewan, Canada, 1983. J Clin Epidemiol. 41:1988;35-45.
5. Gutthann S.P., Garcia Rodriguez L.A., Raiford D.S. Individual nonsteroidal anti-inflammatory drugs and other risk factors for upper gastrointestinal bleeding and perforation. Epidemiology. 8:1997;18-24.
6. Garcia Rodriguez L.A., Jick H. Risk of upper gastrointestinal bleeding and perforation associated with individual non-steroidal anti-inflammatory drugs. Lancet. 343:1994;769-772.
7. Griffin M.R., Piper J.M., Daugherty J.R., Snowden M., Ray W.A. Nonsteroidal anti-inflammatory drug use and increased risk for peptic ulcer disease in elderly persons. Ann Int Med. 114:1991;257-262.
8. Singh G., Ramey D.R., Morfeld D., Fries J.F. Comparative toxicity of non-steroidal anti-inflammatory agents. Pharmacol Ther. 62:1994;175-191.
9. Langman M.J., Weil J., Wainright P., Lawson D.H., Rawlins M.D., Logan R.F.et al. Risk of bleeding peptic ulcer associated with non-steroidal anti-inflammatory drugs. Lancet. 343:1994;1075-1078.
10. Tarnawski A., Hollander D., Stachura J., Klimczyk B., Mach T., Bogdal J. Alcohol injury to the normal gastric mucosa. Endoscopic, histologic and functional assessment Clin Invest Med. 10:1987;259-263.
11. Carson J.L., Strom B.L., Soper K.A., West S.L., Morse M.L. The association of non-steroidal anti-inflammatory drugs with upper gastrointestinal bleeding. Arch Int Med. 147:1987;85-88.
12. Chan T.Y., Critchley J.A., Lau J.T., Sung J.J., Chung S.S., Anderson D.C. The relationship between upper gastrointestinal hemorrhage and drug use. A case-control study Intl J Clin Pharmacol Ther. 34:1996;304-308.
13. Hansen J.M., Hallas J., Lauritsen J.M., Bytzer P. NSAID and ulcer complications. An analysis of risk factors. Ugeskr Laeger. 159:1997;3787-3791.
14. Hochain P., Berkelmans I., Czernichow P., Duhamel C., Tranvouez J.L., Lerebours E.et al. Which patients taking non-aspirin non-steroidal anti-inflammatory drugs bleed? A case-control study. Eur J Gastroenterol Hepatol. 7:1995;419-426.
15. Holvoet J., Terriere L., Van Hee W., Verbist L., Fierens E., Hautekeete M.L. Relation of upper gastrointestinal bleeding to non-steroidal anti-inflammatory drugs and aspirin. A case-control study Gut. 32:1991;730-734.
16. Kelly J.P., Kaufman D.W., Jurgelon J.M., Sheehan J., Koff R.S., Shapiro S. Risk of aspirin-associated major upper-gastrointestinal bleeding with enteric-coated or buffered product. Lancet. 348:1996;1413-1416.
17. Nobili A., Mosconi P., Franzosi M.G., Tognoni G. Non-steroidal anti-inflammatory drugs and upper gastrointestinal bleeding. A postmarketing surveillance case-control study Pharmacoepidemiol Drug Safety. 1:1992;65-72.
18. Bloom B.S. Risk and cost of gastrointestinal side effects associated with nonsteroidal anti-inflammatory drugs. Arch Int Med. 149:1989;1019-1022.
19. Henry D., Dobson A., Turner C. Variability in the risk of major gastrointestinal complications from nonaspirin nonsteroidal anti-inflammatory drugs. Gastroenterology. 105:1993;1078-1088.
20. Kaufman DW, Kelly JP, Sheehan JE, Wiholm B-E, Laszlo A, Alfredsson L, et al. The risk of major upper gastrointestinal bleeding among users of nonsteroidal anti-inflammatory drugs at various levels of alcohol consumption. Presentation to International Conference of Pharmacoepidemiology. Orlando, FL; August 1997.
21. Rothman KJ, Greenland S. Modern Epidemiology. Philadelphia, PA: Lippincott-Raven; 1998:254.
22. Malcolm E., Downey W., Strand L.M., McNutt M., West R. Saskatchewan health linkable databases and pharmacoepidemiology. Postmarket Surveill. 6:1993;175-264.
23. WHO International Classification of Diseases. 9th ed:1977;WHO, Geneva.
24. SAS Institute Inc. SAS User Guide. 6.03 ed. Cary, NC: SAS Institute Inc.; 1988.