Molecular prenatal diagnosis of thalassemia in Taiwan

International Journal of Gynecology and Obstetrics

Volumn 69, Issue 2, 2000, Pages 103-106

  Chern, Schu Rern ^a   Chen, Chih Ping ^a  

^a MACKAY MEMORIAL HOSPITAL   (Taiwan)

Author keywords

High throughput sequencing; Polymerase chain reaction (PCR); Prenatal diagnosis; Thalassemia

Indexed keywords

DNA FRAGMENT;

ARTICLE; BETA THALASSEMIA; CLINICAL ARTICLE; DISEASE CARRIER; DNA SEQUENCE; FETUS; FETUS HYDROPS; FOLLOW UP; GENETIC DISORDER; HUMAN; MOLECULAR GENETICS; MUTATION; POLYMERASE CHAIN REACTION; PRENATAL DIAGNOSIS; PREVALENCE; PRIORITY JOURNAL; SCREENING; TAIWAN; TECHNIQUE; THALASSEMIA; THALASSEMIA MAJOR; THALASSEMIA MINOR;

EID: 0034194144     PISSN: 00207292     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0020-7292(99)00211-8     Document Type: Article

References (11)

1. T.M Ko F.J Hsieh P.M Hsu T.Y Lee Molecular characterization of severe α-thalassemia causing hydrops fetalis in Taiwan Am J Med Genet 39 1991 317 320
2. S.H Orkin H.H.J Kazazian The mutation and polymorphism of the human β-globin gene and its surrounding DNA Annu Rev Genet 18 1984 131 171
3. J.G Chang C.P Lin T.C Liu S.S Chiou P.H Chen L.S Lee Molecular basis of β-thalassemia minor in Taiwan Int J Hematol 59 1994 267 272
4. J.G Chang H.J Liu Molecular diagnosis of thalassemia in Taiwan Kaohsiung J Med Sci 11 1995 371 378
5. R.D Nicholls N Rischel-Ghodsian D.R Higgs Recombination of human α-globin gene cluster: sequence features and topological constrains Cell 49 1987 369 378
6. R.M Lawn A Efstratiadis C O’Connell T Maniatis The nucleotide sequence of the human β-globin gene Cell 21 1980 647 651
7. G.L Semenza C.E Dowling H.H.J Kazazian Hin f I polymorphism 3′ to the human β-globin gene detected by the polymerase chain reaction (PCR) Nucl Acid Res 17 1989 2376
8. J.G Chang J.M Lu J.M Huang J.T Chen H.J Liu C.P Chang Rapid diagnosis of β-thalassemia by mutagenically separated polymerase chain reaction (MS-PCR) and its application to prenatal diagnosis Br J Hematol 91 1995 602 607
9. T.C Liu S.F Lin T.Y Yang J.P Lee T.P Chen J.G Chang Prenatal diagnosis of thalassemia in the Chinese Am J Hematol 55 1997 65 68
10. J.G Chang C.P Chen H.J Ho C.P Lin L.S Lee P.H Chen Rapid prenatal diagnosis of Hb Bart’s hydrops fetalis in Southern Asia area by polymerase chain reaction Int J Hematol 56 1992 155 159
11. T.M Ko L.H Tseng F.J Hsieh P.M Hsu T.Y Lee Carrier detection and prenatal diagnosis of alpha-thalassemia of Southeast Asian deletion by polymerase chain reaction Hum Genet 88 1992 245 248