Paroxetine binding to the rat norepinephrine transporter in vivo

Biological Psychiatry

Volumn 47, Issue 9, 2000, Pages 842-845

  Owens, Michael J ^a   Knight, David L ^a   Nemeroff, Charles B ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Drug concentrations; Norepinephrine transporter; Norepinephrine uptake; Paroxetine; Selectivity; 3H nisoxetine binding

Indexed keywords

ALPHA ADRENERGIC RECEPTOR; ANTIDEPRESSANT AGENT; PAROXETINE;

AFFECTIVE NEUROSIS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANXIETY NEUROSIS; ARTICLE; CONTROLLED STUDY; DEPRESSION; DRUG EFFECT; DRUG POTENCY; DRUG PROTEIN BINDING; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; BIOLOGICAL TRANSPORT, ACTIVE; CALIBRATION; CARRIER PROTEINS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FLUOXETINE; MALE; NOREPINEPHRINE; NOREPINEPHRINE PLASMA MEMBRANE TRANSPORT PROTEINS; PAROXETINE; RATS; RATS, SPRAGUE-DAWLEY; SEROTONIN UPTAKE INHIBITORS; SPECTROPHOTOMETRY, ULTRAVIOLET; SYMPORTERS;

EID: 0034193224     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3223(99)00314-5     Document Type: Article

References (6)

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6. 3H]-Nisoxetine A radioligand for quantitation of norepinephrine uptake sites by autoradiography or by homogenate binding. J Pharmacol Exp Ther. 260:1992;427-436.