Combined modality treatment of locally advanced breast carcinoma in elderly patients or patients with severe comorbid conditions using tamoxifen as the primary therapy

Cancer

Volumn 88, Issue 9, 2000, Pages 2054-2060

  Hoff, Paulo M ^a   Valero, Vicente ^a   Buzdar, Aman U ^a   Singletary, S Eva ^a   Theriault, Richard L ^a   Booser, Daniel ^a   Asmar, Lina ^a   Frye, Debra ^a   McNeese, Marsha D ^a   Hortobagyi, Gabriel N ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Locally advanced breast carcinoma; Multimodality treatment; Neoadjuvant; Tamoxifen

Indexed keywords

LETROZOLE; TAMOXIFEN;

ADJUVANT THERAPY; ADULT; ADVANCED CANCER; AGED; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CARCINOMA; CANCER RADIOTHERAPY; CANCER STAGING; CANCER SURGERY; CANCER SURVIVAL; CLINICAL ARTICLE; COMORBIDITY; DISEASE SEVERITY; DRUG EFFICACY; FEMALE; HORMONAL THERAPY; HUMAN; MALE; MULTIMODALITY CANCER THERAPY; PRIORITY JOURNAL;

AGE FACTORS; AGED; AGED, 80 AND OVER; ANTINEOPLASTIC AGENTS, HORMONAL; BREAST NEOPLASMS; CARCINOMA; DISEASE; DISEASE-FREE SURVIVAL; ENDOMETRIAL NEOPLASMS; ESTROGEN ANTAGONISTS; FEASIBILITY STUDIES; FEMALE; FOLLOW-UP STUDIES; FRAIL ELDERLY; HUMANS; MASTECTOMY, SEGMENTAL; MIDDLE AGED; NEOADJUVANT THERAPY; NEOPLASM RECURRENCE, LOCAL; NEOPLASM STAGING; RECEPTORS, ESTROGEN; REMISSION INDUCTION; SELECTIVE ESTROGEN RECEPTOR MODULATORS; SURVIVAL RATE; TAMOXIFEN; TREATMENT OUTCOME;

EID: 0034192182     PISSN: 0008543X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0142(20000501)88:9<2054::AID-CNCR11>3.0.CO;2-J     Document Type: Article

References (31)

1. Seidman H, Gelb S, Silverberg E, LaVerda N, Lubera JA. Survival experience in the Breast Cancer Detection Demonstration Project. Ca Cancer J Clin 1987;37:258.
2. Haagensen C, Stout A. Carcinoma of the breast II: criteria of operability. Ann Surg 1943;118:859-1032.
3. Rubens R. The management of locally advanced breast cancer. Br J Cancer 1992;65:145-7.
4. Valero V, Buzdar AU, Hortobagyi GN. Locally advanced breast cancer. Oncologist 1996;1:8-17.
5. Hortobagyi GN, Ames F, Buzdar AU, Kau SW, McNeese MD, Paulus D, et al. Management of stage III primary breast cancer with primary chemotherapy, surgery, and radiation therapy. Cancer 1988;62:2507-16.
6. Singletary S, McNeese MD, Hortobagyi GN. Feasibility of breast-conservation surgery after induction chemotherapy for locally advanced breast carcinoma. Cancer 1992;69:2849-52.
7. Ries L, Hankey B, Edwards B. Cancer statistics review, 1983-1987. National Cancer Prevention and Control Surveillance Program, 1989. Bethesda, MD: National Institutes of Health, 1989.
8. Herbsman H, Feldman J, Seldera J, Gardner B, Alfonso AE. Survival following breast cancer surgery in the elderly. Cancer 1981;47:2358-63.
9. Singletary S, Shallenherger R, Guinee V. Breast cancer in the elderly. Ann Surg 1993;218:667-71.
10. Kennedy B. Hormonal therapy in inoperable breast cancer. Cancer 1969;24:1345-9.
11. Campbell FC, Morgan DA, Bishop HM, Benton FM, Blarney RW, Elston CW, et al. The management of locally advanced carcinoma of the breast by Novaldex (tamoxifen): a pilot study. Clin Oncol (R Coll Radiol) 1984;10:111-5.
12. Burn I. Primary endocrine therapy of advanced local breast cancer. Rev Endocrine-Related Cancer 1985;16:5-8.
13. Bradbeer J. Treatment of primary breast cancer in the elderly with "Novaldex" alone. Rev Endocrine-Related Cancer 1985;16:39-42.
14. Kaplan K, Meier P. Nonparametric estimation from incomplete observations. J Am Stat Assoc 1958;53:457-81.
15. Mantel N. Evaluation of survival data and two new rank order statistics rising in its consideration. Cancer Chemother Rep 1966;50:163-70.
16. Boyd S. On oophorectomy in cancer of the breast. BMJ 1990;2:1161-7.
17. Huggins C, Bergenstad D. Inhibition of human mammary and prostatic cancers by adrenalectomy. Cancer Res 1952; 12:134-41.
18. Pearson O, Ray B, Harold C. Hypophysectomy in the treatment of advanced cancer. JAMA 1956;161:17-21.
19. Cole M, Jones C, Todd I. A new antioestrogenic agent in the late breast cancer: an early clinical appraisal of ICI 46474. Br J Cancer 1971;25:270-5.
20. Osborne CK, Boldt DH, Clark GM, Trent JM. Effects of tamoxifen on human breast cancer cell cycle kinetics: accumulation of cells in early G1 phase. Cancer Res 1985;43: 3583-5.
21. Perry R, Kang Y, Greaves B. Effects of tamoxifen on growth and apoptosis of estrogen-dependent and independent human breast cancer cells. Ann Surg Oncol 1995;2:238-45.
22. Kang Y, Cortina R, Perry R. Role of c-myc in tamoxifen-induced apoptosis in estrogen-independent breast cancer cells. 7 Natl Cancer Inst 1996;88:279-83.
23. Early Breast Cancer Trialists' Collaborative Group. Tamoxifen for early breast cancer: an overview of the randomised trials. Lancet 1998;351:1451-67.
24. Early Breast Cancer Trialists' Collaborative Group. Polychemotherapy for early breast cancer: an overview of the randomised trials. Lancet 1998;352:930-42.
25. van Zyl J, Muller A. Tumor excision plus continuous tamoxifen compared with modified radical mastectomy in patients over 70 years of age with operable breast cancer. J Surg Oncol 1995;59:151-4.
26. Bartelink H, Rubens RD, van der Schueren E, Sylvester R. Hormonal therapy prolongs survival in irradiated locally advanced breast cancer: a European Organization for Research and Treatment of Cancer randomized phase III trial. J Clin Oncol 1997;15:207-15.
27. Honig S. Hormonal therapy and chemotherapy. In: Harris J, Lippman M, Morrow M, Hellman S, editors. Diseases of the breast. Philadelphia: Lippincott-Raven, 1996:669-734.
28. Buzdar AU, Singletary S, Booser DJ, Frye DK, Wasaff B, Hortobagyi GN. Combined modality treatment of stage III and inflammatory breast cancer. Surg Oncol Clin N Am 1995;4:715-34.
29. Furr B, Jordan V. The pharmacology and clinical uses of tamoxifen. Pharmacol Ther 1984;25:127-205.
30. Feldman L, Hortobagyi GN, Buzdar AU, Ames FC, Blumenschein GR. Pathological assessment of response to induction chemotherapy in breast cancer. Cancer Res 1986;46: 2578-81.
31. Dixon JM, Love CDB, Tucker S, Bellamy C, Leonard RCF, Miller WR. Letrozole as primary medical therapy for locally advanced and large operable breast cancer [abstract]. Proc Am Soc Clin Oncol 1998;17:104.