Neoadjuvant hormone therapy before radical prostatectomy does not improve disease-specific survival

Current Urology Reports

Volumn 1, Issue 1, 2000, Pages 7-8

  Steiner, Mitchell S ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

Biochemical Recurrence; Flutamide; Prostate Cancer; Prostate Cancer Cell; Radical Prostatectomy

Indexed keywords

ANTINEOPLASTIC HORMONE AGONISTS AND ANTAGONISTS; LEUPRORELIN;

ADJUVANT CHEMOTHERAPY; ARTICLE; HUMAN; MALE; MORTALITY; PREOPERATIVE CARE; PROSTATE TUMOR; PROSTATECTOMY; SURVIVAL RATE;

ANTINEOPLASTIC AGENTS, HORMONAL; CHEMOTHERAPY, ADJUVANT; HUMANS; LEUPROLIDE; MALE; PREOPERATIVE CARE; PROSTATECTOMY; PROSTATIC NEOPLASMS; SURVIVAL RATE;

EID: 0034190984     PISSN: 15272737     EISSN: 15346285     Source Type: Journal    
DOI: 10.1007/s11934-000-0028-y     Document Type: Review

References (8)

1. Steiner MS: Review of peptide growth factors in benign prostatic hyperplasia and urological malignancy. J Urol 1995, 153:1085–1096. DOI: 10.1016/S0022-5347(01)67516-5
2. Fair WR, Aprikian AG, Cohen D, et al.: Use of neoadjuvant androgen deprivation therapy in clinical localized prostate cancer. Clin Invest Med 1993, 16:516–522.
3. Gleave ME, Goldenberg L, Jones EC, et al.: Biochemical and pathological effects of 8 months of neoadjuvant androgen withdrawal therapy before radical prostatectomy in patients with clinically confined prostate cancer. J Urol 1996, 155:213–219. DOI: 10.1016/S0022-5347(01)66598-4
4. Labrie F, Cusan L, Gomez JL, et al.: Down-staging of early stage prostate cancer before radical prostatectomy: the first randomized trial of neoadjuvant combination therapy with flutamide and a luteinizing hormone-releasing hormone agonist. Urology 1994, 44:29–37. DOI: 10.1016/S0090-4295(94)80241-6
5. Pilepich MV, Krall JM, al-Sarraf M, et al.: Androgen deprivation with radiation therapy compared with radiation therapy alone for locally advanced prostatic carcinoma: a randomized comparative trial of the Radiation Therapy Oncology Group. Urology 1995, 45:616–623. DOI: 10.1016/S0090-4295(99)80053-3
6. Soloway MS, Sharifi R, Wajsman Z, et al.: Lupron Depot Neoadjuvant Prostate Study Group: randomized prospective study comparing radical prostatectomy alone versus radical prostatectomy preceded by androgen blockade in clinical stage B2 (T2bNxM) prostate cancer. J Urol 1995, 154:424–428. DOI: 10.1016/S0022-5347(01)67067-8
7. Civantos F, Sadek S, Obek C, et al.: Neoadjuvant hormonal therapy prior to radical prostatectomy. Mol Urol 1999, 3:201–204.
8. Fair WR, Rabbani F, Bastar A, Betancourt J: Neoadjuvant hormone therapy before radical prostatectomy: update on the Memorial Sloan-Kettering Cancer Center Trials. Mol Urol 1999, 3:253–260.