Pulmonary arterial thrombosis in a neonate with homozygous deficiency of antithrombin III: Successful outcome following pulmonary thrombectomy and infusions of antithrombin III concentrate

Cardiology in the Young

Volumn 10, Issue 3, 2000, Pages 275-278

  Roman, K ^a,b   Rosenthal, E ^a   Razavi, R ^a  

^a GUY S HOSPITAL   (United Kingdom)

^b SOUTHAMPTON GENERAL HOSPITAL   (United Kingdom)

Author keywords

Antithrombin III deficiency; Neonatal thrombosis

Indexed keywords

ANTICOAGULANT AGENT; ANTITHROMBIN III;

ANTITHROMBIN III DEFICIENCY; ARTICLE; CASE REPORT; ECHOGRAPHY; FOLLOW UP; GENETICS; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; MALE; MULTIMODALITY CANCER THERAPY; NEWBORN; PATHOLOGY; PULMONARY ARTERY; THROMBECTOMY; THROMBOSIS; TRANSESOPHAGEAL ECHOCARDIOGRAPHY; TREATMENT OUTCOME;

ANTICOAGULANTS; ANTITHROMBIN III; ANTITHROMBIN III DEFICIENCY; COMBINED MODALITY THERAPY; ECHOCARDIOGRAPHY, TRANSESOPHAGEAL; FOLLOW-UP STUDIES; HUMANS; INFANT, NEWBORN; INFUSIONS, INTRAVENOUS; MALE; PULMONARY ARTERY; THROMBECTOMY; THROMBOSIS; TREATMENT OUTCOME;

EID: 0034183350     PISSN: 10479511     EISSN: None     Source Type: Journal    
DOI: 10.1017/s1047951100009240     Document Type: Article

References (9)

1. Lane DA, Olds RJ, Boisclair M, et al. Antithrombin III mutation database: first update. Thromb Haemost, 1993; 70: 361-369.
2. Lane DA, Olds RJ, Conard J, et al. Pleiotropic effects of antithrombin strand 1C substitution mutations. J Clin Invest, 1992; 90: 2422-2433.
3. Lane DA, Auberger K, Ireland H, Roscher AA, Thein SL. Prenatal diagnosis in combined antithrombin and factor V gene mutation. Br J Haematol, 1996; 94: 753-755.
4. Chowdhury V, Lane DA, Mille B, Auberger K, Gandenberger-Bachem S, Pabinger I, Olds RJ, Thein SL. Homozygous antithrombin deficiency: report of two new cases (99 Leu to Phe) associated with arterial and venous thrombosis. Thromb Haemost, 1994; 72: 198-202.
5. Olds RJ, Lane DA, Boisclair M, Sas G, Bock S, Thein SL. Antithrombin Budapest 3: an antithrombin variant with reduced heparin affinity resulting from the substitution L99F. FEBBS Letts, 1992; 300: 241-246.
6. Schmidt BK, Muraji T, Zipursky A. Low antithrombin III in neonatal shock: DIC or non-specific protein depletion? Eur. J Paediatr, 1986; 145:500-503.
7. Bjarke B, Herin P, Blomback M. Neõnatal aortic thrombosis. Acta Paediatr Scand. 1974; 63: 297-301.
8. Sanchez J, Velasco F, Alvarez R, Roman J, Torres A. Aortic thrombosis in a neonate with hereditary antithrombin III deficiency: successful outcome with thrombolytic and replacement treatment. Acta Paediatr 1996: 85:245-247.
9. Peeters S, Vandenplas Y, Jochmans K, Bougatef A, De Waele M, De Wolf D. Myocardial infarction in a neonate with hereditary antithrombin III deficiency. Acta Paediatr. 1993: 82: 610-613.