Is 99mTc human immunoglobulin G scintigraphy (HIG-scan) useful for the detection of spinal inflammation in ankylosing spondylitis?

Clinical and Experimental Rheumatology

Volumn 18, Issue 3, 2000, Pages 379-3382

  De Vlam, Kurt ^a   Van De Wiele, C ^b   Mielants, H ^b   Dierckx, R A ^b   Veys, E M ^b  

^a GHENT UNIVERSITY HOSPITAL   (Belgium)

^b NONE

Author keywords

Ankylosing spondylitis; Immunoglobulin G scintigraphy; Inflammation

Indexed keywords

IMMUNOGLOBULIN G; OXIDRONATE TECHNETIUM TC 99M; TECHNETIUM 99M; DIAGNOSTIC AGENT; DRUG DERIVATIVE; MEDRONATE TECHNETIUM TC 99M; RADIOPHARMACEUTICAL AGENT; TECHNETIUM COMPLEX; TECHNETIUM TC 99M HYDROXYMETHYLENE DIPHOSPHONATE; TECHNETIUM TC 99M POLYCLONAL IGG;

ADULT; AGED; ANKYLOSING SPONDYLITIS; ARTICLE; BACKACHE; CLINICAL ARTICLE; FEMALE; HUMAN; INFLAMMATION; ISOTOPE LABELING; MALE; MUSCLE STIFFNESS; OSTEOARTHRITIS; PRIORITY JOURNAL; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; SPINE SCINTISCANNING; CLINICAL TRIAL; DIFFERENTIAL DIAGNOSIS; METHODOLOGY; MIDDLE AGED; SCINTISCANNING;

ADULT; AGED; DIAGNOSIS, DIFFERENTIAL; FEMALE; HUMANS; IMMUNOGLOBULIN G; MALE; MIDDLE AGED; ORGANOTECHNETIUM COMPOUNDS; OSTEOARTHRITIS; RADIOPHARMACEUTICALS; SPONDYLITIS, ANKYLOSING; TECHNETIUM TC 99M MEDRONATE; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 0034182488     PISSN: 0392856X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. GRAN JT, HUSBY G, HODRVIK M, STORMER J, REMBER-ANDERSEN O: Radiological changes in men and women with ankylosing spondylitis. Ann Rheum Dis 1984; 43: 570-5.
2. WILKINSON M, BYWATERS EGL: Clinical features and course of ankylosing spondylitis. Ann Rheum Dis 1958; 17: 209-28.
3. DE BOIS MHW, PAUWELS EKJ: Arthritis: Current status of scintigraphy and future trends. In: MURRAY IPC and ELL PJ (Eds.): Nuclear Medicine in Clinical Diagnosis and Treatment. Churchill Livingstone, New York, 1994; 1041-50.
4. BREEDVELD FC, VAN KROONENBRUGH MJPG, CAMPS JAJ, FEITSMA HOJ, MARKUSSE HM, PAUWELS EKJ: Imaging of inflammatory arthritis with Technetium-99m-labelled IgG. J Nucl Med 1989; 30: 2017-21.
5. 99mTc human immunoglobulin scintigraphy-a reliable method to detect joint activity in rheumatoid arthritis. J Rheumatol 1992; 19: 1371-6.
6. 99mTc-polyclonal human immunoglobulin G. Nucl Med Commun 1193; 14: 225-31.
7. DE BOIS MHW, WESTEDT ML, ARNDT JW et al.: Technetium-99m-labelled polyclonal human IgG scintigraphy before and 26 weeks after initiation of parenteral gold treatment in patients with rheumatoid arthritis. J Rheumatol 1995; 22: 1461-5.
8. LENTLE BC, RUSSELL AS, PERCY JS, JACKSON FI: Scintigraphic findings in ankylosing spondylitis. J Nucl Med 1977; 18:524-8.
9. LIN MS, FAWCETT HD, GOODWIN DA: Bone scintigraphy demonstrating arthropathy of central joints in ankylosing spondylitis. Clin Nucl Med 1980; 5: 364-6.
10. JACOBSON H, LARSSON SA, VESTERSKÖLD L, LINDVALL N: The application of single photon emission computed tomography to the diagnosis of ankylosing spondylitis of the spine. Br J Radiol 1984; 57: 133-40.
11. RYAN P, CHIKANZA I, GIBSON T, YANNI G, FOGELMAN I: Single photon emission computed tomography and the source of lumbar pain in advanced ankylosing spondylitis. J Clin Rheumatol 1995; 1: 323-7.
12. STOEGER A, MUR E, PENZ-SCHNEEWEISS D et al.: Technetium-99m human immunoglobulin scintigraphy in psoriatic arthropathy: First results. Eur J Nucl Med 1994; 21: 342-4.
13. JUWEID M, STRAUSS HW, YAOITA H, RUBIN RH, FISCHMAN AJ: Accumulation of immunoglobulin G at focal sites of inflammation. Eur J Nucl Med 1992; 19: 159-65.
14. LESLIE WD, THOMSON GT, DUPONT JO, MCDONALD D: Technetium-99m-IgG polyclonal human immunoglobulin scintigraphy in the evaluation of sacroiliitis (letter, comment). Eur J Nucl Med 1996; 23: 1416.
15. SHICHIKAWA K, TSUJIMOTO M, NISHIOKA J, NISHIBAYASHI Y, MATSUMOTO K: Histopathology of early sacroiliitis and enthesitis in ankylosing spondylitis. In ZIFF M and COHEN SB (Eds.): Advances in Inflammatory Research, New York, Raven Press, 1985; 15-24.
16. BERNA L, TORRES G, DIEZ C, ESTORCH M, MARTINEZ-DUNCKER D, CARRIO I: Technetium-99m human polyclonal immunoglobulin G studies and conventional bone scans to detect active joint inflammation in chronic rheumatoid arthritis. Eur J Nucl Med 1992; 19:173-6.
17. SODEN M, ROONEY M, CULLEN A, WHELAN A, FEIGHERY C, BRESHINAN B: Immunohistological features in the synovium obtained from clinically uninvolved knee joints of patients with rheumatoid arthritis. Br J Rheumatol 1989, 28: 287-92.
18. KINNE RW, BECKER W, SIMON G et al.: Joint uptake and body distribution of a technetium-99m-labelled anti-rat-CD4 monoclonal antibody in rat adjuvant arthritis. J Nucl Med 1993, 34: 92-8.
19. ELEWAUT D, DE KEYSER F, VAN DEN BOSH F et al.: Enrichment of T cells carrying beta-7 integrins in inflamed synovial tissue from patients with early spondyloarthropathy, compared to rheumatoid arthritis. J Rheumatol 1998, 25: 1932-7.