Feasibility of oral ciprofloxacin for the outpatient management of febrile neutropenia in selected children with cancer

Cancer

Volumn 88, Issue 7, 2000, Pages 1710-1714

  Aquino, Victor M ^a   Herrera, Larry ^b   Sandler, Eric S ^b   Buchanan, George R ^b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b NONE

Author keywords

Ambulatory care; Ciprofloxacin; Fever; Neutropenia; Oncology; Pediatrics

Indexed keywords

ACICLOVIR; ANTINEOPLASTIC AGENT; CEFTAZIDIME; CIPROFLOXACIN; PARACETAMOL;

ADOLESCENT; ADULT; AGE; ANTIBIOTIC THERAPY; ARTICLE; CANCER REGRESSION; CELL COUNT; CHILD; CHILDHOOD CANCER; CLINICAL ARTICLE; FEASIBILITY STUDY; FEBRILE NEUTROPENIA; FEMALE; FEVER; HERPES ZOSTER; HUMAN; INFANT; MALE; OUTPATIENT CARE; PHAGOCYTE; PRIORITY JOURNAL; TREATMENT OUTCOME;

ADMINISTRATION, ORAL; ADOLESCENT; ADULT; AMBULATORY CARE; ANTI-INFECTIVE AGENTS; BLOOD CELL COUNT; CHILD; CHILD, PRESCHOOL; CIPROFLOXACIN; FEASIBILITY STUDIES; FEMALE; HUMANS; LEUKEMIA; MALE; NEOPLASMS; NEUTROPENIA;

EID: 0034176384     PISSN: 0008543X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0142(20000401)88:7<1710::AID-CNCR27>3.0.CO;2-1     Document Type: Article

References (34)

1. Pizzo PA, Robichaud KJ, Wesley R, Commers JR. Fever in the pediatric and young adult patient with cancer. A prospective study of 1001 episodes. Medicine 1982;61:153-65.
2. Pizzo PA, Robichaud KJ, Gill FA, Witebsky FG, Levine AS, Deisseroth AB, et al. Duration of empiric antibiotic therapy in granulocytopenic patients with cancer. Am J Med 1979; 67:194-200.
3. Bodey GP. Antibiotics in patients with neutropenia. Arch Intern Med 1984;144:1845-51.
4. Schimpff SC. Empiric antibiotic therapy for granulocytopenic patients. Am J Med 1986;80(Suppl 5C):13-20.
5. Hughes WT, Armstrong D, Bodey GP, Feld R, Mandell GL, Meyers JD, et al. Guidelines for the use of antimicrobial agents in neutropenic patients with unexplained fever. J Infect Dis 1990;161:381-96.
6. Barson WJ, Brady MJ. Management of infections in children with cancer. Hematol Oncol Clin North Am 1987;1:801-39.
7. Rubin M, Hathorn JW, Pizzo PA. Controversies in the management of febrile neutropenic cancer patients. Cancer Invest 1988;6:167-84.
8. Nachman JB, Honig GR. Fever and neutropenia in children with neoplastic disease. An analysis of 158 episodes. Cancer 1980;45:407-12.
9. Kaplan AH, Weber DJ, Daves L, Israel F, Wells RJ. Short courses of antibiotics in selected febrile neutropenic patients. Am J Med Sci 1991;302:353-4.
10. Tomiak AT, Yan JC, Huan HD, Cripps MC, Goel R, Perrault DJ, et al. Duration of intravenous antibiotics for patients with neutropenic fever. Ann Oncol 1994;5:441-5.
11. Jones GR, Konsler GK, Dunaway RP, Gold SH, Cooper HA, Wells RJ. Risk factors for recurrent fever after the discontinuation of empiric antibiotic therapy for fever and neutropenia in pediatric patients with a malignancy or hematologic condition. J Pediatr 1994;124:702-9.
12. Bash RO, Katz JA, Cash JV, Buchanan GR. Safety and cost effectiveness of early hospital discharge of lower risk children with cancer admitted for fever and neutropenia. Cancer 1994;74(1):189-96.
13. Aquino VM, Tkczewski I, Buchanan G. Early discharge of the low-risk febrile neutropenic child with cancer. Clin Infect Dis 1997;20:163-5.
14. Talcott JA, Finberg R, Meyer FH, Goldman L. The medical course of cancer patients with fever and neutropenia. Clinical identification of a low risk subgroup at presentation. Arch Intern Med 1988;148:2561-8.
15. Rubenstein RB, Rolston K, Benjamin RS, Loewy J, Escalante C, Manzullo E, et al. Outpatient treatment of febrile episodes in low-risk neutropenic patients with cancer. Cancer 1993;71:3640-6.
16. Rolston K, Rubenstein EB, Risbee-Hume S, et al. Outpatient treatment of febrile episodes in low-risk neutropenic cancer patients. Proc Am Soc Clin Oncol 1993;13:436.
17. Malik IA, Khan WA, Aziz Z, Karim M. Self-administered antibiotic therapy for chemotherapy-induced, low-risk febrile neutropenia in patients with nonhematologic neoplasms. Clin Infect Dis 1994;19:522-7.
18. Mustafa MM, Aquino VM, Pappo A, Tkaczewski I, Buchanan GR. A pilot study of outpatient management of febrile neutropenic children with cancer who are at low risk of bacteremia. J Pediatr 1996;128:847-9.
19. Rackoff WR, Gonin R, Robinson C, Kriessman SG, Breitfeld PP. Predicting the risk of bacteremia in children with fever and neutropenia. J Clin Oncol 1996;14(3):919-24.
20. Lucas KG, Brown AE, Armstrong D, Chapman D, Heller G. The identification of febrile, neutropenic children with neoplastic disease at low risk for bacteremia and complications of sepsis. Cancer 1996;77(4):791-8.
21. The Immunocompromised Host Society. The design, analysis and reporting of clinical trails on the empiric antibiotic management of the neutropenic patient. Chemotherapy 1990;40:398-410.
22. Zar JH. Biostatistical analysis. Upper Saddle River, NJ: Prentice-Hall, Inc., 1996.
23. Steiver HG, Telfor GO, Mossey JM. Intravenous antibiotic therapy at home. Ann Intern Med 1978;87(Suppl):46-8.
24. Smego RA, Gainer RB. Home intravenous antimicrobial therapy provided by a community hospital and a university hospital. Am J Hosp Pharm 1989;42:2185-9.
25. Rehm SJ, Weinstein AJ. Home intravenous antibiotic therapy: a team approach. Ann Intern Med 1983;99:388-92.
26. Portez DM, Woodard D. Outpatient use of ceftriaxone: a cost-benefit analysis. Am J Med 1984;77(Suppl 5):316-22.
27. Malik IA, Khan WA, Karim M, Aziz Z, Khan MA. Feasibility of outpatient management of fever in cancer patients with low-risk neutropenia: results of a prospective randomized trial. Am J Med 1995;98:224-31.
28. Kubin R. Safety and efficacy of ciprofloxacin in paediatric patients - review. Infection 1993;21:413-21.
29. Rozenberg-Arska M, Dekker AW, Verhoef J. Ciprofloxacin for selective decontamination of the alimentary tract in patients with acute leukemia during remission/induction treatment. J Infect Dis 1987;106:104-7.
30. Schaad UB. Use of new quinolones in pediatrics. Isr J Med Sci 1994;30:463-8.
31. Bergan T, Thorsteinsson SB, Cunningham C. Pharmacokinetics of ciprofloxacin. J Antimicrob Chemother 1987; 82(Suppl 4A):97-102.
32. Stahlman R, Herker HJ, Hinz N. Ofloxacin in juvenile non-human primates and rats: arthropathy and drug plasma concentrations. Arch Toxicol 1990;64:193-204.
33. Chyshky V. Ciprofloxacin in children: worldwide clinical experience. Infection 1991;19:289-96.
34. Hoffman K, Eprechins B. Joint lesions induced by quinolones - differences between clinical, MRI and post mortem findings. Presented at the 3rd International Symposium on New Quinolones, Vancouver, British Columbia, 1990:a461.