The current state of citicoline in cerebral ischemia;Estado actual de la citicolina en la isquemia cerebral

Revista de Neurologia

Volumn 30, Issue 7, 2000, Pages 663-670

  Abad Santos, F ^a  

^a HOSPITAL UNIVERSITARIO DE LA PRINCESA   (Spain)

Author keywords

CDP coline; Cerebral ischemia; Cerebrovascular disorders; Citicoline; Clinical trials; Review; Stroke

Indexed keywords

CITICOLINE;

ARTICLE; BRAIN BLOOD FLOW; BRAIN ISCHEMIA; CEREBROVASCULAR DISEASE; DRUG EFFECT; DRUG EFFICACY; DRUG SAFETY; HUMAN; NERVE MEMBRANE; NEUROPROTECTION; POPULATION RESEARCH;

EID: 0034174136     PISSN: 02100010     EISSN: None     Source Type: Journal    
DOI: 10.33588/rn.3007.2000032     Document Type: Article

References (12)

1. García-Mas A, Rossinol A, Roca M, Lozano R, Rosselló J, Llinàs J. Effects of citicoline in subcortical dementia associated with Parkinson's disease assessed by quantified electroencephalography. Clin Ther 1992; 14: 718-29.
2. 14C CDP-choline. Arzneimittelforschung 1983; 33: 1066-70.
3. De la Morena E. Efficacy of CDP-choline in the treatment of senile alterations in memory. Ann N Y Acad Sci 1991; 640: 233-6.
4. Secades JJ, Frontera G. CDP-choline: pharmacological and clinical review. Methods Find Exp Clin Pharmacol 1995; 14 (Suppl B): 2-54.
5. Agut J, López-Coviella I, Ortiz JA, Wurtman RJ. Oral cytidine 5′-diphosphate choline administration to rats increases brain phospholipid levels. Ann N Y Acad Sci 1993; 695: 318-20.
6. Weiss GB. Metabolism and actions of CDP-choline as an endogenous compound and administered exogenously as citicoline. Life Sci 1995; 56: 637-60.
7. 14C-Methyl CDP-choline. Arzneimittelforschung 1983; 33: 1048-50.
8. Yatsu FM, Mosa SA. Brain lipid changes following hypoxia. Stroke 1971; 2: 587-93.
9. Trovarelli G, DeMedio GE, Dorman RV, Piccinin GL, Horrocks LA, Porcellati G. Effect of cytidine diphosphate choline (CDP-choline) on ischemia-induced alterations of brain lipid in the gerbil. Neurochem Res 1981; 6: 821-33.
10. Dorman RV, Dabrowiecki Z, Horrocks LA. Effects of CDP-choline and CDP-ethanolamine on the alterations in rat brain lipid metabolism induced by global ischemia. J Neurochem 1983; 40: 276-9.
11. Arrigoni E, Averet N, Cohadon F. Effects of CDP-choline of phospholipase and cholinephosphotransferase activities following a cryogenic brain injury in the rabbit. Biochem Pharmacol 1987; 36: 3697-700.
12. Spagnoli A, Tognoni G. 'Cerebroactive' drugs: clinical pharmacology and therapeutic role in cerebrovascular disorders. Drugs 1983; 26: 44-69.