In vitro cytotoxic effect of N-(phosphonacetyl)-L-aspartic acid in liposome against C-26 murine colon carcinoma

Archives of Pharmacal Research

Volumn 23, Issue 2, 2000, Pages 167-171

  Kim, Jin Seok ^a   Heath, Timothy D ^b  

^a Sookmyung Women's University   (South Korea)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

C 26 Murine Colon Carcinoma; Cytotoxicity; Liposomes; PALA

Indexed keywords

ANTINEOPLASTIC AGENT; ASPARTIC ACID; DRUG CARRIER; DRUG DERIVATIVE; LIPOSOME; PHOSPHONOACETIC ACID; SPARFOSIC ACID;

ANIMAL; ARTICLE; CELL CULTURE; COLON TUMOR; MOUSE; PARTICLE SIZE; PATHOLOGY;

ANIMALS; ANTINEOPLASTIC AGENTS; ASPARTIC ACID; COLONIC NEOPLASMS; DRUG CARRIERS; LIPOSOMES; MICE; PARTICLE SIZE; PHOSPHONOACETIC ACID; TUMOR CELLS, CULTURED;

EID: 0034169408     PISSN: 02536269     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02975508     Document Type: Article

References (26)

1. Bartlett, G. R., Phosphorus assay in column chromatography, J. Biol. Chem., 234, 466-468 (1958).
2. Bligh, E. G. and Dyer. W. J., A rapid method of total lipid extraction and purification. Can. J. Biochem. Physiol., 37, 911-917 (1959).
3. Boman, N. L., Masin, D., Mayer, L. D., Cullis, P. R. and Bally, M. B., Liposomal vincristine which exhibits increased drug retention and increased circulation longevity cures mice bearing p388 tumors. Cancer Res., 54, 2830-2833 (1994).
4. Daoud, S. S., Fetouh, M. I. and Giovanella, B. C., Antitumor effect of liposome-incorporated camptothecin in human malignant xenografts. Anti-Cancer Drugs, 6, 83-93 (1995).
5. Grem, J. L., King, S. A., O'Dwyer, P. J. and Leyland-Jones, B., Biochemistry and clinical activity if N-(phosphonacetyl)-L-aspartate: A review. Cancer Res., 48, 4441-4454 (1988).
6. Heath, T. D., Montgomery, J. A., Piper, J. R and Papahadjopoulos, D., Antibody-targeted liposomes: Increase in specific toxicity of methotrexate-γ-aspartate. Proc. Natl. Acad. Sci., USA, 80, 1377-1381 (1983).
7. Heath, T. D., Lopez, N. C. and Papahadjopoulos, D., The effects of liposome size and surface charge on liposome-mediated delivery of methotrexate-γ-aspartate to cells in vitro. Biochim. Biophys. Acta, 820, 74-84 (1985a).
8. Heath, T. D., Lopez, N. G., Stem, W. H. and Papahadjopoulos, D., 5-Fluoroorotate: a new liposome-dependent cytotoxic agent. FEBS Lett., 187, 73-75 (1985b).
9. Heath, T. D. and Brown, C. S. Liposome dependent delivery of N-(phosphonacetyl) -L-aspartic acid to cells in vitro. J. Liposome Res., 1, 303-317 (1989).
10. Loo, T. L., Friedman, J., Moore, E. C., Valdivieso, M., Marti, J. R. and Stewart, D., Pharmacological disposition of N-(phosphonacetyl)-L-aspartate in humans. Cancer Res., 40, 86-90 (1980).
11. Maruyama, K., Unezaki, S., Yuda, S., Ishida, O., Suginaka, A., Huang, L. and Iwatsuru, M., Enhanced delivery and antitumor effect of doxorubicin encapsulated in long-circulating liposomes, J. Liposome Res., 4, 143-165 (1994).
12. Mayer, L. D., Hope, M. J. and Cullis, P. R., Vesicles of variable sizes produced by a rapid extrusion procedure, Biochim. Biophys. Acta., 858, 161-168 (1986).
13. Mayhew, E., Cimino, M., Klemperer, J., Lazo, R., Wiemikowski, J. and Arbuck, S., Free and liposomal doxorubicin treatment of intraperitoneal colon 26 tumor: Therapeutic and pharmacologic studies. Selective Cancer Therapeutics, 6, 193-209 (1990).
14. Monkkonen, J. and Heath, T. D., The effects of liposome-encapsulated and free clondronate on the growth of macrophage-like cells in vitro: The role of calcium and iron, Calcif. Tissue Int., 53, 139-146 (1993a).
15. Monkkonen, J., Brown, C. S., Thompson, T. T. and Heath, T. D., Liposome-mediated delivery of gallium to macrophage-like cells in vitro: Demonstration of a transferrin-independent route for intracellular delivery of metal ions. Pharm. Res., 10, 1130-1135 (1993b).
16. Olson, F., Hunt, C. A., Szoka, F. C., Vail, W. J. and Papahadjopoulos, D., Preparation of liposomes of defined size distribution by extrusion through polycarbonate membrane. Biochim. Biophys. Acta., 557, 9-23 (1979).
17. Papahadjopoulos, D., Allen, T. M., Gabizon, A., Mayhew, E., Matthay, K. K., Huang, S. K., Lee, K-D., Woodle, M. C., Lasic, D. D., Redemann, C. and Martin, F. J., Sterically stabilized liposomes: Improvements in pharmacokinetics and antitumor therapeutic efficacy. Proc. Natl. Acad. Sci., USA, 88, 11460-11464 (1991).
18. Rustum, Y., Dave, C., Mayhew, E. and Papahadjopoulos, D., Role of Liposome type and route of administration in the antitumor activity of liposome-entrapped 1-beta-D-arabinofuranosylcytosine against mouse L 1210 leukemia. Cancer Res., 39, 1390-1395 (1979).
19. Sechoy, O., Vidal, M., Philippot, J. R. and Bienvenue, A., Interactions of human lymphoblasts with targeted vesicles containing Sendai virus envelope proteins. Exp. Cell Res., 122-131 (1989).
20. Senior, J. H., Fate and behavior of liposomes in vivo: a review of controlling factors Crit. Rev. Ther. Drug Carrier System, 3, 123-193 (1987).
21. Sharma, A., Straubinger, N. L., Straubinger, R. M., Modulation of human ovarian tumor cell sensitivity to N-(phosphonacetyl)-L-aspartate by liposome drug carriers. Pharm. Res., 10, 1434-1441 (1993).
22. Sur, B., Ray, R. R., Sur, P. and Roy, D. K., Effect of liposomal encapsulation of cis-platinum diamminedichloride in the treatment of Ehrlich ascites carcinoma. Oncology, 40, 372-376 (1983).
23. Szoka, F. and Papahadjopoulos, D., Procedure for preparation of liposomes with large internal aqueous space and high capture by reverse-phase evaporation. Proc. Natl. Acad. Sci., USA, 75, 4194-4198 (1978).
24. Szoka, F., Olson, F., Heath, T., Vail, W., Mayhew, E. and Papahadjopoulos, D., Preparation of unilamellar liposomes of intermediate size (0. 1-0.2 μm) by a combination of reverse phase evaporation and extrusion through polycarbonate membranes. Biochim. Biophys. Acta., 601, 559-571 (1980).
25. Vaage, J., Donovan, D., Mayhew, E., Uster, P. and Woodle, M., Therapy of mouse mammary carcinomas with vincristine and doxorubicin encapsulated in sterically stabilized liposomes. Int. J. Cancer, 54, 959-964 (1993).
26. Williams, S. S., Alosco, T. R., Mayhew, E., Lasic, D. D., Martin, F. J. and Bankert, R. B., Arrest of human lung tumor xenograft growth in severe combined immunodeficient mice using doxorubicin encapsulated in sterically stabilized liposomes. Cancer Res., 53, 3964-3967 (1993).