메뉴 건너뛰기




Volumn 95, Issue 5, 2000, Pages 1827-1833

Fetal expression of a human Aγ globin transgene rescues globin chain imbalance but not hemolysis in EKLF null mouse embryos

Author keywords

[No Author keywords available]

Indexed keywords

BETA GLOBIN; ERYTHROID KRUPPEL LIKE FACTOR; GAMMA GLOBIN; HEMOGLOBIN;

EID: 0034161376     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v95.5.1827.004k10_1827_1833     Document Type: Article
Times cited : (44)

References (30)
  • 1
    • 0013974622 scopus 로고
    • Thalassemia: The consequences of unbalanced hemoglobin synthesis
    • Nathan DG, Gunn RB. Thalassemia: the consequences of unbalanced hemoglobin synthesis. Am J Med. 1966;41:815.
    • (1966) Am J Med. , vol.41 , pp. 815
    • Nathan, D.G.1    Gunn, R.B.2
  • 2
    • 0027211845 scopus 로고
    • A novel, erythroid cell-specific murine transcription factor that binds to the CACCC element and is related to the Kruppel family of nuclear proteins
    • Miller IJ, Bieker JJ. A novel, erythroid cell-specific murine transcription factor that binds to the CACCC element and is related to the Kruppel family of nuclear proteins. Mol Cell Biol. 1993;13:2776.
    • (1993) Mol Cell Biol. , vol.13 , pp. 2776
    • Miller, I.J.1    Bieker, J.J.2
  • 3
    • 0028174097 scopus 로고
    • Analyses of beta-thalassemia mutant DNA interactions with erythroid Kruppel-like factor (EKLF), an erythroid cell-specific transcription factor
    • Feng WC, Southwood CM, Bieker JJ. Analyses of beta-thalassemia mutant DNA interactions with erythroid Kruppel-like factor (EKLF), an erythroid cell-specific transcription factor. J Biol Chem. 1994;269:1493.
    • (1994) J Biol Chem. , vol.269 , pp. 1493
    • Feng, W.C.1    Southwood, C.M.2    Bieker, J.J.3
  • 4
    • 0028936440 scopus 로고
    • Role of erythroid Kruppel-like factor in human gamma- to beta-globin gene switching
    • Donze D, Townes TM, Bieker JJ. Role of erythroid Kruppel-like factor in human gamma- to beta-globin gene switching. J Biol Chem. 1995;270:1955.
    • (1995) J Biol Chem. , vol.270 , pp. 1955
    • Donze, D.1    Townes, T.M.2    Bieker, J.J.3
  • 5
    • 0028990264 scopus 로고
    • Lethal beta-thalassaemia in mice lacking the erythroid CACCC-transcription factor EKLF
    • Perkins AC, Sharpe AH, Orkin SH. Lethal beta-thalassaemia in mice lacking the erythroid CACCC-transcription factor EKLF. Nature. 1995;375:318.
    • (1995) Nature , vol.375 , pp. 318
    • Perkins, A.C.1    Sharpe, A.H.2    Orkin, S.H.3
  • 6
    • 0029010790 scopus 로고
    • Defective haematopoiesis in fetal liver resulting from inactivation of the EKLF gene
    • Nuez B, Michalovich D, Bygrave A, Ploemacher R, Grosveld F. Defective haematopoiesis in fetal liver resulting from inactivation of the EKLF gene. Nature. 1995;375:316.
    • (1995) Nature , vol.375 , pp. 316
    • Nuez, B.1    Michalovich, D.2    Bygrave, A.3    Ploemacher, R.4    Grosveld, F.5
  • 8
    • 0029864417 scopus 로고    scopus 로고
    • Functional interaction of GATA1 with erythroid Kruppel-like factor and Sp1 at defined erythroid promoters
    • Gregory RC, Taxman DJ, Seshasayee D, Kensinger MH, Bieker JJ, Wojchowski DM. Functional interaction of GATA1 with erythroid Kruppel-like factor and Sp1 at defined erythroid promoters. Blood. 1996;87:1793.
    • (1996) Blood , vol.87 , pp. 1793
    • Gregory, R.C.1    Taxman, D.J.2    Seshasayee, D.3    Kensinger, M.H.4    Bieker, J.J.5    Wojchowski, D.M.6
  • 9
    • 0027515934 scopus 로고
    • Erythroid regulatory elements
    • Raich N, Romeo PH. Erythroid regulatory elements. Stem Cells. 1993;11:95.
    • (1993) Stem Cells , vol.11 , pp. 95
    • Raich, N.1    Romeo, P.H.2
  • 10
    • 0029861514 scopus 로고    scopus 로고
    • Silencing of human fetal globin expression is impaired in the absence of the adult beta-globin gene activator protein EKLF
    • Perkins AC, Gaensler KM, Orkin SH. Silencing of human fetal globin expression is impaired in the absence of the adult beta-globin gene activator protein EKLF. Proc Natl Acad Sci U S A. 1996;93:12,267.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 12267
    • Perkins, A.C.1    Gaensler, K.M.2    Orkin, S.H.3
  • 11
    • 0029829779 scopus 로고    scopus 로고
    • The role of EKLF in human beta-globin gene competition
    • Wijgerde M, Gribnau J, Trimborn T, et al. The role of EKLF in human beta-globin gene competition. Genes Dev. 1996;10:2894.
    • (1996) Genes Dev. , vol.10 , pp. 2894
    • Wijgerde, M.1    Gribnau, J.2    Trimborn, T.3
  • 12
  • 13
    • 0024635998 scopus 로고
    • A single erythroid-specific DNase I super-hypersensitive site activates high levels of human beta-globin gene expression in transgenic mice
    • Ryan TM, Behringer RR, Martin NC, Townes TM, Palmiter RD, Brinster RL. A single erythroid-specific DNase I super-hypersensitive site activates high levels of human beta-globin gene expression in transgenic mice. Genes Dev. 1989;3:314.
    • (1989) Genes Dev. , vol.3 , pp. 314
    • Ryan, T.M.1    Behringer, R.R.2    Martin, N.C.3    Townes, T.M.4    Palmiter, R.D.5    Brinster, R.L.6
  • 14
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanatephenol-chloroform extraction
    • Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanatephenol-chloroform extraction. Anal Biochem. 1987;162:156.
    • (1987) Anal Biochem. , vol.162 , pp. 156
    • Chomczynski, P.1    Sacchi, N.2
  • 15
    • 0022497172 scopus 로고
    • Rapid reprogramming of globin gene expression in transient heterokaryons
    • Baron MH, Maniatis T. Rapid reprogramming of globin gene expression in transient heterokaryons. Cell. 1986;46:591.
    • (1986) Cell , vol.46 , pp. 591
    • Baron, M.H.1    Maniatis, T.2
  • 16
    • 0029050860 scopus 로고
    • Erythropoiesis and globin gene expression in mice lacking the transcription factor NF-E2
    • Shivdasani RA, Orkin SH. Erythropoiesis and globin gene expression in mice lacking the transcription factor NF-E2. Proc Natl Acad Sci U S A. 1995;92:8690.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 8690
    • Shivdasani, R.A.1    Orkin, S.H.2
  • 17
    • 0031026036 scopus 로고    scopus 로고
    • Characterization of adult alpha- and beta-globin genes in the zebrafish
    • Chan FY, Robinson J, Brownlie A, et al. Characterization of adult alpha- and beta-globin genes in the zebrafish. Blood. 1997;89:688.
    • (1997) Blood , vol.89 , pp. 688
    • Chan, F.Y.1    Robinson, J.2    Brownlie, A.3
  • 18
    • 0027325474 scopus 로고
    • Expediting rare variant hemoglobin characterization by combined HPLC/electrospray mass spectrometry
    • Witkowska HE, Bitsch F, Shackleton CH. Expediting rare variant hemoglobin characterization by combined HPLC/electrospray mass spectrometry. Hemoglobin. 1993;17:227.
    • (1993) Hemoglobin , vol.17 , pp. 227
    • Witkowska, H.E.1    Bitsch, F.2    Shackleton, C.H.3
  • 19
    • 0021286911 scopus 로고
    • High performance liquid chromatographic separation of globins on a large-pore C4 column
    • Shelton JB, Shelton JR, Schroeder WA. High performance liquid chromatographic separation of globins on a large-pore C4 column. J Liquid Chromatogr. 1984;7:1969-1997.
    • (1984) J Liquid Chromatogr. , vol.7 , pp. 1969-1997
    • Shelton, J.B.1    Shelton, J.R.2    Schroeder, W.A.3
  • 21
    • 0030788718 scopus 로고    scopus 로고
    • -/- adult erythrocytes, due to a deficiency of beta-globin chains, is ameliorated by human gamma-globin chains
    • -/- adult erythrocytes, due to a deficiency of beta-globin chains, is ameliorated by human gamma-globin chains. Blood. 1997;90:1291.
    • (1997) Blood , vol.90 , pp. 1291
    • Lim, S.K.1    Bieker, J.J.2    Lin, C.S.3    Costantini, F.4
  • 22
    • 0027514570 scopus 로고
    • Discrimination among potential activators of the beta-globin CACCC element by correlation of binding and transcriptional properties
    • Hartzog GA, Myers RM. Discrimination among potential activators of the beta-globin CACCC element by correlation of binding and transcriptional properties. Mol Cell Biol. 1993;13:44.
    • (1993) Mol Cell Biol. , vol.13 , pp. 44
    • Hartzog, G.A.1    Myers, R.M.2
  • 23
    • 0029864889 scopus 로고    scopus 로고
    • Isolation and characterization of the cDNA encoding BKLF/TEF-2, a major CACCC-box-binding protein in erythroid cells and selected other cells
    • Crossley M, Whitelaw E, Perkins A, Williams G, Fujiwara Y, Orkin SH. Isolation and characterization of the cDNA encoding BKLF/TEF-2, a major CACCC-box-binding protein in erythroid cells and selected other cells. Mol Cell Biol. 1996;16:1695.
    • (1996) Mol Cell Biol. , vol.16 , pp. 1695
    • Crossley, M.1    Whitelaw, E.2    Perkins, A.3    Williams, G.4    Fujiwara, Y.5    Orkin, S.H.6
  • 24
    • 0029926485 scopus 로고    scopus 로고
    • Arrested development of embryonic red cell precursors in mouse embryos lacking transcription factor GATA-1
    • Fujiwara Y, Browne CP, Cunniff K, Goff SC, Orkin SH. Arrested development of embryonic red cell precursors in mouse embryos lacking transcription factor GATA-1. Proc Natl Acad Sci U S A. 1996;93:12,355.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 12355
    • Fujiwara, Y.1    Browne, C.P.2    Cunniff, K.3    Goff, S.C.4    Orkin, S.H.5
  • 25
    • 0030685130 scopus 로고    scopus 로고
    • Transcriptional regulation of the human erythroid 5-aminolevulinate synthase gene: Identification of promoter elements and role of regulatory proteins
    • Surinya KH, Cox TC, May BK. Transcriptional regulation of the human erythroid 5-aminolevulinate synthase gene: identification of promoter elements and role of regulatory proteins. J Biol Chem. 1997;272:26,585.
    • (1997) J Biol Chem. , vol.272 , pp. 26585
    • Surinya, K.H.1    Cox, T.C.2    May, B.K.3
  • 26
    • 0032007291 scopus 로고    scopus 로고
    • Deficient heme and globin synthesis in embryonic stem cells lacking the erythroid-specific delta-aminolevulinate synthase gene
    • Harigae H, Suwabe N, Weinstock PH, et al. Deficient heme and globin synthesis in embryonic stem cells lacking the erythroid-specific delta-aminolevulinate synthase gene. Blood. 1998;91:798.
    • (1998) Blood , vol.91 , pp. 798
    • Harigae, H.1    Suwabe, N.2    Weinstock, P.H.3
  • 27
    • 0031735118 scopus 로고    scopus 로고
    • Positional cloning of the zebrafish sauternes gene: A model for congenital sideroblastic anaemia
    • see comments
    • Brownlie A, Donovan A, Pratt SJ, et al. Positional cloning of the zebrafish sauternes gene: a model for congenital sideroblastic anaemia [see comments]. Nat Genet. 1998;20:244.
    • (1998) Nat Genet. , vol.20 , pp. 244
    • Brownlie, A.1    Donovan, A.2    Pratt, S.J.3
  • 28
    • 0019305526 scopus 로고
    • Inherited hemolytic disease in mice: A review and update
    • Bernstein SE. Inherited hemolytic disease in mice: a review and update. Lab Anim Sci. 1980;30:197.
    • (1980) Lab Anim Sci. , vol.30 , pp. 197
    • Bernstein, S.E.1
  • 29
    • 0021704597 scopus 로고
    • Spectrin deficient inherited hemolytic anemias in the mouse: Characterization by spectrin synthesis and mRNA activity in reticulocytes
    • Bodine DMT, Birkenmeier CS, Barker JE. Spectrin deficient inherited hemolytic anemias in the mouse: characterization by spectrin synthesis and mRNA activity in reticulocytes. Cell. 1984;37:721.
    • (1984) Cell , vol.37 , pp. 721
    • Bodine, D.M.T.1    Birkenmeier, C.S.2    Barker, J.E.3
  • 30
    • 0029010312 scopus 로고
    • Identification and functional characterization of an erythroid-specific enhancer in the L-type pyruvate kinase gene
    • Lacronique V, Lopez S, Miquerol L, Porteu A, Kahn A, Raymondjean M. Identification and functional characterization of an erythroid-specific enhancer in the L-type pyruvate kinase gene. J Biol Chem. 1995;270:14,989.
    • (1995) J Biol Chem. , vol.270 , pp. 14989
    • Lacronique, V.1    Lopez, S.2    Miquerol, L.3    Porteu, A.4    Kahn, A.5    Raymondjean, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.