Structures of m-iodo Hoechst-DNA complexes in crystals with reduced solvent content: Implications for minor groove binder drug design

Nucleic Acids Research

Volumn 28, Issue 5, 2000, Pages 1252-1258

  Squire, Christopher J ^c,e   Baker, L J ^d,e   Clark, George R ^e   Martin, Roger F ^a   White, Jonathan ^b  

^a PETER MACCALLUM CANCER CENTRE   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c RUTGERS UNIVERSITY   (United States)

^d INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

4 [5 (4 METHYL 1 PIPERAZINYL)[2,5' BI 1H BENZIMIDAZOL] 2' YL]PHENOL; ADENOSINE; CYTOSINE; DNA; GUANINE; HYDROGEN; IODINE DERIVATIVE; LIGAND; MAGNESIUM ION; OLIGONUCLEOTIDE; OXYGEN; PHOSPHATE; PHOTOSENSITIZING AGENT; POLYMER; SOLVENT; THYMINE;

ARTICLE; CELL VOLUME; CONTROLLED STUDY; CRYSTAL STRUCTURE; DEHYDRATION; DNA CLEAVAGE; DNA CONFORMATION; DNA CROSS LINKING; DNA DRUG COMPLEX; DRUG DESIGN; LIGAND BINDING; PHOTOSENSITIZATION; PRIORITY JOURNAL; SOLUTION AND SOLUBILITY; X RAY DIFFRACTION;

EID: 0034160064     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/28.5.1252     Document Type: Article

References (29)

1. Hutchinson, F. and Kohnlein, W. (1980) Prog. Mol. Subcell. Biol., 7, 1-42
2. McGinn, C.J. and Kinsella, T.J. (1993) Curr. Probl. Cancer Res., 17, 273-320.
3. Martin, R.F., Murray, V., D'Cunha, G., Pardee, M., Kampouris, E., Haigh, A., Kelly, D.P. and Hodgson, G.S. (1990) Int. J. Radiat. Biol., 57, 939-946.
4. Martin, R.F., Kelly, D.P., Roberts, M., Green, A., Denison, L., Rose, M., Reum, M. and Pardee, M. (1994) Int. J. Radiat. Oncol. Biol. Phys., 29, 549-553.
5. Kelly, D.P., Bateman, S.A., Hook, R.J., Martin, R.F., Reum, M.E., Rose, M. and Whittaker, A.R.D. (1994) Aust. J. Chem., 47, 1751-1769.
6. Salunke, D.M., Veerapandian, B., Kodandapani, R. and Vijayan, M. (1985) Acta Crystallogr., B41, 431-436.
7. Siemens (1994) SMART & SAINT. Siemens Analytical Instruments Inc., Madison, WI.
8. Blessing, R.H. (1995) Acta Crystallogr., A51, 33-38.
9. Siemens (1994) SHELXTL (XPREP). Siemens Analytical Instruments Inc., Madison, WI.
10. Westhof, E. (1987) J. Biomol. Struct. Dyn., 5, 581-600.
11. Brunger, A.T. (1997) Nature Struct. Biol., 4 (suppl.), 862-865.
12. Navaza, J. (1994) Acta Crystallogr., A50, 157-163.
13. Clark, G.R., Squire, C.J., Gray, E.J., Leupin, W. and Neidle, S. (1996) Nucleic Acids Res., 24, 4882-4889.
14. Jones, T.A. and Kjeldgaard, M. (1995) O version 5.10. Uppsala University, Uppsala, Sweden.
15. Biosym Technologies (1993) Insight II version 2.3.0. Molecular Simulations Inc., San Diego, CA.
16. Squire, C.J., Clark, G.R. and Denny, W.A. (1997) Nucleic Acids Res., 25, 4072-4078.
17. Sheldrick, G.M. (1997) SHELXL97. Program for the Solution of Crystal Structures. Universität Göttingen, Göttingen, Germany.
18. Vega, M.C., Garcia-Saez, I., Aymami, J., Eritja, R., van der Marel, G.A., van Boom, J.H., Rich, A. and Coll, M. (1994) Eur. J. Biochem., 222, 721-726.
19. Carrondo, M.A., Coll, M., Aymami, J., Wang, A.H., van der Marel, G.A., van Boom, J.H. and Rich, A. (1989) Biochemistry, 28, 7849-7859.
20. Sriram, M., Van Der Marel, G.A., Roelen, H.L.P.F., Van Boom, J.H. and Wang, A.H.-J. (1992) EMBO J., 11, 225-232.
21. Fratini, A.V., Kopka, M.L., Drew, H.R. and Dickerson, R.E. (1982) J. Biol. Chem., 257, 14686-14707.
22. Teng, M.-K., Usman, N., Frederick, C.A. and Wang, A.H.-J. (1988) Nucleic Acids Res., 16, 2671-2690.
23. Quintana, J.R., Lipanov, A.A. and Dickerson, R.E. (1991) Biochemistry, 30, 10294-10306.
24. Berman, H.M., Olson, W.K., Beveridge, D.L., Westbrook, J., Gelbin, A., Demeny, T., Hsieh, S.-H., Srinivasan, A.R. and Schneider, B. (1992) Biophys. J., 63, 751-759.
25. Packer, J.E., House, D.B. and Rasburn, E.J. (1971) J. Chem. Soc., B, 1574-1578.
26. Embrey, K.J., Searle, M.S. and Craik, D.J. (1993) Eur. J. Biochem., 211, 437.
27. Siemens (1994) SHELXTL (XP). Siemens Analytical Instruments Inc., Madison, WI.
28. Lavery, R. and Sklenar, H. (1996) CURVES version 5.0. Institut de Biologie Physico-Chimique, Paris, France.
29. BioGraphics (1997) TURBO-FRODO. AFMB-CNRS, Marseille, France.