Isolation and investigation of recombinant Salmonella typhimurium SL7207 strains producing HBcAg and HBcAg-HBs

Voprosy Virusologii

Volumn 45, Issue 2, 2000, Pages 10-14

  Karpenko, L I ^a   Ignatyev, G M ^a   Kozhina, Ye M ^a   Kashentseva, Ye A ^a   Poryvaeva, V A ^a   Melamed, N V ^a   Baiborodin, S I ^a   Smirnova, O Yu ^a   Ilyichev, A A ^a  

^a NONE

Author keywords

Attenuated Salmonella; HBcAg; HBsAg; Hepatitis B vaccine

Indexed keywords

EPITOPE; HEPATITIS B CORE ANTIGEN; HEPATITIS B SURFACE ANTIGEN;

ANIMAL; ARTICLE; BAGG ALBINO MOUSE; BIOSYNTHESIS; CELLULAR IMMUNITY; ELECTRON MICROSCOPY; GENETIC RECOMBINATION; GENETICS; IMMUNOLOGY; MOUSE; SALMONELLA TYPHIMURIUM;

ANIMALS; EPITOPES; HEPATITIS B CORE ANTIGENS; HEPATITIS B SURFACE ANTIGENS; IMMUNITY, CELLULAR; MICE; MICE, INBRED BALB C; MICROSCOPY, ELECTRON; RECOMBINATION, GENETIC; SALMONELLA TYPHIMURIUM;

EID: 0034151785     PISSN: 05074088     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Clarke B. E., Brown A. L., Grace K. G. et al. Presentation and immunogenicity of viral epitopes on the surface of hybrid hepatitis B core particles produced in bacteria // J. gen. Virol. - 1990. - Vol. 71. - P. 1109-1117.
2. Dower W. J., Miller J., Ragsdale C. W. High efficiency transformation of E. coli by high voltage electroporation // Nucl. Acids Res. - 1988. - Vol. 16. - P. 6127.
3. Hayat M. A. Principles and Techniques of Electron Microscopy. - London, 1981.
4. Hopkins S., Kraehenbuhl J. P., Schodel F. et al. A recombinant Salmonella typhimurium vaccine induces local immunity by four different routes of immunization // Infect, and Immun. - 1995. - Vol. 63. - P. 3279-3286.
5. Iwarson S. E., Tabor E., Thomas H. C. et al. Protection against hepatitis B virus infection by immunization with hepatitis c-antigen // Gastroenterology. -1985. - Vol.88. - P. 763.
6. Laemmli E. Cleavage of structural proteins during the assembly of the head of bacteriophage T4 // Nature. - 1970. - Vol. 227. - P. 680-685.
7. Milich D. R., McLachlan A. The nucleocapsid of the hepatitis B virus is both a T cell-independent and a T cell-dependent antigen // Science. - 1986. - Vol. 234. - P. 1398-1401.
8. Nardelli-Haefliger D., Kraehenbuhl J. P., Curtiss R. et al. Oral and rectal immunization of adult female volunteers with a recombinant attenuated Salmonella typhi vaccine strain // Infect. and Immun. - 1996. - Vol. 64. - P. 5219-5224.
9. Pumpen P., Borisova G. P., Crowzer R. A., Grens E. Hepatitis B virus core particles as epitope carriers // Intervirology. - 1995. - Vol. 38. - P. 63-74.
10. Roos S., Fuchs K., Roggendorf M. Protection of woodchucks from infection with woodchuck hepatitis virus by immunization with recombinant core protein // J. gen. Virol. - 1989. - Vol. 70. - P. 2087-2095.
11. Schodel F., Milich D. R., Will H. Hepatitis B virus nucleocapsid/ pre-S2 fusion protein expressed in attenuated Salmonella for oral vaccination // J. Immunol. - 1990. - Vol. 145, N 12. - P. 4317-4321.
12. Schodel F., Moriarty A. M., Peterson D. L. et al. The position of heterologous epitopes inserted in hepatitis B virus core particles determines their immunogenecity // J. Virol. - 1992. - Vol. 66. - P. 106-114.
13. Wu S., Pascual D. W., Lewis G. K., Hone D. M. Induction of mucosal and systemic responses against human immunodeficiency virus type 1 glycoprotein 120 in mice after oral immunization with a single dose of a Salmonella-HIV vector//AIDS Res. Hum. Retroviruses. - 1997. - Vol. 20. - P. 1187-1194.