Higher Incidence of Elevated Body Temperature or Increased C-Reactive Protein Level in Asthmatic Children Showing Transient Reduction of Theophylline Metabolism

Journal of Clinical Pharmacology

Volumn 40, Issue 3, 2000, Pages 284-289

  Yamaguchi, Akiko ^a   Tateishi, Tomonori ^a   Okano, Yu Ji ^a   Matuda, Takeshi ^a   Akimoto, Yasuko ^a   Miyoshi, Tomoko ^a   Kobayashi, Shinichi ^a   Koitabashi, Yasushi ^a  

^a ST MARIANNA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BRONCHODILATING AGENT; C REACTIVE PROTEIN; THEOPHYLLINE;

ADOLESCENT; ARTICLE; ASTHMA; BLOOD; CHEMICALLY INDUCED DISORDER; CHILD; CLINICAL TRIAL; FEMALE; FEVER; HUMAN; INFANT; INTRAVENOUS DRUG ADMINISTRATION; MALE; METABOLISM; PRESCHOOL CHILD; URINE;

ADOLESCENT; ASTHMA; BRONCHODILATOR AGENTS; C-REACTIVE PROTEIN; CHILD; CHILD, PRESCHOOL; FEMALE; FEVER; HUMANS; INFANT; INFUSIONS, INTRAVENOUS; MALE; THEOPHYLLINE;

EID: 0034146450     PISSN: 00912700     EISSN: None     Source Type: Journal    
DOI: 10.1177/00912700022008955     Document Type: Article

References (24)

1. Weinberger M, Hendeles L: Theophylline in asthma. N Engl J Med 1996;334:1380-1388.
2. Serafin WE: Drugs used in the treatment of asthma, in: Hardman JG, Limbird LE (eds.), Goodman & Gilman's The Pharmacological Basis of Therapeutics. 9th ed. New York: McGraw-Hill, 1996;659-682.
3. Miller M, Opheim KE, Raisys VA, Motulsky AG: Theophylline metabolism: variation and genetics. Clin Pharmacol Ther 1984;35:170-182.
4. Jenne JW, Nagasawa HT, Thompson RD: Relationship of urinary metabolites of theophylline to serum theophylline levels. Clin Pharmacol Ther 1976;19:375-381.
5. Birkett DJ, Miners JO, Attwood J: Secondary metabolism of theophylline biotransformation products in man-route of formation of 1-methyluric acid. Br J Clin Pharmacol 1983;15:117-119.
6. Sarkar MA, Hunt C, Guzelian PS, Karnes HT: Characterization of human liver cytochromes P-450 involved in theophylline metabolism. Drug Metab Dispos 1994;20:31-37.
7. Zhang Z-Y, Kaminsky LS: Characterization of human cytochromes P450 involved in theophylline 8-hydroxylation. Biochem Pharmacol 1995;50:205-211.
8. Guengerich FP: Human cytochrome P450 enzymes, in: Oritiz de Montellano PR (ed.), Cytochrome P450. New York: Plenum, 1995; 473-535.
9. Tateishi T, Asoh M, Yamaguchi A, Yoda T, Okano Y, Koitabashi Y, Kobayashi S: Developmental changes in urinary elimination of theophylline and its metabolites in pediatric patients. Pediatr Res 1999; 45:66-70.
10. Rowland M, Tozer TN: Constant-rate regimens, in: Rowland M, Tozer TN (eds.), Clinical Pharmacokinetics: Concepts and Applications. 2nd ed. Philadelphia, PA: Lea & Febiger, 1989;63-77.
11. Kubo M, Odajima Y, Ishizaki T, Kanagawa S, Yamaguchi M, Nagai T: Intraindividual changes in theophylline clearance during constant aminophylline infusion in children with acute asthma. J Pediatr 1986;108:1011-1015.
12. Boobis AR, Burley D, Davies DM, Davies DS, Harrison PI, Orme ML'E, Park BK, Goldberg LI: Theophylline, in: Dollery CT (ed.), Therapeutic Drugs. New York: Churchill Livingstone, 1991;T32-T41.
13. Warner BA, Reardon DM: A field evaluation of the Coulter STKS. Am J Clin Pathol 1992;95:207-217.
14. Kohno H: High sensitive latex photometric immunoassay in clinical chemistry, in: Miyai K, Kanno T, Ishikawa E (eds.), Progress in Clinical Biochemistry. Amsterdam: Elsevier, 1992;225-229.
15. Chang KC, Bell TD, Lauer BA, Chai H: Altered theophylline pharmacokinetics during acute respiratory viral illness. Lancet 1978;1: 1132-1133.
16. Liu TY, Minetti CA, Fortes-Dias CL, Liu T, Lin L, Lin Y: C-reactive proteins, limunectin, lipopolysaccharide-binding protein, and coagulin: molecules with lectin and agglutinin activities from Limulus polyphemus. Ann NY Acad Sci 1994;712:146-154.
17. Henrich PC, Castell JV, Andus T: Interleukin-6 and the acute phxase response. Biochem J 1990;265:621-636.
18. Akira A, Hirano T, Taga T, Kishimoto T: Biology of multifunctional cytokines: IL 6 and related molecules (IL 1 and TNF). FASEB J 1990;4:2860-2867.
19. Kraemer MJ, Furukawa CT, Koup JR, Shapiro GG, Pierson WE, Bierman CW: Altered theophylline clearance during an influenza B outbreak. Pediatr 1982;69:476-480.
20. Shedlofsky SI, Isreal BC, McClain CJ, Hill DB, Blouin RA: Endotoxin administration to humans inhibits hepatic cytochrome P450-mediated drug metabolism. J Clin Invest 1994;94:2209-2214.
21. Gorodischer R, Krasner J, McDevitt JJ, Nolan JP, Yaffee SJ: Hepatic microsomal drug metabolism after administration of endotoxin in rats. Biochem Pharmacol 1976;25:351-355.
22. Morgaan ET: Suppression of constitutive cytochrome P450 gene expression in liver of rats undergoing an acute phase response to endotoxin. Mol Pharmacol 1989;36:699-707.
23. Wright K, Morgan ET: Regulation of cytochrome P450IIC12 expression by interleukin-1α, interleukin-6, and dexamethasone. Mol Pharmacol 1991;39:468-474.
24. Abdel-Razzak Z, Loyer P, Fautrel A, Gautier J-C, Corcos L, Turlin B, Beaune P, Guillouzo A: Cytokines down-regulate expression of major cytochrome P-450 enzymes in adult human hepatocytes in primary culture. Mol Pharmacol 1993;44:707-715.