Three-Dimensional 13C-Spectroscopic Imaging in the Isolated Infarcted Rat Heart

Journal of Magnetic Resonance

Volumn 143, Issue 1, 2000, Pages 17-23

  Weidensteiner, Claudia ^a   Lanz, Titus ^a   Horn, Michael ^a   Neubauer, Stefan ^a   Haase, Axel ^a   Von Kienlin, Markus ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

Acquisition weighting; Carbon 13; Chemical shift imaging; Isolated rat heart; Myocardial infarction

Indexed keywords

CARBON; GLUTAMIC ACID;

ANIMAL; ARTICLE; HEART INFARCTION; HEART MUSCLE; IMAGE PROCESSING; IN VITRO STUDY; MALE; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PATHOLOGY; RAT; WISTAR RAT;

ANIMALS; CARBON ISOTOPES; GLUTAMIC ACID; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MYOCARDIAL INFARCTION; MYOCARDIUM; RATS; RATS, WISTAR;

EID: 0034146352     PISSN: 10907807     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmre.1999.1984     Document Type: Article

References (26)

1. 13C NMR spectroscopy, FEBS Lett. 212, 58-62 (1987).
2. 13C NMR spectroscopy, J. Biol. Chem. 263, 6964-6971 (1988).
3. R. G. Weiss, S. T. Gloth, R. Kalil-Filho, V. P. Chacko, M. D. Stern, and G. Gerstenblith, Indexing tricarboxylic acid cycle flux in intact hearts by carbon-13 nuclear magnetic resonance, Circ. Res. 70, 392-408 (1992).
4. 13C NMR spectra: Metabolic flux, regulation, and compartimentation in hearts, Biophys. J. 69, 2090-2102 (1995).
5. X. Yu, L. T. White, N. M. Alpert, E. D. Lewandowski, Subcellular metabolite transport and carbon isotope kinetics in the intramyocardial glutamate pool, Biochemistry 35, 6963-6968 (1996).
6. 13C} homonuclear decoupling, Magn. Reson. Med. 31, 374-379 (1994).
7. P. A. Bottomley, C. J. Hardy, P. B. Roemer, O. M. Mueller, Proton-decoupled, Overhauser-enhanced, spatially localized carbon-13 spectroscopy in humans, Magn. Reson. Med. 12, 348-363 (1989).
8. 13C-nuclear magnetic resonance analysis of the in vivo myocardium, Invest. Radiol. 31(10), 611-618 (1996).
9. T. R. Brown, B. M. Kincaid, K. Ugurbil, NMR chemical shift imaging in three dimensions, Proc. Natl. Acad. Sci. USA 79, 3523-3526 (1982).
10. A. A. Maudsley, S. K. Hilal, W. H. Perman, H. E. Simon, Spatially resolved high-resolution spectroscopy by "four-dimensional" NMR, J. Magn. Reson. 51, 147-152 (1983).
11. T. H. Mareci, H. R. Brooker, High-resolution magnetic resonance spectra from a sensitive region defined with pulsed field gradients, J. Magn. Reson. 57(1), 157-246 (1984).
12. T. H. Mareci, H. R. Brooker, Essential considerations for spectral localization using indirect gradient encoding of spatial information, J. Magn. Reson. 92, 229-246 (1991).
13. 1H-four-ring birdcage resonator, in "Proc., ESMRMB, 14th Annual Meeting, Bruxelles 1997," p. 93.
14. 1H-four-ring birdcage resonator, MAGMA 5, 243-246 (1997).
15. M. A. Pfeffer, J. M. Pfeffer, M. C. Fischbein, P. J. Fletcher, J. Spadaro, R. A. Kloner, E. Braunwald, Myocardial infarct size and ventricular function in rats, Circ. Res. 44, 503-512 (1979).
16. P. Gaudron, M. Blumrich, G. Ertl, Aggravation of left ventricular dilatation and reduction of survival by a calcium channel blocker in rats with chronic myocardial infarction, Am. Heart J. 125, 1226-1233 (1993).
17. 31P magnetic resonance spectroscopic imaging of regional high-energy phosphate metabolism in injured rat heart, Magn. Reson. Med. 39, 731-741 (1998).
18. 1H-decoupling, J. Magn. Reson. B 103, 103-114 (1994).
19. C.-N. Chen, D. I. Hoult, V. J. Sank, Quadrature detection coils - A further √2 improvement in sensitivity, J. Magn. Reson. 54, 324-327 (1983).
20. A. Haase, J. Frahm, D. Matthei, W. Hanicke, K. D. Merboldt, FLASH-imaging: Rapid NMR imaging using low flip angle pulses, J. Magn. Reson. 67, 258-266 (1986).
21. S. D. Wolff, R. S. Balaban, Magnetization transfer contrast (MTC) and tissue water proton relaxation in vivo, Magn. Reson. Med. 10, 135-144 (1989).
22. A. D. Sherry, B. Sumegi, B. Miller, G. L. Cottam, S. Gavva, J. G. Jones, C. R. Malloy, Orientation-conserved transfer of symmetric Krebs cycle intermediates in mammalian tissue, Biochemistry 33, 6268-6275 (1994).
23. A. J. Shaka, J. Keeler, R. Freeman, Evaluation of a new broad-band decoupling sequence: WALTZ-16, J. Magn. Reson. 53, 313-340 (1983).
24. P. A. Bottomley, R. W. Redington, W. A. Edelstein, J. F. Schenk, Estimating radiofrequency power deposition in body NMR imaging, Magn. Reson. Med. 2, 336-349 (1985).
25. Food and Drug Administration, Magnetic resonance diagnostic device, Panel recommendation and report on petitions for MR reclassification, Fed. Reg. 53, 7575-7579 (1988).
26. 13C-Spectroscopic imaging in the isolated rat heart at 11.75 T, in "Proc., ISMRM, 6th Annual Meeting, Sydney, 1998," p. 359.