Lyophilized platelets: Continued development

Transfusion Science

Volumn 22, Issue 1-2, 2000, Pages 99-105

  Bode, Arthur P ^a   Read, Marjorie S ^b  

^a EAST CAROLINA UNIVERSITY   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Adhesion; Blood platelets; Hemostasis; Lyophilization; Surface glycoproteins; Transfusion

Indexed keywords

FIBRINOGEN RECEPTOR; PARAFORMALDEHYDE; THROMBOCYTE CONCENTRATE; VON WILLEBRAND FACTOR;

ANIMAL MODEL; BLEEDING TIME; BLOOD STORAGE; CELL ADHESION; CELL STRUCTURE; CELL SURFACE; CELL VIABILITY; CONFERENCE PAPER; FREEZE DRYING; HUMAN; IMMUNE RESPONSE; IMMUNOCYTOCHEMISTRY; NONHUMAN; RABBIT; REHYDRATION; THROMBOCYTE AGGREGATION; THROMBOCYTE FUNCTION; THROMBOCYTOPENIA;

ANIMALS; BLOOD PLATELETS; BLOOD PRESERVATION; CELL ADHESION; DOGS; FIBRINOGEN; FREEZE DRYING; HEMOSTASIS; HUMANS; PLATELET GLYCOPROTEIN GPIB-IX COMPLEX; PLATELET TRANSFUSION; VON WILLEBRAND FACTOR;

EID: 0034144299     PISSN: 09553886     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0955-3886(00)00028-X     Document Type: Conference Paper

References (14)

1. Brinkhous KM, Read MS. Preservation of platelet receptors for platelet aggregating factor/von Willebrand factor by air drying, freezing, or lyophilization: new stable preparations for von Willebrand factor assays. Thromb Res 1978;13:591-7.
2. Chao FC, Kim BK, Houranieh AM, Liang FH, Konrad MW, Swisher SN, Tullis JL. Infusible platelet membrane microvesicles: a potential transfusion substitute for platelets. Transfusion 1996;36:536-42.
3. Levi M, Friederich PH, Middleton S, Harris R, Biemond BJ, Levin J, tenCate JW. Correction of the bleeding time by the infusion of fibrinogen-coated albumin microcapsules in severely thrombocytopenic rabbits. Blood 1997;90(Suppl 1):261a.
4. Yen RKC, Ho TWC, Blajchman MA. A new hemostatic agent: thrombospheres shorten the bleeding time (BT) in thrombocytopenic rabbits. Thromb Haemost 1995;73: 986.
5. Bode AP, Read MS, Summaria L, Lust RM. Lyophilized platelets; nearing clinical trials. Platelets 1997;8:436-7.
6. Bode AP, Read MS, Reddick RL. Activation and adherence of lyophilized human platelets on canine vessel strips in the Baumgartner perfusion chamber. J Lab Clin Med 1999;133:200-11.
7. Read MS, Reddick RL, Bode AP, Bellinger DA, Nichols TC, Taylor KK, Smith SV, McMahon DK, Griggs TR, Brinkhous KM. Preservation of hemostatic and structural properties of rehydrated lyophilized platelets: potential for long-term storage of dried platelets for transfusion. Proc Natl Acad Sci USA 1995;92:397-401.
8. Bode AP, Knupp CL, Miller DT. Effect of activation inhibitors on the loss of Glycoprotein Ib during storage of platelet concentrates. J Lab Clin Med 1990;115:669-79.
9. Khandelwal G, Sanders Jr WE, Bode AP, Nichols TC, Erickson G, Read MS. von Willebrand factor binding to rehydrated lyophilized platelet surface GpIb and inhibition by monoclonal antibody to GpIb. Fed Am Soc Exp Biol J 1997;11:A1812.
10. Sanders WE Jr, Khandelwal G, Bellinger DA, Bode AP, Read MS. Fibrinogen binding to rehydrated lyophilized platelet surface GpIIbIIIa: normal clot formation and TPA lysis. Blood 1996;88(Suppl 1):30a.
11. Read MS, Khandelwal G, Miller RS, Taylor KK, Bode AP, Nichols TC, Reddick RL, Griggs TR. Rehydrated lyophilized platelets: a proposed mechanism contributing to the hemostatic action. Blood 1995;86(Suppl 1):907a.
12. Görög P, Ahmed A. Haemostatometer: a new in vitro technique for assessing haemostatic activity of blood. Thromb Res 1984;34:341-57.
13. Blajchman MA, Lee DH. The thrombocytopenic rabbit bleeding time model to evaluate the in vivo hemostatic efficacy of platelets and platelet substitutes. Transfus Med Rev 1997;11:95-105.
14. Bode AP, Blajchman MA, Bardossy L, Read MS. Hemostatic properties of human lyophilized platelets in a thrombocytopenic rabbit model and a simulated bleeding time device. Blood 1994;84(Suppl 1):464a.