Oligodendrocytes as glucocorticoids target cells: Functional analysis of the glycerol phosphate dehydrogenase gene

Journal of Neuroscience Research

Volumn 59, Issue 3, 2000, Pages 436-445

  Cheng, Janet D ^a   De Vellis, Jean ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b 68 177 NPI   (United States)

Author keywords

C6 glioma; CAMP; Glia; Glucocorticoid response elements; Glucocorticoids; Glycerol 3 phosphate dehydrogenase; Oligodendrocytes; Phorbol esters

Indexed keywords

CYCLIC AMP; GLUCOCORTICOID; GLYCEROL 3 PHOSPHATE DEHYDROGENASE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DNA FLANKING REGION; DNA RESPONSIVE ELEMENT; DNA SEQUENCE; ENHANCER REGION; GENE EXPRESSION REGULATION; GLIA CELL; GLIOMA; NERVE CELL DIFFERENTIATION; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; RAT; SECOND MESSENGER;

ANIMALS; BASE SEQUENCE; CYCLIC AMP; ENHANCER ELEMENTS (GENETICS); EXONS; GLUCOCORTICOIDS; GLYCEROL-3-PHOSPHATE DEHYDROGENASE (NAD+); GLYCEROLPHOSPHATE DEHYDROGENASE; MICE; MOLECULAR SEQUENCE DATA; OLIGODENDROGLIA; RATS; TETRADECANOYLPHORBOL ACETATE; TUMOR CELLS, CULTURED;

EID: 0034142349     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4547(20000201)59:3<436::AID-JNR19>3.0.CO;2-Z     Document Type: Article

References (58)

1. Auphan N, DiDonato JA, Rosette C, Helmberg A, Karin M. 1995. Immunosuppression by glucocorticoids: inhibition of NF-κB activity through induction of IκB synthesis. Science 270:286-290.
2. Barres BA, Lazar MA, Raff MC. 1994. A novel role for thyroid hormone, glucocorticoids and retinoic acid in timing oligodendrocyte development. Development 120:1097-1106.
3. Bennett K, McGinnis J, de Vellis J. 1977. Reversible inhibition norepinephrine induction of lactate dehydrogenase by cytochalasin B in rat glial C6 cells. J Cell Phys 93:247-260.
4. Breen G, de Vellis J. 1974. Regulation of glycerol phosphate dehydrogenase by hydrocortisone in dissociated rat cerebral cell culture. Dev Biol 41: 255-266.
5. 2-dibutyryl cyclic AMP, norepinephrine and isobutyl methyl-xanthine in rat brain cell cultures. J Biol Chem 253:2554-2562.
6. Bressler JP. 1987. Increased diacylglycerol levels inhibit [20-tritium] phorbol 12, 12-dibutyrate binding and the glucocorticoid-mediated increase in glycerol phosphate dehydrogenase levels in C6 rat glioma cells. J Neurochem 48:181-186.
7. Byravan S, Canipagnoni AT. 1994. Serum factors and hydrocortisone influence the synthesis of myelin basic proteins in mouse brain primary cultures. Int J Dev Neurosci 12:343-351.
8. Chan JR, Phillips LJ, Glaser M. 1998. Glucocorticoids and progestins signal the initiation and enhance the rate of myelin formation. Proc Natl Acad Sci 95:10459-10464.
9. Cheng JD, Zhao P, Espinosa de los Monteros A, de Vellis J. 1997. Glial-and fat-specific expression of the rat glycerol phosphate dehydrogenase-luciferase fusion gene in transgenic mice. J Neurosci Res 50:300-311.
10. Damm K, Thompson CC, Evans RM. 1989. Protein encoded by v-erbA functions as a thyroid-hormone receptor antagonist. Nature 339:593-597.
11. de Vellis J, Inglish D. 1968. Hormonal control of glycerol-phosphate dehydrogenase in the rat brain. J Neurochem 15:1061-1070.
12. de Vellis J, Inglish, D. 1973. Age-dependent changes in the regulation of glycerol-phosphate dehydrogenase in the rat brain and in a glial cell line. Prog Brain Res 40:321-330.
13. DeFranco DB, Qi M, Borror KC, Garabedian MJ, Brautigan DL. 1991. Protein phosphatase types 1 or 2A regulate nucleocytoplasmic shuttling of glucocorticoid receptors. Mol Endocrinol 5:1215-1228.
14. Denner LA, Weigel NL, Maxwell BL, Schrader WT, O'Malley BW. 1990. Regulation f progesterone receptor-mediated transcription by phosphorylation. Science 250:1740-1743.
15. Diamond ML, Miner JN, Yoshinaga SK, Yamamoto KR. 1990. Transcription factor interactions selectors of positive or negative regulation from a single DNA. Science 249:1266-1272.
16. Dobson DE, Groves DL, Spiegelman BM. 1987. Nucleotide sequence and hormonal regulation of mouse glycerophosphate dehydrogenase mRNA during adipocyte and muscle cell differentiation. J Biol Chem 262:1804-1809.
17. Finch CE, Master JN, Nichols NR. 1990. Molecular mechanisms in the neurobiology of stress: analysis of corticosterone-responsive mRNA from rat hippocampus. In: Nappi G, Martignoni E, Gennazzani AR and Petraglia F, editors. Stress and the aging brain. New York: Raven Press. p77-81.
18. Fisher M, Gapp D, Kozak L. 1981. Immunohistochemical localization of sn-glycerol-3-phosphate dehydrogenase in Bergmann glia and oligodendroglia in the mouse cerebellum. Dev Brain Res 1:341-154.
19. Gordon MN, Kumar S, Espinosa de los Monteros A, de Vellis J. 1992. Ontogeny of glycerol phosphate dehydrogenase-positive oligodendrocytes in rat brain: impaired differentiation of oligodendrocytes in the myelin deficient mutant rat. Intern J Dev Neurosci 4:243-253.
20. Gwynn B, Lyford K, Birkenmeier EH. 1990. Sequence conservation and structural organization of the glycerol-3-phosphate dehydrogenase promoter in mice and humans. Mol Cell Biol 10:5244-5256.
21. Ireland RC, Kotarski MA, Johnston LA, Stadler U, Birkenmeier E, Kozak LP. 1986. Primary structure of the mouse glycerol-3-phosphate dehydrogenase gene. J Biol Chem 261:11779-11785.
22. Johnston LA, Kotarski MA, Jerry DJ, Kozak LP. 1989. An ubiquitously expressed gene 3.5 kilobases upstream of the glycerol-3-phosphate dehydrogenase gene in mice. Mol Cell Biol 9:935-945.
23. Kozak LP, Kozak U, Jerry J, Wells J. 1990. Obesity: toward a molecular approach. Bray GA, Ricquier D and Spiegelman BM, editors. New York: Wiley-Liss. p 263-272.
24. Kumar S, Cole R, Chiappelli F, de Vellis J. 1989. Differential regulation of oligodendrocyte markers by glucocorticoids: post-transcriptional regulation of both proteolipid protein and myelin basic protein and transcriptional regulation of glycerol phosphate dehydrogenase. Proc Natl Acad Sci 86:6807-6811.
25. Kumar S, de Vellis J. 1988. Glucocorticoid mediated functions in glial cells. In: Kimelberg HK, editor. Glial cell receptors. New York: Raven Press. p. 243-263.
26. Kumar S, Holmes E, Scully S, Biren BW, Wilson RH, de Vellis J. 1986. The hormonal regulation of gene expression of glial markers: glutamine synthetase and glycerol phosphate dehydrogenase in primary cultures of rat brain and in C6 cell line. J Neurosci Res 16:251-264.
27. Kumar S, Sachar K, Huber J, Weingarten DP, de Vellis J. 1985. Glucocorticoids regulate the transcription of glycerol phosphate dehydrogenase in cultured glial cells. J Biol Chem 260:14743-14747.
28. Kumar S, Weingarten DP, Callahan JW, Sachar K, de Vellis J. 1984. Regulation of mRNAs for three enzymes in the glial cell model, C6 cell line. J Neurochem 43:1455-1463.
29. Leveille PJ, McGinnis JF, Maxwell DF, de Vellis J. 1980. Immunocytochemical localization of glycerol-3-phosphate dehydrogenase in rat oligodendrocytes. Brain Res 196:287-305.
30. Lopez-Cardozo M, Sykes JEC, Van der Pal RHM, Van Golde LMG. 1989. Development of oligodendrocytes. Studies of rat glial cells cultured in chemically-defined medium. J Dev Physiol 12:117-127.
31. Mader S, White J. 1993. A steroid-inducible promoter for the controlled overexpression of cloned genes in eukaryotic cells. Proc Natl Acad Sci USA 90:5603-5607.
32. Maizel JV Jr, Lenk RP. 1981. Enhanced graphic matrix analysis of nucleic acid and protein sequences. Proc Natl Acad Sci USA 78:7665-7669.
33. Masters JN, Finch CE, Nichols NR. 1994. Rapid increase in glycerol phosphate dehydrogenase mRNA in adult rat brain: a glucocorticoid-dependent stress response. Neuroendocrinology 60:23-35.
34. McCarthy KD, de Vellis J. 1980. Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue. J Cell Biol 85:8790-8902.
35. McEwen BS, de Kloet ER, Rostene WH. 1986. Adrenal steroid receptors and actions in the nervous system. Physiol Rev 66:1121-1150.
36. McEwen BS. 1999. Stress and the aging hippocampus. Front Neuroendocrinol 20:49-70.
37. McGinnis J, de Vellis J. 1978. Glucocorticoid regulation in rat brain cell cultures: hydrocortisone increases the rate of synthesis of glycerol phosphate dehydrogenase in C6 glioma cells. J Biol Chein 253:8483-8492.
38. McGinnis J, de Vellis J. 1981. Cell surface modulation of gene expression in brain cells by down regulation of glucocorticoid receptors. Proc Natl Acad Sci USA 78:1288-1292.
39. McGinnis J, de Vellis J. 1977. Differential hormonal regulation of L-glycerol 3-phosphate dehydrogenase in rat brain and skeletal muscle. Arch Biochem Biophys 179:682-689.
40. Meyer JS, Leveille PJ, de Vellis J, Gerlach JL, McEwen BS. 1982. Evidence for glucocorticoid target cells in the rat optic nerve. Hormone binding and glycerol phosphate dehydrogenase induction. J Neurochem 39:423-434.
41. Montiel F, Aranda A, Villa A, Pascual A. 1986. Regulation of glycerol phosphate dehydrogenase and lactate dehydrogenase activity by forskolin and dibutyryl cyclic AMP in the C6 glial cells. J Neurochem 47:1336-1343.
42. Montz HP, Althaus HH, Gebicke-Haerter PJ, Neuhoff V. 1985. Glycerol phosphate dehydrogenase activity of oligodendrocytes isolated from adult pig brain: its inducibility by hydrocortisone. J Neurochem 45:1201-1204.
43. Needleman SB, Wunsch CD. 1970. A general method applicable to the search for similarities in the amino acid sequence of two proteins. J Mol Biol 48:443-453.
44. r protein, glycerol phosphate dehydrogenase. J Neuroendocrinol 8:867-876.
45. Nichols NR, Masters JN, Finch CE. 1990. Changes in gene expression in hippocampus in response to glucocorticoids and stress. Brain Res Bull 24:658-662.
46. O'Malley BW. 1990. The steroid receptor superfamily: more excitement predicted for the future. Mol Endocrinol 4:363-370.
47. Okayama H, Berg P. 1983. A cDNA cloning vector that permits expression of cDNA inserts in mammalian cells. Mol Cell Biol 3:280-289.
48. Preston SL, McMorris FA. 1984. Adrenalectomy of rats results in hypomyelination of the central nervous system. J Neurochem 42:262-267.
49. Ray A, Prefontaine KE. 1994. Physical association and functional antagonism between the p65 subunit of transcription factor NF-κB and the glucocorticoid receptor. Proc Natl Acad Sci USA 91:752-756.
50. Sanger F, Nicklen S, Coulson AR. 1977. DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci USA 74:5463-5467.
51. Scheinman RI, Gualberto A, Jewell CM, Cidlowski JA, Baldwin AS Jr. 1995a. Characterization of mechanisms involved in transrepression of NF-κB by activated glucocorticoid receptors. Mol Cell Biol 15:943-953.
52. Scheinman RI, Cogswell PC, Lofquist AK, Baldwin AS Jr. 1995b. Role of transcriptional activation of IκB alpha in mediation of immunosuppression by glucocorticoids. Science 270:283-286.
53. Schule R, Evans RM. 1991. Retinoic acid is a negative regulator of AP-1-responsive genes. Proc Natl Acad Sci USA 88:6092-6096.
54. Thurston JH, Hauhart RE, Dirgo JA, Jones EM. 1978. Mechanisms of increased brain glucose and glycogen after hydrocortisone: possible clinical significance. Ann Neurol 7:515-523.
55. Verdi JM, Kampf K, Campagnoni AT. 1989. Translational regulation of myelin protein synthesis by steroids. J Neurochem 52:321-324.
56. Vielkind U, Walencewica A, Levein JM, Bohn MC. 1990. Type II glucocorticoid receptors are expressed in oligodendrocytes and astrocytes. J Neurosci Res 27:360-373.
57. Warringa RA, Hoeben RC, Koper JW, Sykes JE, van Golde LM, Lopes-Cardozo M. 1987. Hydrocortisone stimulates the development of oligodendrocytes in primary glial cultures and affects glucose metabolism and lipid synthesis in these cultures. Brain Res 431:79-86.
58. Yang-Yen HF, Chambard JC, Sun YL, Smeal T, Schmidt TJ, Drouin J, Karin M. 1990. Transcriptional interference between c-jun and the glucocorticoid receptor: mutual inhibition of DNA binding due to direct protein-protein interaction. Cell 62:1205-1215.