Ventilatory and central neurochemical reorganisation of O2 chemoreflex after carotid sinus nerve transection in rat

Journal of Physiology

Volumn 522, Issue 3, 2000, Pages 493-501

  Roux, J C ^a,b   Peyronnet, J ^a   Pascual, O ^a   Dalmaz, Y ^a   Pequignot, J M ^a  

^a UNIVERSITÉ LYON 1   (France)

^b UMR 5578 CNRS Univ   (France)

Author keywords

[No Author keywords available]

Indexed keywords

OXYGEN; TYROSINE 3 MONOOXYGENASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREATHING PATTERN; BREATHING RATE; CAROTID SINUS NERVE; CATECHOLAMINE NERVE CELL; CHEMORECEPTOR REFLEX; CONTROLLED STUDY; ENZYME ACTIVITY; HYPOXIA; NERVE TRANSECTION; NEUROCHEMISTRY; NONHUMAN; PRIORITY JOURNAL; RAT; TIDAL VOLUME; ANIMAL TISSUE; BREATHING REFLEX; DENERVATION; IN VIVO STUDY; SHAM PROCEDURE; WAKEFULNESS;

EID: 0034142257     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1469-7793.2000.t01-4-00493.x     Document Type: Article

References (48)

1. BARTLETT, D. JR & TENNEY, S. M. (1970). Control of breathing in experimental anemia. Respiration Physiology 10, 384-395.
2. BARTOLI, A., CROSS, B. A., GUZ, A., HUSZCZUK, A. & JEFFRIES, R. (1975). The effect of varying tidal volume on the associated phrenic motoneurone output: studies of vagal and chemical feedback. Respiration Physiology 25, 135-155.
3. BIANCHI, A. L., DENAVIT-SAUBIÉ, M. & CHAMPAGNAT, J. (1995). Central control of breathing in mammals: neuronal circuitry, membrane properties, and neurotransmitters. Physiological Reviews 75, 1-45.
4. BISGARD, G. E., FORSTER, H. V. & KLEIN, J. P. (1980). Recovery of peripheral chemoreceptor functions after denervation in ponies. Journal of Applied Physiology 49, 964-970.
5. BISGARD, G. E., FORSTER, H. V., ORR, J. A., BUSS, D. D., RAWLINGS, C. A. & RASMUSSEN, B. (1976). Hypoventilation in ponies after carotid body denervation. Journal of Applied Physiology 40, 184-190.
6. BRADLEY, G. W., VON EULER, C., MARTTILA, I. & ROOS, B. (1975). A model of the central and reflex inhibition of inspiration in the cat. Biological Cybernetics 19, 105-116.
7. BROPHY, S., FORD, T. W., CAREY, M. & JONES, J. F. (1999). Activity of aortic chemoreceptors in the anaesthetized rat. Journal of Physiology 514, 821-828.
8. CARDENAS, H. & ZAPATA, P. (1983). Ventilatory reflexes originated from carotid and extracarotid chemoreceptors in rats. American Journal of Physiology 244, R119-125.
9. CARLSSON, A., DAVIS, J. N., KEHR, W., LINDQVIST, M. & ATACK, C. V. (1972). Simultaneous measurement of tyrosine and tryptophan hydroxylase activities in brain in vivo using an inhibitor of the aromatic amino acid decarboxylase. Naunyn-Schmiedeberg's Archives of Pharmacology 275, 153-168.
10. CHAMPAGNAT, J., DENAVIT-SAUBIÉ, M., HENRY, J. L. & LEVIEL, V. (1979). Catecholaminergic depressant effects on bulbar respiratory mechanisms. Brain Research 160, 57-68.
11. CLARK, F. J. & VON EULER, C., (1972). On the regulation of depth and rate of breathing. Journal of Physiology 222, 267-295.
12. COLES, S. K. & DICK, T. E. (1996). Neurones in the ventrolateral pons are required for post-hypoxic frequency decline in rats. Journal of Physiology 497, 79-94.
13. DENAVIT-SAUBIÉ, M. & FOUTZ, A. (1997). Neuropharmacology of respiration. In Neural Control of the Respiratory Muscles, ed. MILLER, A. D., BIANCHI, A. L. & BISHOP, B. P., pp. 143-155. CRC Press, New York.
14. DICK, T. E., COLES, S. K. & JODKOWSKI, J. S. (1995). A 'pneumotaxic centre' in ventrolateral pons of rats. In Ventral Brainstem Mechanisms and Control Functions, ed. TROUTH, O., MILLIS, R., KIWELL-SCHÖNE, H. & SCHLÄFKE, M., pp. 723-737. Marcel Dekker, New York.
15. ERRCHIDI, S., MONTEAU, R. & HILAIRE, G. (1991). Noradrenergic modulation of the medullary respiratory rhythm generator in the newborn rat: an in vitro study. Journal of Physiology 443, 477-498.
16. EUGENIN, J., LARRAIN, C. & ZAPATA, P. (1990). Functional recovery of the ventilatory chemoreflexes after partial chronic denervation of the nucleus tractus solitarius. Brain Research 523, 263-272.
17. 2 chemoreflex drive of ventilation in the awake rat. Journal of Physiology 74, 411-417.
18. FINLEY, J. C. & KATZ, D. M. (1992). The central organisation of carotid body afferent projections to the brainstem of the rat. Brain Research 572, 108-116.
19. GAUTIER, H. & BONORA, M. (1992). Ventilatory and metabolic responses to cold and hypoxia in intact and carotid body-denervated rats. Journal of Applied Physiology 73, 847-854.
20. GUYENET, P. G., KOSHIYA, N., HUANGFU, D., VERBERNE, A. J. & RILEY, T. A. (1993). Central respiratory control of A5 and A6 pontine noradrenergic neurons. American Journal of Physiology 264, R1035-1044.
21. HORN, E. M. & WALDROP, T. G. (1998). Suprapontine control of respiration. Respiration Physiology 114, 201-211.
22. HOUSLEY, G. D., MARTIN-BODY, R. L., DAWSON, N. J. & SINCLAIR, J. D. (1987). Brain stem projections of the glossopharyngeal nerve and its carotid sinus branch in the rat. Neuroscience 22, 237-250.
23. KRIEGER, E. M. (1904). Neurogenic hypertension in rat. Circulation Research 15, 511-521.
24. KRIEGER, E. M. (1970). The acute phase of neurogenic hypertension in rat. Experentia Basel 26, 628-629.
25. MCDONALD, D. M. & BLEWETT, R. W. (1981). Location and size of carotid body-like organs (paraganglia) revealed in rats by the permeability of blood vessels to Evans blue dye. Journal of Neurocytology 10, 607-643.
26. MAJUMDAR, S., MILLS, E. & SMITH, P. G. (1983). Degenerative and regenerative changes in central projections of glossopharyngeal and vagal sensory neurons after peripheral axotorny in cats: a structural basis for central reorganization of arterial chemoreflex pathways Neuroscience 10, 841-849.
27. MAJUMDAR, S., SMITH, P. G. & MILLS, E. (1982). Evidence for central reorganisation of ventilatory chemoreflex pathways in the cat during regeneration of visceral afferents in the carotid sinus nerve. Neuroscience 7, 1309-1316.
28. MARTIN-BODY, R. L. (1988). Brain transections demonstrate the central origin of hypoxic ventilatory depression in carotid body-denervated rats. Journal of Physiology 407, 41-52.
29. MARTIN-BODY, R. L., ROBSON, G. J. & SINCLAIR, J. D. (1985). Respiratory effects of sectioning the carotid sinus glossopharyngeal and abdominal vagal nerves in the awake rat. Journal of Physiology 361, 35-45.
30. MARTIN-BODY, R. L., ROBSON, G. J. & SINCLAIR, J. D. (1986). Restoration of hypoxic respiratory responses in the awake rat after carotid body denervation by sinus nerve section. Journal of Physiology 380, 61-73.
31. MATSUOKA, T., DOTTA, A. & MORTOLA, J. (1994). Metabolic response to ambiant temperature and hypoxia in sinoaortic-denervated rats. American Journal of Physiology 266, R387-391.
32. MORTOLA, J. P. & SAIKI, C. (1996). Ventilatory response to hypoxia in rats: gender differences. Respiration Physiology 106, 21-34.
33. NOLAN, P. C., DILLON, G. H. & WALDROP, T. G. (1995). Central hypoxic chemoreceptors in the ventrolateral medulla and caudal hypothalamus. Advances in Experimental Medicine and Biology 393, 261-266.
34. NOLAN, P. C. & WALDROP, T. G. (1993). In vivo and in vitro responses of neurons in the ventrolateral medulla to hypoxia. Brain Research 630, 101-114.
35. NOLAN, P. C. & WALDROP, T. G. (1996). In vitro responses of VLM neurons to hypoxia after normobaric hypoxic acclimatization. Respiration Physiology 105, 23-33.
36. OLSON, E. B., VIDRUK, E. H. & DEMPSEY, J. A. (1988). Carotid body excision changes ventilatory control in awake rats. Journal of Applied Physiology 64, 666-671.
37. PALKOVITS, M. & BROWNSTEIN, M. J. (1988). Maps and Guide to Microdissection of the Rat Brain. Elsevier, Amsterdam.
38. SAPRU, H. N. & KRIEGER, A. J. (1977). Carotid and aortic chemoreceptor function in the rat. Journal of Applied Physiology 42, 344-348.
39. SCHMITT, P., SOULIER, V., PEQUIGNOT, J. M., PUJOL, J. F. & DENAVIT-SAUBIÉ, M. (1994). Ventilatory acclimatization to chronic hypoxia: relationship to noradrenaline metabolism in the rat solitary complex. Journal of Physiology 477, 331-337.
40. SMITH, D. W., BULLER, K. M. & DAY, T. A. (1995). Role of ventrolateral medulla catecholamine cells in hypothalamic neuroendocrine cell responses to systemic hypoxia. Journal of Neuroscience 12, 7979-7988.
41. SMITH, P. G. & MILLS, E. (1979). Physiological and ultrastructural observations on regenerated carotid sinus nerves after removal of the carotid bodies in cats. Neuroscience 4, 2009-2020.
42. SMITH, P. G. & MILLS, E. (1980). Restoration of reflex ventilatory response to hypoxia after removal of carotid bodies in the cat. Neuroscience 5, 573-580.
43. SOULIER, V., COTTET-EMARD, J. M., PEQUIGNOT, J., HANCHIN, F., PEYRIN, L. & PEQUIGNOT, J. M. (1992). Differential effects of long-term hypoxia on norepinephrine turnover in brain stem cell groups. Journal of Applied Physiology 73, 1810-1814.
44. SUN, M. K. & REIS, D. J. (1994). Hypoxia selectively excites vasomotor neurons of rostral ventrolateral medulla in rats. American Journal of Physiology 266, R245-256.
45. TATSUMI, K., PICKETT, C. K., JACOBY, C. R., WEIL, J. V. & MOORE, L. G. (1997). Role of endogenous female hormones in hypoxic chemosensitivity. Journal of Applied Physiology 83, 1706-1710.
46. VALENTINO, R. J., FOOTE, S. L. & PAGE, M. E. (1993). The locus coeruleus as a site for integrating corticotropin-releasing factor and noradrenergic mediation of stress responses. Annals of the New York Academy of Sciences 697, 173-188.
47. WAITES, B. A., ACKLAND, G. L., NOBLE, R. & HANSON, M. A. (1996), Red nucleus lesions abolish the biphasic respiratory response to isocapnic hypoxia in decerebrate young rabbits. Journal of Physiology 495, 217-225.
48. ZAPATA, P., STENSAAS, L. J. & EYZAGUIRRE, C. (1976). Axon regeneration following a lesion of the carotid nerve: electrophysiological and ultrastructural observations. Brain Research 113, 235-253.