Inhibition of NF-κB-DNA binding by mercuric ion: Utility of the non- thiol reductant, tris(2-carboxyethyl)phosphine hydrochloride (TCEP), on detection of impaired NF-κB-DNA binding by thiol-directed agents

Toxicology in Vitro

Volumn 14, Issue 1, 2000, Pages 7-16

  Dieguez Acuna F J ^a   Woods, J S ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Mercuric ion; N ethylmaleimide; NF B; Thiol; Tris(2 carboxyethyl)phosphine hydrochloride

Indexed keywords

DITHIOTHREITOL; DNA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MERCURY; N ETHYLMALEIMIDE; OLIGONUCLEOTIDE; PHOSPHINE DERIVATIVE; RECOMBINANT PROTEIN; REDUCING AGENT; THIOL REAGENT; TRIS(2 CARBOXYETHYL)PHOSPHINE; TRIS(2-CARBOXYETHYL)PHOSPHINE; ALKYLATING AGENT; CYSTEINE; THIOL DERIVATIVE;

ARTICLE; DRUG ANTAGONISM; DRUG EFFECT; HUMAN; METABOLISM; POLYACRYLAMIDE GEL ELECTROPHORESIS; APOPTOSIS; CELL DEATH; CHEMICAL BOND; CONSENSUS SEQUENCE; DNA BINDING; DNA TRANSCRIPTION; ELECTROPHORETIC MOBILITY; OXIDATION REDUCTION REACTION;

DITHIOTHREITOL; DNA; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ETHYLMALEIMIDE; HUMANS; MERCURY; NF-KAPPA B; OLIGONUCLEOTIDES; PHOSPHINES; RECOMBINANT PROTEINS; REDUCING AGENTS; SULFHYDRYL REAGENTS;

EID: 0034136467     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0887-2333(99)00091-0     Document Type: Article

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