Pharmacophore modelling of structurally unusual diltiazem mimics at L-type calcium channels

Journal of Computer-Aided Molecular Design

Volumn 14, Issue 5, 2000, Pages 427-433

  Schleifer, K J ^a   Tot, E ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

Benzothiazepines; Calcium entry blockers; McN 5691; Molecular modelling; Papaverine; Tetrandrine

Indexed keywords

CALCIUM; ELECTRONS; PHARMACODYNAMICS;

BENZOTHIAZEPINE; CALCIUM ENTRY BLOCKER; DILTIAZEM; L-TYPE CALCIUM CHANNELS; MCN-5691; PAPAVERINE; PHARMACOPHORE MODELS; TETRANDRINE; THEORETICAL STUDY; VERAPAMIL;

MOLECULAR OXYGEN;

ANTIOQUINE; BENZOTHIAZEPINE DERIVATIVE; BENZYLISOQUINOLINE DERIVATIVE; CALCIUM ANTAGONIST; CALCIUM CHANNEL; DICLOFURIME; DILTIAZEM; DILTIAZEM DERIVATIVE; LAUDANOSINE; N (3,4 DIMETHOXYPHENETHYL) 5 METHOXY N,ALPHA DIMETHYL 2 (PHENYLETHYNYL)PHENYLPROPANAMINE; N (3,5 DIMETHOXYPHENETHYL) 5 METHOXY 2 (PHENYLETHYNYL)AMPHETAMINE; NATURAL PRODUCT; OXIME; OXYGEN; PAPAVERINE; TETRANDRINE; VERAPAMIL DERIVATIVE;

ARTICLE; BINDING AFFINITY; CIS ISOMER; CONTROLLED STUDY; DRUG ANALYSIS; DRUG BINDING SITE; DRUG STRUCTURE; ELECTRICITY; ELECTRON; ENANTIOMER; MOLECULAR MIMICRY; PHARMACOPHORE; PRIORITY JOURNAL; THEORETICAL STUDY;

EID: 0034130176     PISSN: 0920654X     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1008188505899     Document Type: Article

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