Cross-reactivity of antiidiotypic antibodies with DNA in systemic lupus erythematosus

Arthritis and Rheumatism

Volumn 43, Issue 2, 2000, Pages 429-439

  Eivazova, Elvira R ^a   McDonnell, James M ^a   Sutton, Brian J ^a   Staines, Norman A ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIIDIOTYPIC ANTIBODY; DNA; DNA ANTIBODY; DOUBLE STRANDED DNA; IMMUNOGLOBULIN IDIOTYPE; MONOCLONAL ANTIBODY; SYNTHETIC PEPTIDE;

ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CROSS REACTION; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNIZATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SURFACE PLASMON RESONANCE; SYSTEMIC LUPUS ERYTHEMATOSUS;

ANIMALS; ANTIBODIES, ANTI-IDIOTYPIC; ANTIBODIES, ANTINUCLEAR; ANTIBODY SPECIFICITY; AUTOANTIBODIES; BINDING, COMPETITIVE; CROSS REACTIONS; DNA; IMMUNIZATION; LUPUS ERYTHEMATOSUS, SYSTEMIC; MICE; MICE, INBRED BALB C; MICE, INBRED MRL LPR; MICE, INBRED NZB; SURFACE PLASMON RESONANCE;

EID: 0034130097     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/1529-0131(200002)43:2<429::AID-ANR25>3.0.CO;2-N     Document Type: Article

References (45)

1. Hahn BH, Ebling FM. A public idiotypic determinant is present on spontaneous cationic IgG antibodies to DNA from mice of unrelated lupus-prone strains. J Immunol 1984;133:3015-9.
2. Davidson A, Preud'homme JL, Solomon A, Chang MD, Beede S, Diamond B. Idiotypic analysis of myeloma proteins; anti-DNA activity of monoclonal immunoglobulins bearing an SLE idiotype is more common in IgG than in IgM antibodies. J Immunol 1987;138:1515-8.
3. Rauch J, Murphy E, Roths JB, Stollar BD, Schwartz RS. A high frequency idiotypic marker of anti-DNA autoantibodies in MRL-lpr/lpr mice. J Immunol 1982;129:236-41.
4. Isenberg DA, Williams W, Axford J, Bakimer R, Bell D, Casasceca-Grayson T, et al. Comparison of DNA antibody idiotypes in human sera: an international collaborative study of 19 idiotypes from 11 different laboratories. J Autoimmun 1990;3: 393-414.
5. Shefner R, Manheimer-Lory A, Davidson A, Paul E, Aranow C, Katz J, et al. Idiotypes in systemic lupus erythematosus: clues for understanding etiology and pathogenesis. Chem Immunol 1990; 48:82-108.
6. Morgan A, Isenberg DA, Naparstek Y, Rauch J, Duggan D, Khiroya R, et al. Shared idiotypes are expressed on mouse and human anti-DNA autoantibodies. Immunology 1985;56:393-9.
7. Paul E, Diamond B. Characterization of two human anti-DNA antibodies bearing the pathogenic idiotype 8.12. Autoimmunity 1993;16:13-21.
8. Blank M, Krup M, Mendlovic S, Fricke H, Mozes E, Talal N, et al. The importance of the pathogenic idiotype in the induction of SLE in naive mice. Scand J Immunol 1990;31:45-52.
9. Shoenfeld Y, Mozes E. Pathogenic idiotypes of autoantibodies in autoimmunity: lessons from new experimental models of SLE. FASEB J 1990;4:2646-51.
10. Abdou NI, Wall H, Lindsley HB, Halsey JF, Suzuki T. Network theory in autoimmunity: in vitro suppression of serum anti-DNA antibody binding to DNA by anti-idiotype antibody in systemic lupus erythematosus. J Clin Invest 1981;67:1297-305.
11. Uner AH, Knupp CJ, Tatum AH, Gavalchin J. Treatment with antibody reactive with the nephritogenic idiotype, IdLNF1, suppresses its production and leads to prolonged survival of (NZB × SWR)F1 mice. J Autoimmun 1994;7:27-44.
12. Zouali M, Eyquem A. Idiotypic-anti-idiotypic interactions in systemic lupus erythematosus: demonstrations of oscillatory levels of anti-DNA autoantibodies and reciprocal anti-idiotypic activity in a single patient. Ann Immunol 1083;134C:377-83.
13. Knupp CJ, Uner AH, Tatum AH, Gavalchin J. The onset of nephritis in the (NZW × SWR)FI murine model of systemic lupus erythematosus correlates with an increase in the ratio of CD4 to CDS T lymphocytes specific for the nephritogenic idiotype (IdLNF1). Clin Immunol Immunopathol 1992;65:167-75.
14. Blank M, Ben-Bassat M, Shoenfeld Y. Modulation of SLE induction in naive mice by specific T cells with suppressor activity to pathogenic anti-DNA idiotype. Cell Immunol 1991;137:474-86.
15. Watts RA, Ravirajan CT, Staines NA, Isenberg DA. A human fetal monoclonal DNA-binding antibody shares idiotypes with fetal and adult murine monoclonal DNA binding antibodies. Immunology 1990;69:348-54.
16. Manheimer-Lory A, Monhian R, Splaver A, Gaynor B, Diamond B. Analysis of the V(kappa)I family: germline genes from an SLE patient and expressed autoantibody. Autoimmunity 1995;20:259-65.
17. Staines NA, Ward FJ, Meshi B, Eivazova E, Sutton BJ, McDonnell J, et al. Antibodies against DNA autoantibody idiotopes defined by idiopeptides appear in parallel with anti-double stranded DNA autoantibodies in systemic lupus erythematosus [abstract]. Arthritis Rheum 1995;38 Suppl 9:S298.
18. Ward FJ, Khan N, Wolger LJ, Howe CA, Eivazova ER, Harper N, et al. Immunogenic properties of an anti-DNA antibody derived peptide, 88H.64-80: location of a dominant idiotope defined by T and B cells. J Autoimmun 1998;11:439-47.
19. Williams WM, Staines NA, Muller S, Isenberg DA. Human T cell responses to autoantibody variable region peptides. Lupus 1995; 4:464-71.
20. Morgan A, Buchanan RRC, Lew AM, Olsen I, Staines NA. Five groups of antigenic determinants on DNA identified by monoclonal antibodies from (NZB × NZW)F1 and MRL/lpr/lpr mice. Immunology 1985;55:75-83.
21. Staines NA, Ravirajan CT, Morgan A, Belcher AJ, Henry AJ, Lake RA, et al. Expression and relationships of seven public idiotypes of DNA-binding autoantibodies on monoclonal antibodies and serum immunoglobulins. Lupus 1993;2:25-33.
22. Staines NA, Ward FJ, Denbury AN, Mitchiner J, Hartley O, Eilat D, et al. Primary sequence and location of the idiotopes of V-88, a DNA-binding monoclonal autoantibody, determined by idiotope scanning with synthetic peptides on pins. Immunology 1993;78: 371-8.
23. Sambrook J, Fritsch EF, Maniatis T. Molecular cloning: a laboratory manual. Cold Spring Harbor Laboratory Press, 1989.
24. Eivazova ER, Khalikov SH, Nekrasov AV, Borisova VN, Ismailov MI, Shahmatov AN. Induction of immune response by chemically synthesised FMDV protein VP1 fragments bound to a synthetic polymer support. Biomed Sci 1991;2:98-100.
25. Malmqvist M, Granzow R. Biomolecular interaction analysis. Methods 1994;6:95-8.
26. Haimovich J, Czerwinski D, Wong CP, Levy R. Determination of anti-idiotype antibodies by surface plasmon resonance. J Immunol Methods 1998;214:113-9.
27. Diaw L, Magnac C, Pritsch O, Burckle M, Alzari PM, Dighiero G. Structural and affinity studies of IgM polyreactive natural autoantibodies. J Immunol 1977;158:968-76.
28. Ward FJ, Knies JC, Cunningham C, Harris WJ, Staines NA. Natural antibodies that react with V region peptide epitopes of DNA-binding antibodies are made by mice with systemic lupus erythematosus as disease develops. Immunology 1997;92:354-61.
29. Hobby P, Ward FJ, Denbury AN, Williams DG, Staines NA, Sutton BJ. Molecular modelling of an anti-DNA autoantibody (V-88) and mapping of its V region epitopes recognised by heterologous and autoimmune antibodies. J Immunol 1998;161: 2944-52.
30. 2 antibody with DNA and other nuclear antigens. Arthritis Rheum 1997;40:109-23.
31. 1 mouse model of systemic lupus erythematosus. Arthritis Rheum 1993;36:355-64.
32. Madaio MP, Carlson J, Cataldo J, Ucci A, Migliorini P, Pankewycz O. Murine monoclonal anti-DNA antibodies bind directly to glomerular antigens and form immune deposits. J Immunol 1987; 138:2883-9.
33. Ohnishi K, Ebling FM, Mitchell B, Singh RR, Hahn BH, Tsao BT. Comparison of pathogenic and non-pathogenic murine antibodies to DNA-antigen binding and structural characteristics. Int Immunol 1994;6:817-30.
34. Jerne NK. Towards a network theory of the immune system. Ann Immunol 1974;12SC:373-89.
35. Jefferis R. What is an idiotype? Immunol Today 1993;14:119-21.
36. Corper AL, Sohi MK, Bonagura VR, Steinitz M, Jefferis R, Feinstein A. et al. Structure of human IgM rheumatoid factor Fab bound to its autoantigen IgG Fc reveals a novel topology of antibody-antigen interaction. Nat Struct Biol 1997;4:374-81.
37. Plotz PH. Autoantibodies are anti-idiotype antibodies to antiviral antibodies. Lancet 1983;2:824-6.
38. Elias D, Bone AJ, Baird JD, Cooke A, Cohen IR. Insulin-mimicking anti-idiotypic antibodies in development of spontaneous autoimmune diabetes in BB/E rats. Diabetes 1990;39: 1467-71.
39. Gavalchin J, Staines NA. T and B cell recognition of idiotypes of anti-DNA autoantibodies. Lupus 1997;6:337-43.
40. Eivazova ER, McDonnell JM, Sutton BJ, Staines NA. Antiidio-type antibodies with dual specificity for DNA and their potential pathogenecity in systemic lupus erythematosus [abstract]. Arthritis Rheum 1999;42:853.
41. Fricke H, Offen D, Mendlovic S, Shoenfeld Y, Bakimer R, Sperling J, et al. Induction of experimental systemic lupus erythematosus in mice by immunization with a monoclonal anti-La autoantibody. Int Immunol 1990;2:225-30.
42. Singh RR, Kurmar V, Ebling FM, Southwood S, Sette A, Sercarz EE, et al. T cell determinants from autoantibodies to DNA can upregulate autoimmunity in murine systemic lupus erythematosus. J Exp Med 1995;181:2017-27.
43. Howe CA, Hartley B, Williams GD, Muller S, Staines NA. Active immunizations with anti-DNA autoantibody idiopeptide 88H.64-80 is nephritogenic in (NZW × NZB)F1 and Balb/c mice [abstract]. Biochem Soc Trans 1997;3165.
44. Sibille P, Ternynck T, Nato F, Buttin G, Strosberg D, Avrameas A. Mimotopes of polyreactive anti-DNA antibodies identified using phage-display peptide libraries. Eur J Immunol 1997;27: 1221-8.
45. Putterman C, Diamond B. Immunization with a peptide surrogate for double-stranded DNA (dsDNA) induces autoantibody production and renal immunoglohulin deposition. J Exp Med 1998;188: 29-38.