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Volumn 14, Issue 6, 2000, Pages 1136-1142

Phase I/II study of 2-chloro-2'-deoxyadenosine with cyclophosphamide in patients with pretreated B cell chronic lymphocytic leukemia and indolent non-Hodgkin's lymphoma

Author keywords

2 chloro 2' deoxyadenosine; Chronic lymphocytic leukemia; Cladribine; Cyclophosphamide; Non Hodgkin's lymphoma

Indexed keywords

CISPLATIN; CLADRIBINE; CYCLOPHOSPHAMIDE; CYTARABINE; DEXAMETHASONE; DOXORUBICIN; ETOPOSIDE; FLUDARABINE; IFOSFAMIDE; MITOXANTRONE; PREDNISONE; PURINE NUCLEOSIDE DERIVATIVE; VINCRISTINE;

EID: 0034129880     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2401783     Document Type: Article
Times cited : (44)

References (44)
  • 1
    • 0002440308 scopus 로고    scopus 로고
    • Nucleoside analogs: Cellular pharmacology, mechanisms of action, and strategies for combination therapy
    • Cheson BD, Keating MJ, Plunkett W (eds). Marcel Dekker: New York
    • Plunkett W, Gandhi V. Nucleoside analogs: cellular pharmacology, mechanisms of action, and strategies for combination therapy. In: Cheson BD, Keating MJ, Plunkett W (eds). Nucleoside Analogs in Cancer Therapy. Marcel Dekker: New York, 1997, pp 1-35.
    • (1997) Nucleoside Analogs in Cancer Therapy , pp. 1-35
    • Plunkett, W.1    Gandhi, V.2
  • 3
    • 0030018146 scopus 로고    scopus 로고
    • Long-term survival following cladribine (2-chlorodeoxyadenosine) therapy in previously treated patients with chronic lymphocytic leukemia
    • Juliusson G, Liliemark J. Long-term survival following cladribine (2-chlorodeoxyadenosine) therapy in previously treated patients with chronic lymphocytic leukemia. Ann Oncol 1996; 7: 373-379.
    • (1996) Ann Oncol , vol.7 , pp. 373-379
    • Juliusson, G.1    Liliemark, J.2
  • 5
    • 0033017554 scopus 로고    scopus 로고
    • Effect of a 2-hour infusion of 2-chlorodeoxyadenosine in the treatment of refractory or previously untreated Waldenstrom's macroglobulinemia
    • Hellmann A, Lewandowski K, Zaucha JM, Bieniaszewska M, Halaburda K, Robak T. Effect of a 2-hour infusion of 2-chlorodeoxyadenosine in the treatment of refractory or previously untreated Waldenstrom's macroglobulinemia. Eur J Haematol 1999; 63: 35-41.
    • (1999) Eur J Haematol , vol.63 , pp. 35-41
    • Hellmann, A.1    Lewandowski, K.2    Zaucha, J.M.3    Bieniaszewska, M.4    Halaburda, K.5    Robak, T.6
  • 8
    • 0030949196 scopus 로고    scopus 로고
    • Intermittent infusion of cladribine (CdA) in previously treated patients with low-grade non-Hodgkin's lymphoma
    • Liliemark J, Porwit A, Juliusson G. Intermittent infusion of cladribine (CdA) in previously treated patients with low-grade non-Hodgkin's lymphoma. Leuk Lymphoma 1997; 25: 313-318.
    • (1997) Leuk Lymphoma , vol.25 , pp. 313-318
    • Liliemark, J.1    Porwit, A.2    Juliusson, G.3
  • 9
    • 15844368449 scopus 로고    scopus 로고
    • Multicentre prospective randomised trial of fludarabine vs cyclophosphamide, doxorubicin, and prednisone (CAP) for treatment of advanced-stage chronic lymphocytic leukaemia
    • French Cooperative Group on CLL. Multicentre prospective randomised trial of fludarabine vs cyclophosphamide, doxorubicin, and prednisone (CAP) for treatment of advanced-stage chronic lymphocytic leukaemia. Lancet 1996; 347: 1432-1438.
    • (1996) Lancet , vol.347 , pp. 1432-1438
  • 10
    • 0000431595 scopus 로고    scopus 로고
    • A randomized comparison of fludarabine and chlorambucil for patients with previously untreated chronic lymphocytic leukemia. a CALGB, SWOG, CTG/NCI-C and ECOG inter-group study
    • Rai KR, Peterson B, Elias L, Shepherd L, Hines J, Nelson D, Cheson B, Kolitz J, Schiffer CA. A randomized comparison of fludarabine and chlorambucil for patients with previously untreated chronic lymphocytic leukemia. A CALGB, SWOG, CTG/NCI-C and ECOG inter-group study. Blood 1996; 88: 141a.
    • (1996) Blood , vol.88
    • Rai, K.R.1    Peterson, B.2    Elias, L.3    Shepherd, L.4    Hines, J.5    Nelson, D.6    Cheson, B.7    Kolitz, J.8    Schiffer, C.A.9
  • 11
    • 0002460480 scopus 로고    scopus 로고
    • Multicentre prospective randomised trial of fludarabine vs chlorambucil and prednisone in previously untreated patients with active B-chronic lymphocytic leukaemia (B-CLL): Conclusive report
    • Spriano M, Chiurazzi F, Cassibba V, Montillo M, Liso V, Mazza P, Molica S, Bruni R, Clavio M, Gobbi M, Santini G. Multicentre prospective randomised trial of fludarabine vs chlorambucil and prednisone in previously untreated patients with active B-chronic lymphocytic leukaemia (B-CLL): conclusive report. Haematologica 1999; 84: 1091.
    • (1999) Haematologica , vol.84 , pp. 1091
    • Spriano, M.1    Chiurazzi, F.2    Cassibba, V.3    Montillo, M.4    Liso, V.5    Mazza, P.6    Molica, S.7    Bruni, R.8    Clavio, M.9    Gobbi, M.10    Santini, G.11
  • 13
    • 0030451076 scopus 로고    scopus 로고
    • In vitro cytotoxicity of 2-chlorodeoxyadenosine and chlorambucil in chronic lymphocytic leukemia
    • Begleiter A, Wang H, Verburg L, Lee K, Israels LC, Mowat MRA, Johnston JB. In vitro cytotoxicity of 2-chlorodeoxyadenosine and chlorambucil in chronic lymphocytic leukemia. Leukemia 1996; 10: 1959-1965.
    • (1996) Leukemia , vol.10 , pp. 1959-1965
    • Begleiter, A.1    Wang, H.2    Verburg, L.3    Lee, K.4    Israels, L.C.5    Mowat, M.R.A.6    Johnston, J.B.7
  • 14
    • 0029010158 scopus 로고
    • The influence of 2-chlorodeoxyadenosine (2-CdA) alone and in combination with cyclophosphamide or methotrexate on normal and leukemic hematopoiesis
    • Gora-Tybor J, Robak T. The influence of 2-chlorodeoxyadenosine (2-CdA) alone and in combination with cyclophosphamide or methotrexate on normal and leukemic hematopoiesis. Adv Exp Med Biol 1994; 370: 129-130.
    • (1994) Adv Exp Med Biol , vol.370 , pp. 129-130
    • Gora-Tybor, J.1    Robak, T.2
  • 15
    • 0023234707 scopus 로고
    • Formation and removal of crosslinks induced by melphalan and nitrogen mustard in relation to drug-induced cytotoxicity in human melanoma cells
    • Hansson JA, Lewensohn R, Ringborg U, Nilson B. Formation and removal of crosslinks induced by melphalan and nitrogen mustard in relation to drug-induced cytotoxicity in human melanoma cells. Cancer Res 1987; 47: 2631-2637.
    • (1987) Cancer Res , vol.47 , pp. 2631-2637
    • Hansson, J.A.1    Lewensohn, R.2    Ringborg, U.3    Nilson, B.4
  • 19
    • 0029859821 scopus 로고    scopus 로고
    • Fludarabine-mediated inhibition of nucleotide excision repair induces apoptosis in quiescent human lymphocytes
    • Sandoval A, Consoli U, Plunkett W. Fludarabine-mediated inhibition of nucleotide excision repair induces apoptosis in quiescent human lymphocytes. Clin Cancer Res 1996; 2: 1731-1741.
    • (1996) Clin Cancer Res , vol.2 , pp. 1731-1741
    • Sandoval, A.1    Consoli, U.2    Plunkett, W.3
  • 20
    • 0022622873 scopus 로고
    • Inhibition of DNA repair by deoxyadenosine in resting human lymphocytes
    • Seto S, Carrera CJ, Wasson B, Carson DA. Inhibition of DNA repair by deoxyadenosine in resting human lymphocytes. J Immunol 1986; 8: 2839-2843.
    • (1986) J Immunol , vol.8 , pp. 2839-2843
    • Seto, S.1    Carrera, C.J.2    Wasson, B.3    Carson, D.A.4
  • 21
    • 0031829418 scopus 로고    scopus 로고
    • In vitro chemosensitivity of chronic lymphocytic leukaemia to purine analogues - Correlation with clinical course
    • Bromidge TJ, Turner DL, Howe DJ, Johnson SA, Rule SA. In vitro chemosensitivity of chronic lymphocytic leukaemia to purine analogues - correlation with clinical course. Leukemia 1998; 12: 1230-1235.
    • (1998) Leukemia , vol.12 , pp. 1230-1235
    • Bromidge, T.J.1    Turner, D.L.2    Howe, D.J.3    Johnson, S.A.4    Rule, S.A.5
  • 22
    • 0033057078 scopus 로고    scopus 로고
    • Combination therapy with fludarabine and cyclophosphamide as salvage treatment in lymphoproliferative disorders
    • Frewin R, Turner D, Tighe M, Davies S, Rule S, Johnson S. Combination therapy with fludarabine and cyclophosphamide as salvage treatment in lymphoproliferative disorders. Br J Haematol 1999; 104: 612-613.
    • (1999) Br J Haematol , vol.104 , pp. 612-613
    • Frewin, R.1    Turner, D.2    Tighe, M.3    Davies, S.4    Rule, S.5    Johnson, S.6
  • 23
    • 0031841742 scopus 로고    scopus 로고
    • Clinical challenges in chronic lymphocytic leukemia
    • O'Brien S. Clinical challenges in chronic lymphocytic leukemia. Semin Hematol 1998; 35: 22-26.
    • (1998) Semin Hematol , vol.35 , pp. 22-26
    • O'Brien, S.1
  • 24
    • 0030733897 scopus 로고    scopus 로고
    • Combined therapy with fludarabine and cyclophosphamide in relapsed/resistant patients with B-cell chronic lymphocytic leukaemia and non-Hodgkin's lymphomas
    • Zaja F, Rogato A, Russo D, Marin L, Silvestri F, Baccarani M. Combined therapy with fludarabine and cyclophosphamide in relapsed/resistant patients with B-cell chronic lymphocytic leukaemia and non-Hodgkin's lymphomas. Eur J Haematol 1997; 59: 327-328.
    • (1997) Eur J Haematol , vol.59 , pp. 327-328
    • Zaja, F.1    Rogato, A.2    Russo, D.3    Marin, L.4    Silvestri, F.5    Baccarani, M.6
  • 25
    • 0343028105 scopus 로고    scopus 로고
    • Combination of fludarabine and cyclophosphamide as a salvage regimen for lymphoma - Experience with 27 patients
    • Gillis S, Lossos I, Libster D, Paltiel O, Polliack A. Combination of fludarabine and cyclophosphamide as a salvage regimen for lymphoma - experience with 27 patients. Haematologica 1999; 84: 652.
    • (1999) Haematologica , vol.84 , pp. 652
    • Gillis, S.1    Lossos, I.2    Libster, D.3    Paltiel, O.4    Polliack, A.5
  • 27
    • 0028022841 scopus 로고
    • Concomitant administration of chlorambucil limits dose intensity of fludarabine in previously treated patients with chronic lymphocytic leukemia
    • Weiss M, Spiess T, Berman E, Kcmpin S. Concomitant administration of chlorambucil limits dose intensity of fludarabine in previously treated patients with chronic lymphocytic leukemia. Leukemia 1994; 8: 1290-1293.
    • (1994) Leukemia , vol.8 , pp. 1290-1293
    • Weiss, M.1    Spiess, T.2    Berman, E.3    Kcmpin, S.4
  • 28
    • 0028231835 scopus 로고
    • Phase I study of combined 2-chlorodeoxyadenosine and chlorambucil in chronic lymphoid leukemia and low-grade lymphoma
    • Tefferi A, Witzig TE, Reid JM, Li C-Y, Ames M. Phase I study of combined 2-chlorodeoxyadenosine and chlorambucil in chronic lymphoid leukemia and low-grade lymphoma. J Clin Oncol 1994; 12: 569-574.
    • (1994) J Clin Oncol , vol.12 , pp. 569-574
    • Tefferi, A.1    Witzig, T.E.2    Reid, J.M.3    Li, C.-Y.4    Ames, M.5
  • 29
    • 0345238896 scopus 로고    scopus 로고
    • Cladribine with cyclophosphamide and prednisone in the management of low-grade lymphoproliferative malignancies
    • Laurencet FM, Zulian GB, Guetty-Alberto M, Iten PA, Betticher DC, Alberto P. Cladribine with cyclophosphamide and prednisone in the management of low-grade lymphoproliferative malignancies. Br J Cancer 1999; 79: 1215-1219.
    • (1999) Br J Cancer , vol.79 , pp. 1215-1219
    • Laurencet, F.M.1    Zulian, G.B.2    Guetty-Alberto, M.3    Iten, P.A.4    Betticher, D.C.5    Alberto, P.6
  • 30
    • 0023717101 scopus 로고    scopus 로고
    • National Cancer Institute-sponsored Working Group guidelines for clinical protocols for chronic lymphocytic leukemia: Revised guidelines for diagnosis and treatment
    • Cheson BD, Bennett JM, Grever M, Kay N, Keating MJ, O'Brien S, Rai KR. National Cancer Institute-sponsored Working Group guidelines for clinical protocols for chronic lymphocytic leukemia: revised guidelines for diagnosis and treatment. Am J Hematol 1996; 29: 152-163.
    • (1996) Am J Hematol , vol.29 , pp. 152-163
    • Cheson, B.D.1    Bennett, J.M.2    Grever, M.3    Kay, N.4    Keating, M.J.5    O'Brien, S.6    Rai, K.R.7
  • 32
    • 0030013103 scopus 로고    scopus 로고
    • Cladribine and mitoxantrone dose escalation in indolent non-Hodgkin's lymphoma
    • Saven A, Lee T, Kosty M, Piro L. Cladribine and mitoxantrone dose escalation in indolent non-Hodgkin's lymphoma. Leukemia 1996; 14: 2139-2144.
    • (1996) Leukemia , vol.14 , pp. 2139-2144
    • Saven, A.1    Lee, T.2    Kosty, M.3    Piro, L.4
  • 33
    • 0029804405 scopus 로고    scopus 로고
    • 2-Chloro-2′-deoxyadenosine: Clinical applications in hematology
    • Delannoy A. 2-Chloro-2′-deoxyadenosine: clinical applications in hematology. Blood Rev 1996; 10: 148-166.
    • (1996) Blood Rev , vol.10 , pp. 148-166
    • Delannoy, A.1
  • 34
    • 0028265320 scopus 로고
    • Retreatment of chronic lymphocytic leukemia with 2-chlorodeoxyadenosine (CdA) at relapse following CdA-induced remission: No acquired resistance
    • Juliusson G, Liliemark J. Retreatment of chronic lymphocytic leukemia with 2-chlorodeoxyadenosine (CdA) at relapse following CdA-induced remission: no acquired resistance. Leuk Lymphoma 1994; 13: 75-80.
    • (1994) Leuk Lymphoma , vol.13 , pp. 75-80
    • Juliusson, G.1    Liliemark, J.2
  • 35
    • 0026675806 scopus 로고
    • Response to 2-chlorodeoxyadenosine in patients with B-cell chronic lymphocytic leukemia resistant to fludarabine
    • luliusson G, Elmhorn-Rosenborg A, Liliemark J. Response to 2-chlorodeoxyadenosine in patients with B-cell chronic lymphocytic leukemia resistant to fludarabine. New Engl J Med 1992; 327: 1056-1061.
    • (1992) New Engl J Med , vol.327 , pp. 1056-1061
    • Luliusson, G.1    Elmhorn-Rosenborg, A.2    Liliemark, J.3
  • 37
    • 0343928115 scopus 로고    scopus 로고
    • Primary treatment of Waldenstrom's macroglobulinemia with subcutaneous 2-chlorodeoxyadenosine and oral cyclophosphamide
    • Weber DM, Delasalle K, Gavino M, Wood A, Cabanillas F, Alexenian R. Primary treatment of Waldenstrom's macroglobulinemia with subcutaneous 2-chlorodeoxyadenosine and oral cyclophosphamide. Blood 1997; 90: 1592.
    • (1997) Blood , vol.90 , pp. 1592
    • Weber, D.M.1    Delasalle, K.2    Gavino, M.3    Wood, A.4    Cabanillas, F.5    Alexenian, R.6
  • 38
    • 0033011668 scopus 로고    scopus 로고
    • Salvage chemotherapy using a combination of fludarabine and cyclophosphamide for refractory or relapsing non-Hodgkin's lymphoma
    • Lossos IS, Paltiel O, Polliack A. Salvage chemotherapy using a combination of fludarabine and cyclophosphamide for refractory or relapsing non-Hodgkin's lymphoma. Leuk Lymphoma 1999; 33: 155-160.
    • (1999) Leuk Lymphoma , vol.33 , pp. 155-160
    • Lossos, I.S.1    Paltiel, O.2    Polliack, A.3
  • 40
    • 0008671766 scopus 로고    scopus 로고
    • Prolonged time to progression (TTP) in patients with low grade lymphoma (LGL) treated with cyclophosphamide (C) and fludarabine (F)
    • Hochster H, Oken M, Winter J, Gordon L, Raphael B, Bennett J, Horning S, Cassileth P. Prolonged time to progression (TTP) in patients with low grade lymphoma (LGL) treated with cyclophosphamide (C) and fludarabine (F). Proc Am Soc Clin Oncol 1998; 17: 66.
    • (1998) Proc am Soc Clin Oncol , vol.17 , pp. 66
    • Hochster, H.1    Oken, M.2    Winter, J.3    Gordon, L.4    Raphael, B.5    Bennett, J.6    Horning, S.7    Cassileth, P.8
  • 42
    • 0344867044 scopus 로고    scopus 로고
    • 2-chlorodeoxyadenosine (cladribine) in the treatment of patients with chronic lymphocytic leukemia 55 years old or younger
    • Robak T, Blonski JZ, Urbanska-Rys H, Blasinska-Morawiec M, Skotnicki AB. 2-chlorodeoxyadenosine (cladribine) in the treatment of patients with chronic lymphocytic leukemia 55 years old or younger. Leukemia 1999; 13: 518-523.
    • (1999) Leukemia , vol.13 , pp. 518-523
    • Robak, T.1    Blonski, J.Z.2    Urbanska-Rys, H.3    Blasinska-Morawiec, M.4    Skotnicki, A.B.5
  • 44
    • 0032812729 scopus 로고    scopus 로고
    • Second malignancies as a consequence of nucleoside analog therapy for chronic lymphoid leukemias
    • Cheson BD, Vena DA, Barett J, Freidlin B. Second malignancies as a consequence of nucleoside analog therapy for chronic lymphoid leukemias. J Clin Onco/ 1999; 17: 2454-2460.
    • (1999) J Clin Onco , vol.17 , pp. 2454-2460
    • Cheson, B.D.1    Vena, D.A.2    Barett, J.3    Freidlin, B.4


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