Pharmacokinetics of fleroxacin in horses

Journal of Veterinary Pharmacology and Therapeutics

Volumn 23, Issue 2, 2000, Pages 103-105

  Rebuelto, M ^a   Otero, P ^a   Albarellos, G ^a   Ambros, L ^a   Kreil, V ^a   Waxman, S ^a   Montoya, L ^a   Hallu, R ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

[No Author keywords available]

Indexed keywords

FLEROXACIN;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG ELIMINATION; DRUG HALF LIFE; HORSE; MEAN RESIDENCE TIME; NONHUMAN; PRIORITY JOURNAL; REGRESSION ANALYSIS;

ADMINISTRATION, ORAL; ANIMALS; ANTI-INFECTIVE AGENTS; AREA UNDER CURVE; BIOLOGICAL AVAILABILITY; FLEROXACIN; HALF-LIFE; HORSES; INJECTIONS, INTRAVENOUS; LINEAR MODELS; METABOLIC CLEARANCE RATE;

ANIMALIA; EQUIDAE; EQUUS CABALLUS;

EID: 0034129134     PISSN: 01407783     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2885.2000.00248.x     Document Type: Article

References (12)

1. Bennet, J.V., Brodie J.L., Bennet, E.J. & Kirby, W.M. (1966) Simplified, accurate method for antibiotic assay of clinical specimens. Applied Microbiology, 14, 170-177.
2. Brown, S.A. (1996) Fluoroquinolones in animal health. Journal of Veterinary Pharmacology and Therapeutics, 19, 1-14.
3. Dowling, P.M., Wilson, R.C., Tyler, J.W. & Duran, S.H. (1995) Pharmacokinetics of ciprofloxacin in ponies. Journal of Veterinary Pharmacology and Therapeutics, 18, 7-12.
4. Giguere, S., Sweeney, R. & Belanger, M. (1996) Pharmacokinetics of enrofloxacin in adult horses and concentration of the drug in serum, body fluids, and endometrial tissues after repeated intragastrically administered doses. American Journal of Veterinary Research, 57, 1025-1030.
5. Hirai, K., Aoyama, H., Hosaka, M., Oomori, Y., Niowaka, Y., Suzne, S. & Irikurah, T. (1986) In vitro and in vivo antibacterial activity of AM 833, a new quinolone derivative. Antimicrobial Agents and Chemotherapeutics, 30, 1059-1066.
6. Kaartinen, L., Panu, S. & Pyorala, S. (1997) Pharmacokinetics of enrofloxacin in horses after single intravenous and intramuscular administration. Equine Veterinary Journal, 29, 378-381.
7. Kusajima, H., Ishikawa, N., Machida, M., Uchida, H. & Irikura, T. (1986) Pharmacokinetics of a New Quinolone, AM-833, in Mice, Rats, Rabbits, Dogs and Monkeys. Antimicrobial Agents and Chemotherapeutics, 30, 304-309.
8. Manek, N., Andrews, J.M. & Wise, R. (1986) In vitro activity of Ro 23-6240, a new trifluorinated quinolone derivative, compared with that of other antimicrobial agents. Antimicrobial Agents and Chemotherapeutics, 30, 330-332.
9. Mevius, D.J., Breukink, H.J., Guelen. P.J.M., Jansen, T. & De Greve, B. (1990) Pharmacokinetics, metabolism and renal clearance of flumequine in veal calves. Journal of Veterinary Pharmacology and Therapeutics, 13, 159-169.
10. Reigner, B.G. & Welker, H.A. (1996) Factors Influencing Elimination and Distribution of Fleroxacin: Metaanalysis of Individual Data from 10 Pharmacokinetic Studies. Antimicrobial Agents and Chemotherapeutics, 40, 575-580.
11. Weidekamm, E., Portman, R., Suter, K., Partos, C., Dell, D. & Lucker, P. (1987) Single-and Multiple-Dose Pharmacokinetics of fleroxacin, a Trifluorinated Quinolone, in Humans. Antimicrobial Agents and Chemotherapeutics, 31, 1909-1914.
12. Wise, R., Kirkpatrick, J.A. & Griggs, D.J. (1987) Pharmacokinetics and Tissue Penetration of Ro 23-6240, a New Trifluoroquinolone. Antimicrobial Agents and Chemotherapeutics, 31, 161-163.