Decreased carnitine biosynthesis in rats with secondary biliary cirrhosis

Hepatology

Volumn 31, Issue 6, 2000, Pages 1217-1223

  Krahenbuhl, Stephan ^a,b   Brass, Eric P ^a,c   Hoppel, Charles L ^a,d  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

^b UNIVERSITY HOSPITAL BASEL   (Switzerland)

^c HARBOR UCLA MEDICAL CENTER   (United States)

^d LOUIS STOKES CLEVELAND VA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARNITINE; GAMMA BUTYROBETAINE; LONG CHAIN FATTY ACID; LYSINE DERIVATIVE;

AMINO ACID SYNTHESIS; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILIARY CIRRHOSIS; BILIARY TRACT DISEASE; BIOSYNTHESIS; CONTROLLED STUDY; FATTY ACID TRANSPORT; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; URINARY EXCRETION;

EID: 0034128354     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1053/jhep.2000.8105     Document Type: Article

References (9)

1. Bremer J. Carnitine - metabolism and functions. Physiol Rev 1983;63:1421-1466.
2. Fritz I. The effects of muscle extracts on the oxidation of palmitic acid by liver slices and homogenates. Acta Physiol Scand 1955;34:367-385.
3. Bieber LL, Emaus R, Valkner K, Farrell S. Possible functions of short-chain and medium-chain carnitine acyltransferases. Fed Proc 1982;41:2858-2862.
4. Brass EP, Hoppel CL. Relationship between acid-soluble carnitine and coenzyme A pools in vivo. Biochem J 1980;190:495-504.
5. Feller AG, Rudman D. Role of carnitine in human nutrition. J Nutr 1988;118:541-547.
6. Paik WK, Kim S. Protein methylation: chemical, enzymological, and biological significance. Adv Enzymol Relat Areas Mol Biol 1975:42:227-286.
7. Hoppel CL, Davis AT. Inter-tissue relationships in the synthesis and distribution of carnitine. Biochem Soc Trans 1986;14:673-674.
8. Rebouche CJ, Lehman LJ, Olson AL. e-N-Trimethyllysine availability regulates the rate of carnitine biosynthesis in the growing rat. J Nutr 1986;116:751-759.
9. Rebouche CJ, Bosch EP, Chenard CA, Schabold KJ, Nelson SE. Utilization of dietary precursors for carnitine synthesis in human adults. J Nutr 1989;119:1907-1913.