Exercise immunology: Neuroendocrine regulation of NK-cells

International Journal of Sports Medicine, Supplement

Volumn 21, Issue 1, 2000, Pages

  Jonsdottir, I H ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

Catecholamines; Endogenous opioids; Exercise; HPA axis; NK cells

Indexed keywords

CATECHOLAMINE DERIVATIVE; GLUCOCORTICOID; GROWTH HORMONE; OPIATE RECEPTOR;

ARTICLE; AUTONOMIC NERVOUS SYSTEM; CENTRAL NERVOUS SYSTEM; CYTOTOXICITY; EXERCISE; HUMAN; HYPOTHALAMUS HYPOPHYSIS SYSTEM; IMMUNE SYSTEM; NATURAL KILLER CELL; NEUROENDOCRINE SYSTEM;

AFFERENT PATHWAYS; ANIMALS; EXERCISE; HUMANS; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; IMMUNITY, NATURAL; KILLER CELLS, NATURAL; NEUROIMMUNOMODULATION; OPIOID PEPTIDES; PITUITARY-ADRENAL SYSTEM; RATS;

EID: 0034128231     PISSN: 0943917X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (47)

1. Baslund B, Lyngberg K, Andersen V, Halkjaer-Kristensen J, Hansen M, Klokker M, Pedersen BK. Effect of 8 wk of bicycle training on the immune system of patients with rheumatoid arthritis. J Appl Physiol 1993; 75 (4): 1691-1695
2. Bellinger DL, Felten SY, Lorton D, Felten DL. Origin of noradrenergic innervation of the spleen in rats. Brain, Behavior and Immunity 1989; 3: 291-311
3. 2-Adrenergic stimulation causes detachment of natural killer cells from cultured endothelium. Eur J Immunol 1993; 23: 3242-3247
4. Besedovsky HO, Del Ray A, Sorkin E, Da Prada M, Keller HH. Immunoregulation mediated by the sympathetic nervous system. Cell Immunol 1979; 48: 346-355
5. Blake MJ, Stein EA, Vomachka AJ. Effects of exercise training on brain opioid peptides and serum LH in female rats. Peptides 1984; 5: 953-958
6. Blalock JE, Bost KL, Smith EM. Neuroendocrine peptide hormones and their receptors in the immune system. J Neuroimmunol 1985; 10: 31-40
7. Carr DJJ. The role of endogenous opioids and their receptors in the immune system. Proc Soc Experm Biolog Med 1991; 198: 710-720
8. Christ DM, Mackinnon LT, Thompson RF, Atterbom HA, Egan PA. Physical exercise increases natural cellular-mediated tumor cytotoxicity in elderly women. Gerontology 1989; 35: 66-71
9. Croiset G, Heijnen CJ, van der Wal WE, de Boer SF, de Wied D. A role for the autonomic nervous system in modulating the immune response during mild emotional stimuli. Life Sci 1990; 46: 419-425
10. de Meirleir K, Naaktgeboren N, Van Steirteghem A, Gorus F, Olbrecht J, Block P. β-Endorphin and ACTH levels in peripheral blood during and after aerobic and anaerobic exercise. Eur J Appl Physiol 1986; 55: 5-8
11. Farrell PA, Kjaer M, Bach FW, Calbo H. β-Endorphin and adrenocorticotropin response to supramaximal treadmill exercise in trained and untrained males. Acta Physiol Scand 1987; 130: 619-625
12. Felten DL, Felten SY, Bellinger DL, Carlson SL, Ackerman KD, Madden KS, Olschowki JA, Livnat S. Noradrenergic sympathetic neural interactions with the immune system: structure and function. Immunological Reviews 1987; 100: 225-260
13. 3H]-dihydroprenolol binding to human polymorphonuclear particulates. J Lab Clin Med 1978; 92: 613-618
14. Gannon GA, Shek PN, Shephard RJ. Natural killer cells: Modulation by intensity and duration of exercise. Exerc Immunol Rev 1995; 1: 26-48
15. Gatti G, Masera RG, Pallavicini L, Sartori ML, Staurenghi A, Orlandi F, Angeli A. Interplay in vitro between ACTH, β-endorphin, and glucocorticoids in the modulation of spontaneous and lymphokine-inducible human natural killer (NK) cell activity. Brain Behav Immun 1993; 7: 16-28
16. Heijnen CJ, Kavelaars A, Ballieux RE. β-Endorphin: cytokine and neuropeptide. Immunol Rev 1991; 119: 42-63
17. Herberman RB, Reynolds CW, Ortaldo JR. Mechanism of cytotoxictiy by natural killer (NK) cells. Ann Rev Immunol 1986; 4: 651-680
18. Hoffmann P, Terenius L, Thorén P. Cerebrospinal fluid immunoreactive β-endorphin concentration is increased by voluntary exercise in spontaneously hypertensive rat. Regulatory Peptides 1990; 28: 233-239
19. Jankovic BD, Radulovic J. Enkephalins, brain and immunity: Modulation of immune responses by methionine-enkephalin injected into the cerebral cavity. Intern J Neuroscience 1992; 67: 241-270
20. Jonsdottir IH, Asea A, Hoffmann P, Hellstrand K, Thorén P. Voluntary chronic exercise augments in vivo cytotoxicity in rats. J Appl Physiol 1996; 80: 1799-1803
21. Jonsdottir IH, Johansson C, Asea A, Johansson P, Hellstrand K, Thorén P, Hoffmann P. Duration and mechanism of the increased natural cytotoxicity seen after chronic voluntary exercise in rats. Acta Physiol Scand 1997; 160: 333-339
22. Kay N, Allen J, Morley JE. Endorphins stimulate normal human peripheral blood lymphocyte natural killer activity. Life Sciences 1984; 35: 53-59
23. Lewis CE, McGee JO. Natural killer cells in tumour biology. In: Lewis CE, McGee JO (eds). The Natural Killer Cell. Oxford: IRL press at Oxford university press, 1992: 175-203
24. MacNeil B, Hoffman-Goetz L. Chronic exercise enhances in vivo and in vitro cytotoxic mechanisms of natural immunity in mice. J Appl Physiol 1993; 74: 388-395
25. Madden KS, Felten DL. Experimental basis for neural-immune interactions. Physiological Reviews 1995; 75: 77-106
26. Mandler RN, Biddison WE, Mandler R, Serrate SA. β-Endorphin augments the cytolytic activity and interferon production of natural killer cells. J Immunol 1986; 136 (3): 934-939
27. Mathews PM, Froelich CJ, Sibbitt WL, Bankhurst AD. Enhancement of natural cytotoxicity by β-endorphin. J Immunol 1983; 130: 1658-1662
28. Metzger JM, Stein EA. β-Endorphin and sprint training. Life Sci 1984; 34: 1541-1547
29. Mitchell JH. Neural control of the circulation during exercise. Med Sci Sports Exerc 1990; 22: 141-154
30. Morley JE, Kay NE, Solomon GF, Plotnikoff NP. Neuropeptides: Conductors of the immune orchestra. Life Sciences 1987; 41: 527-544
31. Mörch H, Pedersen BK. β-Endorphin and the immune system-possible role in autoimmune diseases. Autoimmunity 1995; 21: 161-171
32. Nieman DC, Henson DA, Gusewitch G, Warren BJ, Dotson RC, Butterworth DE, Nehlsen-Cannarella SL. Physical activity and immune function in elderly women. Med Sci Sports Exerc 1993; 25: 823-831
33. Nieman DC, Miller AR, Henson DA, Warren BJ, Gusewitch G, Johnson RL, Nehlsen-Cannarella SL Effects of high-vs. moderate-intensity exercise on natural killer cell activity. Med Sci Sports Exerc 1993; 25 (10): 1126-1134
34. Nieman DC, Nehlsen-Cannarella SL, Markoff PA, Balk-Lamberton AJ, Yang H, Chritton DBW, Lee JW, Arabatzis K. The effects of moderate exercise training on natural killer cells and acute upper respiratory tract infections. Int J Sports Med 1990; 11: 467-473
35. O'Shea J, Ortaldo JR. The biology of natural killer cells: insights into the molecular basis of function. In: Lewis CE, McGee JO (eds). The Natural Killer Cell. Oxford: Oxford University Press, 1992; 1: 2-40
36. Pedersen BK, Nielsen HB. Acute exercise and the immune system. In: Pedersen BK (ed). Exercise Immunology. Heidelberg, Germany: Springer, 1997; 2: 5-38
37. Przewlocki R. Opioid systems and stress. In: Herz A (ed). Opioids II. Berlin, Heidelberg: Springer-Verlag, 1993; 42: 293-324
38. Rouveix B. Opiates and immune function. Therapie 1992; 47: 503-512
39. Trinchieri G. Biology of natural killer cells. Adv Immunol 1989; 47: 187-376
40. Tvede N, Kappel M, Halkjaer-Kristensen J, Galbo H, Pedersen BK. The effect of light, moderate and severe bicycle exercise on lymphocyte subsets, natural and lymphokine activated killer cells, lymphocyte proliferative response and interleukin-2 production. Int J Sports Med 1993; 14 (5): 275-282
41. Ullum H, Palmö J, Halkjaer-Kristensen J, Diamant M, Klokker M, Kruuse A, LaPerriere A, Klarlund Pedersen B. The effect of acute exercise on lymphocyte subsets, natural killer cells, proliferative responses, and cytokines in HIV-seropositive persons. J Acquir Immune Defic Syndr 1994; 7: 1122-1133
42. Wan W, Vriend CY, Wetmore L, Gartner JG, Greenberg AH, Nance DM. The effects of stress on splenic immune function are mediated by the splenic nerve. Brain Res Bull 1993; 30: 101-105
43. Weber RJ, Pert A. The periaqueductal gray matter mediates opiate-induced immunosuppression. Science 1989; 245: 188-190
44. Weigent DA, Blalock JE. Interactions between the neuroendocrine and immune systems: Common hormones and receptors. Immunological Reviews 1987; 100: 79-108
45. Weigent DA, Blalock JE. Associations between the neuroendocrine and immune systems. J Leukocyte Biol 1995; 57: 137-150
46. Welsh RM, Vargas-Cortes M. Natural killer cells in viral infections. In: Lewis CE, McGee JO (eds). The natural killer cell. Oxford: Oxford University Press, 1992; 4: 107-150
47. Wilmore JH, Costill DL. Physiology of sport and exercise. Champaign, USA: Human Kinetics, 1994