Coexpression of PTHrP and PTH/PTHrP receptor in a myoepithelial cell line derived from normal human breast

Folia Histochemica et Cytobiologica

Volumn 38, Issue 2, 2000, Pages 65-69

  Sopel, Mirosław ^a   Lis, Anna ^a  

^a WROCLAW MEDICAL UNIVERSITY   (Poland)

Author keywords

Mammary gland; Myoepithelial cells; Parathyroid hormone related peptide receptor; Parathyroid hormone related protein (PTHrP)

Indexed keywords

MESSENGER RNA; PARATHYROID HORMONE RECEPTOR; PARATHYROID HORMONE RELATED PROTEIN;

ARTICLE; CELL LINE; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; MAMMARY GLAND; MYOEPITHELIUM CELL; NORMAL HUMAN; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; PROTEIN TARGETING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 0034127802     PISSN: 00155586     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Abou-Samra AB, Jüppner H, Force T, Freeman M, Kong X-F, Schipani E, Urena P, J. Richards J, Bonventre JV, Potts JT, Kronenberg HM, Serge GV (1992) Expression cloning of a common receptor for parathyroid hormone and parathyroid hormone-related peptide from rat osteoblast-like cells: a single receptor stimulates intracellular accumulation of both cAMP and inositol triphosphates and increases intracellular free calcium. Proc Natl Acad Sci USA 89: 2732-2736
2. Bouizar Z, Spyratos F, Deytieux S, de Vernejoul MC, Jullienne A (1996) Polymerase chain reaction analysis of parathyroid hormone-related protein gene expression in breast cancer patients and occurence of bone metastases. Cancer Res 53: 5076-5078
3. Broadus AE, Mangin M, Ikeda K, Insogna KL, Weir EC, Burtis WJ, Stewart AF (1988) Humoral hypercalcemia of cancer. N Engl J Med 319: 556-563
4. Crass MF, Scarpace PJ (1993) Vasoactive properties of a parathyroid hormone-related protein in the rat aorta. Peptides 14: 179-183
5. De Papp AE, Stewart AF (1993) Parathyroid hormone-related protein; a peptide of diverse physiologic functions. Trends Endocrinol Metab 4: 181-187
6. Downey SE, Hoyland J, Freemont AJ, Knox F, Walls J, Bundred NJ (1997) Expression of the receptor for parathyroid hormone-related protein in normal and malignant breast tissue. J Pathol 183: 212-217
7. Ferrari SL, Rizzoli R, Chaponnier C, Gabbiani G, Bonjour JP (1993) Parathyroid hormone-related protein increases cAMP production in mammary epithelial cells. Am J Physiol 264: 471-475
8. Gelbert L, Schipani E, Jüppner H, Abou-Samra AB, Serge GV, Naylor S, Drabkin H, Heath H (1994). Chromosomal localization and the parathyroid hormone/parathyroid hormone-related protein receptor gene to human chromosome 3p21.1-p24.2. J Clin Endocrinol Metab 79: 1046-1048
9. Hackett A, Smith HS, Springer EL, Owens RB, Nelson-Rees WA, Riggs JL, Gardner MB (1977) Two syngenetic cell lines from human breast tissue: the aneuploid mammary epithelial (Hs578T) and the diploid myoepithelial (Hs578Bst) cell lines. J Natl Cancer Inst 58: 1795-1800
10. Iezzoni JC, Bruns ME, Frierson HF, Scott MG, Pence RA, Deftos LJ, Bruns DE (1998) Coexpression of parathyroid hormone-related protein and its receptor in breast carcinoma: a potential autocrine effector system. Mod Pathol 11: 265-270
11. Ingleton PM, Danks JA (1996) Distribution and function of parathyroid hormone-related protein in vertebrate cells. Int Rev Cytol 166: 231-280
12. Luparello C, Burtis WJ, Raue F, Birch MA, Gallagher A (1995) Parathyroid hormone-related peptide and 8701-BC breast cancer cell growth and invasion in vitro: evidence for growth-inhibiting and invasion-promoting effects. Mol Cell Endocrinol 111: 225-232
13. Martin TJ, Moseley JM, Gilespie MT (1991) Parathyroid hormone related protein: biochemistry and molecular biology. Crit Rev Biochem Mol Biol 26: 377-395
14. Massfelder T, Fiaschi Taesch N, Stewart AF, Helwig JJ (1998) Parathyroid hormone-related peptide - a smooth muscle tone and proliferation regulatory protein. Curr Opin Nephrol Hypertens 7: 27-32
15. Moore DM, Vogl AW, Baimbridge K, Emerman MJ (1987) Effect of calcium on oxytocin-induced contraction of mammary gland myoepithelium as visualized by NBD-phallicidin. J Cell Sci 88:563-569
16. Nickols GA, Nana AD, Nichols MA, Dipette DJ, Asimakis GK (1989) Hypotension and cardiac stimulation due to the parathyroid hormone-related protein, humoral hypercalcaemia of malignancy factor. Endocrinology 125: 834-841
17. Orloff JJ, Ganz MB, Nathanson MH, Moyer MS, Kats Y, Mitnick M, Behal A, Gasalla-Herraiz J, Isales CM (1996). A midregion parathyroid hormone-related peptide mobilizes cytosolic calcium and stimulates formation of inositol triphosphate in a squamous carcinoma cell line. Endocrinology 137: 5376-5385
18. Orloff JJ, Kats Y, Urena P, Schipani E, Vasavada RC, Philbrick WM, Behal A, Abou-Samra AB, Serge GV, Jüppner H (1995). Further evidence for a novel receptor for amino-terminal parathyroid hormone-related protein on keratinocytes and squamous carcinoma cell lines. Endocrinology 136: 3016-3023
19. Philbrick WM, Wysolmerski JJ, Galbraith S, Orloff JJ, Yang KH, Vasavada RC, Weir EC, Broadus AE, Stewart AF (1996) Defining the roles of parathyroid hormone-related protein in normal physiology, Physiol Rev 76: 127-173
20. Pirola CJ, Wang HM, Kamyar A, Wu S, Enomoto H, Sharifi B, Forrester JS, Clemens TL, Fagin JA (1993) Angiotensin II regulates parathyroid hormone-related protein expression in cultured rat aortic smooth muscle cells through transcriptional and posttranscriptional mechanisms. J Biol Chem 268: 1987-1994
21. Rakopoulos M, Vargas SJ, Gillespie MT, Ho PMW, Difenbach-Jagger H, Leaver DD, Grill V, Moseley JM, Danks JA, Martin TJ (1992) Production of parathyroid hormone-related protein by the mammary gland in pregnancy and lactation. Am J Physiol 263: 1077-1085
22. Robinson SD, Silberstein GB, Roberts AB, Flanders KC, Daniel CW (1991) Regulated expression and growth inhibitory effects of transforming growth factor-β isoforms in mouse mammary gland development. Development 113: 867-878
23. Seitz PK, Cooper KM, Ives KL, Ishizuka J, Townsend C, Rajaraman S, Cooper CW (1993) Parathyroid hormone-related peptide production and action in myoepithelial cell line derived from normal human breast. Endocrinology 133: 1116-1124
24. Soifer NE, Dee KE, Insogna KL, Burtis WJ, Matovcik LM, Wu TL, Milstone LM, Broadus AE, Philbrick WM, Stewart AF (1992) Parathyroid hormone-related peptide: evidence for secretion of a novel mid-region fragment by three different cell lines in culture. J Biol Chem 267: 18236-18243
25. Sopel M (1995) Electron-microscopic cytochemical localization of adenylate cyclase activity in the myoepithelial cells of the lactating mouse mammary gland. Cell Tissue Res 279: 441-444
26. Suva LA, Winslow GA, Wettenhall REH, Hammonds RG, Moseley JM, Diefenbach-Jagger H, Rodda CP, Kemp BE, Rodigruez H, Chen EY, Hudson PJ, Martin TJ, Wood WI (1987) A parathyroid hormone-related protein implicated in malignant hypercalcemia: Cloning and expression. Science 237: 893-896
27. Thiede MA (1994) Parathyroid hormone-related protein a regulated calcium-mobilizing product of the mammary gland. J Dairy Sci 77: 1952-1963
28. Thiede MA, Rodan GA (1988) Expression of a calcium mobilizing parathyroid hormone-like peptide in lactating mammary tissue. Science 242: 278-280
29. Williams JM, Daniel CW (1983) Mammary ductal elongation: differentiation of myoepithelium and basal lamina during branching morphogenesis. Dev Biol 97: 274-290
30. Wysolmerski JJ, McCaughern-Carucci J, Daifotis A, Broadus A, Philbrick W (1995) Overexpression of parathyroid hormone-related protein or parathyroid hormone in transgenic mice impairs branching morphogenesis during mammary gland development. Development 121: 3539-3547
31. Wysolmerski JJ, Philbrick WM, Dunbar ME, Lanske B, Kronenberg H, Broadus AE (1998) Rescue of the parathyroid hormone-related protein knockout mouse demonstrates that parathyroid hormone-related protein is essential for mammary gland development. Development 125: 1285-1294