Deletion polymorphism of angiotensin-converting enzyme gene is associated with postprandial hyperglycaemia in individuals undergoing general check-up

Clinical and Experimental Pharmacology and Physiology

Volumn 27, Issue 7, 2000, Pages 483-487

  Ohishi, Mitsuru ^a   Rakugi, Hiromi ^a   Miki, Tetsuro ^a   Katsuya, Tomohiro ^a   Okamura, Atsunori ^a   Kamide, Kei ^a   Nakata, Yukiko ^a   Takami, Seiju ^a   Ikegami, Hiroshi ^a   Yanagitani, Yoshihiro ^a   Tabuchi, Yoshikatsu ^b   Kumahara, Yuichi ^b   Higaki, Jitsuo ^a   Ogihara, Toshio ^a  

^a OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

^b Sakuragaoka Hospital   (Japan)

Author keywords

Angiotensin converting enzyme; Gene polymorphism; Insulin resistance; Postprandial hyperglycaemia

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE; GLUCOSE; INSULIN;

ADULT; ARTICLE; CARDIOVASCULAR DISEASE; CONTROLLED STUDY; DIABETES MELLITUS; GENE DELETION; GENE INSERTION; GENETIC POLYMORPHISM; GENOTYPE; GLUCOSE BLOOD LEVEL; HUMAN; HYPERGLYCEMIA; INSULIN RESISTANCE; MAJOR CLINICAL STUDY; MALE; ORAL GLUCOSE TOLERANCE TEST;

ADULT; DNA; FEMALE; GENOTYPE; GLUCOSE TOLERANCE TEST; HUMANS; HYPERGLYCEMIA; MALE; MIDDLE AGED; PEPTIDYL-DIPEPTIDASE A; POLYMORPHISM, GENETIC; POSTPRANDIAL PERIOD; SEQUENCE DELETION;

EID: 0034126727     PISSN: 03051870     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1681.2000.03278.x     Document Type: Article

References (49)

1. 1. Kawamori R. Asymptomatic hyperglycaemia and early atherosclerotic changes. Diabetes Res. Clin. Pract. 1998; 40 (Suppl.): S35-42.
2. 2. DeFronzo RA, Bonadonna RC, Ferrannini E. Pathogenesis of NIDDM. A balanced overview. Diabetes Care 1992; 15: 318-68.
3. 3. Lorenzi M. Glucose toxicity in the vascular complications of diabetes: The cellular perspective. Diabetes Metab. Rev. 1992; 8: 85-103.
4. 4. Rauen U, Noll T, Piper HM, Lauchart W, Becker HD, De Groot H. Endothelial cell toxicity of preservation solutions: Comparison of endothelial cells of different origin and dependence on growth state. Cryobiology 1994; 31: 144-53.
5. 5. Williams B. Glucose-induced vascular smooth muscle dysfunction: The role of protein kinase C. J. Hypertens. 1995; 13: 477-86.
6. 6. Reaven GM. Role of insulin resistance in human disease (syndrome X): An expanded definition. Annu. Rev. Med. 1993; 44: 121-31.
7. 7. Kaplan NM. The deadly quartet. Upper-body obesity, glucose intolerance, hypertriglyceridemia, and hypertension. Arch. Intern. Med. 1989; 149: 1514-20.
8. 8. Matsuzawa Y, Shimomura I, Nakamura T, Keno Y, Tokunaga K. Pathophysiology and pathogenesis of visceral fat obesity. Ann. N.Y. Acad. Sci. 1993; 676: 270-8.
9. 9. Jauch KW, Hartl W, Guenther B, Wicklmayr M, Rett K, Dietze G. Captopril enhances insulin responsiveness of forearm muscle tissue in non-insulin-dependent diabetes mellitus. Eur. J. Clin. Invest. 1987; 17: 448-54.
10. 10. Pollare T, Lithell H, Berne C. A comparison of the effects of hydrochlorothiazide and captopril on glucose and lipid metabolism in patients with hypertension. N. Engl. J. Med. 1989; 321: 868-73.
11. 11. Allemann Y, Baumann S, Jost M et al. Insulin sensitivity in normotensive subjects during angiotensin converting enzyme inhibition with fosinopril. Eur. J. Clin. Pharmacol. 1992; 42: 275-80.
12. 12. Hansson L, Lindholm LH, Niskanen L et al. Effect of angiotensin-converting-enzyme inhibition compared with conventional therapy on cardiovascular morbidity and mortality in hypertension: The Captopril Prevention Project (CAPPP) randomised trial. Lancet 1999; 353: 611-16.
13. 13. Nakata Y, Katsuya T, Rakugi H et al. Polymorphism of the apolipoprotein E and angiotensin-converting enzyme genes in Japanese subjects with silent myocardial ischemia. Hypertension 1996; 27: 1205-9.
14. 14. Lieberman J, Nosal A, Schlessner A, Sastre Foken A. Serum angiotensin-converting enzyme for diagnosis and therapeutic evaluation of sarcoidosis. Am. Rev. Respir. Dis. 1979; 120: 329-35.
15. 15. Lieberman J, Sastre A. Serum angiotensin-converting enzyme: Elevations in diabetes mellitus. Ann. Intern. Med. 1980; 93: 825-6.
16. 16. Letizia C, Repossi P, Sellini M et al. Serum angiotensin converting enzyme in diabetic retinopathy. Int. J. Tissue React. 1992; 14: 299-305.
17. 17. Migdalis IN, Iliopoulou V, Kalogeropoulou K, Koutoulidis K, Samartzis M. Elevated serum levels of angiotensin-converting enzyme in patients with diabetic retinopathy. South. Med. J. 1990; 83: 425-7.
18. 18. Ninomiya Y, Arakawa M. Serum angiotensin converting enzyme activity in type 2 (non-insulin-dependent) diabetic patients with chronic glomerulonephritis. Diabetes Res. 1989; 11: 121-4.
19. 19. Feman SS, Mericle RA, Reed GW, May JM, Workman RJ. Serum angiotensin converting enzyme in diabetic patients. Am. J. Med. Sci. 1993; 305: 280-4.
20. 20. Tiret L, Rigat B, Visvikis S et al. Evidence, from combined segregation and linkage analysis, that a variant of the angiotensin I-converting enzyme (ACE) gene controls plasma ACE levels. Am. J. Hum. Genet. 1992; 51: 197-205.
21. 21. Schunkert H, Hense HW, Holmer SR et al. Association between a deletion polymorphism of the angiotensin-converting-enzyme gene and left ventricular hypertrophy. N. Engl. J. Med. 1994; 330: 1634-8.
22. 22. Cambien F, Poirier O, Lecerf L et al. Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction. Nature 1992; 359: 641-4.
23. 23. Fujisawa T, Ikegami H, Shen GQ et al. Angiotensin I-converting enzyme gene polymorphism is associated with myocardial infarction, but not with retinopathy or nephropathy, in NIDDM. Diabetes Care 1995; 18: 983-5.
24. 24. Kamitani A, Rakugi H, Higaki J el al. Enhanced predictability of myocardial infarction in Japanese by combined genotype analysis. Hypertension 1995; 25: 950-3.
25. 25. Ohishi M. Fujii K, Minamino T et al. A potent genetic risk factor for restenosis. Nature Genet. 1993; 5: 324-5.
26. 26. Amant C, Bauters C, Bodart JC et al. D allele of the angiotensin I-converting enzyme is a major risk factor for restenosis after coronary stenting. Circulation 1997; 96: 56-60.
27. 27. Ohishi M, Rakugi H, Ogihara T. Association between a deletion polymorphism of the angiotensin-converting-enzyme gene and left ventricular hypertrophy. N. Engl. J. Med. 1994; 331: 1097-8.
28. 28. Hamon M, Bauters C, Amant C et al. Relation between the deletion polymorphism of the angiotensin-converting enzyme gene and late luminal narrowing after coronary angioplasty. Circulation 1995; 92: 296-9.
29. 29. Samani NJ, Martin DS, Brack M et al. Insertion/deletion polymorphism in the angiotensin-converting enzyme gene and risk of restenosis after coronary angioplasty. Lancet 1995; 345: 1013-16.
30. 30. Katsuya T, Koike G, Yee TW et al. Association of angiotensinogen gene T235 variant with increased risk of coronary heart disease. Lancet 1995; 345: 1600-3.
31. 31. Lindpaintner K, Pfeffer MA, Kreutz R et al. A prospective evaluation of an angiotensin-converting-enzyme gene polymorphism and the risk of ischemic heart disease. N. Engl. J. Med. 1995; 332: 706-11.
32. 32. Lindpaintner K, Lee M, Larson MG et al. Absence of association or genetic linkage between the angiotensin-converting-enzyme gene and left ventricular mass. N. Engl. J. Med. 1996; 334: 1023-8.
33. 33. Katsuja T, Horiuchi M, Chen YD et al. Relations between deletion polymorphism of the angiotensin-converting enzyme gene and insulin resistance, glucose intolerance, hyperinsulinemia, and dyslipidemia. Arterioscler. Thromb. Vasc. Biol. 1995; 15: 779-82.
34. 34. Chiu KC, McCarthy JE. The insertion allele at the angiotensin I-converting enzyme gene locus is associated with insulin resistance. Metabolism 1997; 46: 395-9.
35. 35. Huang XH, Rantalaiho V, Wirta O et al. Relationship of the angiotensin-converting enzyme gene polymorphism to glucose intolerance, insulin resistance, and hypertension in NIDDM. Hum. Genet. 1998; 102: 372-8.
36. 36. Jeng JR, Shieh SM, Harn HJ, Lee MM, Sheu WH, Jeng CY. Angiotensin I converting enzyme gene polymorphism and insulin resistance in patients with hypertension. J. Hypertens. 1997; 15: 963-8.
37. 37. World Health Organization Study Group. Diabetes Mellitus. Technical Report Series I. WHO, Geneva. 1985.
38. 38. Panahloo A, Andres C, Mohamed Ali V et al. The insertion allele of the ACE gene I/D polymorphism. A candidate gene for insulin resistance? Circulation 1995; 92: 3390-3.
39. 39. Levy J, Atkinson AB, Bell PM, McCance DR, Hadden DR. Beta-cell deterioration determines the onset and rate of progression of secondary dietary failure in type 2 diabetes mellitus: The 10-year follow-up of the Belfast Diet Study. Diabetes Med. 1998; 15: 290-6.
40. 40. Levy JC, Matthews DR, Hermans MP. Correct homeostasis model assessment (HOMA) evaluation uses the computer program. Diabetes Care 1998; 21: 2191-2.
41. 41. Ito C, Maeda R, Nakamura K, Sasaki H. Prediction of diabetes mellitus (NIDDM). Diabetes Res. Clin. Pract. 1996; 34 (Suppl.): S7-11.
42. 42. Martin B, Warram J, Krolewski A, Bergman R, Soeldner J, Kahn C. Role of glucose and insulin resistance in development of type 2 diabetes mellitus: Results of a 25-year follow-up study. Lancet 1992; 340: 925-9.
43. 43. Cabezas Cerrato J, Garcia Estevez DA, Araujo D, Iglesias M. Insulin sensitivity, glucose effectiveness, and beta-cell function in obese males with essential hypertension: Investigation of the effects of treatment with a calcium channel blocker (diltiazem) or an angiotensin-converting enzyme inhibitor (quinapril). Metabolism 1997; 46: 173-8.
44. 44. Berne C, Pollare T, Lithell H. Effects of antihypertensive treatment on insulin sensitivity with special reference to ACE inhibitors. Diabetes Care 1991; 4: 39-47.
45. 45. Iimura O, Shimamoto K, Matsuda K et al. Effects of angiotensin receptor antagonist and angiotensin converting enzyme inhibitor on insulin sensitivity in fructose-fed hypertensive rats and essential hypertensives. Am. J. Hypertens. 1995; 8: 353-7.
46. 46. Natarajan R, Gonzales N, Xu L, Nadler JL. Vascular smooth muscle cells exhibit increased growth in response to elevated glucose. Biochem. Biophys. Res. Commun. 1992; 187: 552-60.
47. 47. Natarajan R, Gu JL, Rossi J et al. Elevated glucose and angiotensin II increase 12-lipoxygenase activity and expression in porcine aortic smooth muscle cells. Proc. Natl Acad. Sci. USA 1993; 90: 4947-51.
48. 48. Yasunari K, Kohno M, Kano H, Yokokawa K, Horio T, Yoshikawa J. Possible involvement of phospholipase D and protein kinase C in vascular growth induced by elevated glucose concentration. Hypertension 1996; 28: 159-68.
49. 49. Costerousse O, Allegrini J, Lopez M, Alhenc Gelas F. Angiotensin I-converting enzyme in human circulating mononuclear cells: Genetic polymorphism of expression in T-lymphocytes. Biochem. J. 1993; 290: 33-40.