Interference by glycolic acid in the beckman synchron method for lactate: A useful clue for unsuspected ethylene glycol intoxication

Clinical Chemistry

Volumn 46, Issue 6, 2000, Pages 874-875

  Porter, William H ^a   Crellin, Margaret ^a   Rutter, Philip W ^a   Oeltgen, Peter ^a,b  

^a UNIVERSITY OF KENTUCKY MEDICAL CENTER   (United States)

^b LEXINGTON VA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOLIC ACID;

ANALYTIC METHOD; AQUEOUS SOLUTION; ARTICLE; DRUG MONITORING; GAS CHROMATOGRAPHY; LABORATORY TEST; METABOLIC ACIDOSIS; STEADY STATE;

EID: 0034124103     PISSN: 00099147     EISSN: None     Source Type: Journal    
DOI: 10.1093/clinchem/46.6.874     Document Type: Article

References (6)

1. 1. Jacobsen D, Ovrebo S, Ostborg J, Sejersted OM. Glycolate causes the acidosis in ethylene glycol poisoning and is effectively removed by hemodialysis. Acta Med Scand 1984;216:409-16.
2. 2. Gabow PA, Clay K, Sullivan JB, Lepoff R. Organic acids in ethylene glycol intoxication. Ann Intern Med 1986;105:16-20.
3. 3. Hewlett TP, McMartin KE. Ethylene glycol poisoning. The value of glycolic acid determinations for diagnosis and treatment. Clin Toxicol 1986;24: 389-402.
4. 4. Yao HH, Porter WH. Simultaneous determination of ethylene glycol and its major toxic metabolite, glycolic acid, in serum by gas chromatography. Clin Chem 1996;42:292-7.
5. 5. Porter WH, Rutter PW, Yao HH. Simultaneous determination of ethylene glycol and glycolic acid in serum by gas chromatography-mass spectrometry. J Anal Toxicol 1999;23:591-7.
6. 6. Kasidas GP, Rose GA. A new enzymatic method for the determination of glycollate in urine and plasma. Clin Chim Acta 1979;96:25-36.