Phosphorelay as the sole physiological route of signal transmission by the Arc two-component system of Escherichia coli

Journal of Bacteriology

Volumn 182, Issue 13, 2000, Pages 3858-3862

  Kwon, Ohsuk ^a   Georgellis, Dimitris ^a   Lin, E C C ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; ESCHERICHIA COLI; GENE EXPRESSION REGULATION; GENE MUTATION; MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; SIGNAL TRANSDUCTION;

BACTERIAL OUTER MEMBRANE PROTEINS; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; HISTIDINE; MEMBRANE PROTEINS; PHOSPHORYLATION; PROTEIN KINASES; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION;

EID: 0034123699     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/JB.182.13.3858-3862.2000     Document Type: Article

References (30)

1. Arico, B., J. F. Miller, C. Roy, S. Stibitz, D. Monack, S. Falkow, R. Gross, and R. Rappuuli. 1989. Sequences required for expression of Bordetella pertussis virulence factors share homology with prokaryotic signal transduction proteins. Proc. Natl. Acad. Sci. USA 86:6671-6675.
2. Barany, F. 1985. Single-stranded hexameric linkers: a system for in-phase insertion mutagenesis and protein engineering. Gene 37:111-123.
3. Cotter, P. A., S. B. Melville, J. A. Albrecht, and R. P. Gunsalus. 1997. Aerobic regulation of cytochrome d oxidase (cydAB) operon expression in Escherichia coli: roles of Fnr and ArcA in repression and activation. Mol. Microbiol. 25:605-615.
4. Dong, J.-M., J. S. Taylor, D. J. Latour, S. Iuchi, and E. C. C. Lin. 1993. Three overlapping lct genes involved in L-lactate utilization by Escherichia coli. J. Bacteriol. 175:6671-6678.
5. Fu, H.-A., S. Iuchi, and E. C. C. Lin. 1991. The requirement of ArcA and Fnr for peak expression of the cyd operon in Escherichia coli under microaerobic conditions. Mol. Gen. Genet. 226:209-213.
6. Georgellis, D., O. Kwon, and E. C. C. Lin. 1999. Amplification of signaling activity of the Arc two-component system of Escherichia coli by anaerobic metabolites: an in vitro study with different protein modules. J. Biol. Chem. 274:35950-35954.
7. Georgellis, D., O. Kwon, P. De Wulf, and E. C. C. Lin. 1998. Signal decay through a reverse phosphorelay in the Arc two-component signal transduction system. J. Biol. Chem. 273:32864-32869.
8. Georgellis, D., A. S. Lynch, and E. C. C. Lin. 1997. In vitro phosphorylation study of the Arc two-component signal transduction system of Escherichia coli. J. Bacteriol. 179:5429-5435.
9. Hrabak, E. M., and D. K. Willis. 1992. The lemA gene required for pathogenicity of Pseudomonas syringae pv. syringae on bean is a member of a family of two-component regulators. J. Bacteriol. 174:3011-3020.
10. Ishige, K., S. Nagasawa, S.-I. Tokishita, and T. Mizuno. 1994. A novel device of bacterial signal transducers. EMBO J. 13:5195-5202.
11. Iuchi, S. 1993. Phosphorylation/dephosphorylation of the receiver module at the conserved aspartate residue controls transphosphorylation activity of histidine kinase in sensor protein ArcB of Escherichia coli. J. Biol. Chem. 263:23972-23980.
12. Iuchi, S., and E. C. C. Lin. 1988. arcA (dye), a global regulatory gene in Escherichia coli mediating repression of enzymes in aerobic pathways. Proc. Natl. Acad. Sci. USA 85:1888-1892.
13. Iuchi, S., and E. C. C. Lin. 1992. Mutational analysis of signal transduction by ArcB: a membrane sensor protein for anaerobic expression of operons involved in the central aerobic pathways in Escherichia coli. J. Bacteriol. 174:3972-3980.
14. Jourlin, C., M. Ansaldi, and V. Méjean. 1997. Transphosphorylation of the TorR response regulator requires the three phosphorylation sites of the TorS sensor in Escherichia coli. J. Mol. Biol. 267:770-777.
15. Kato, M., T. Mizuno, T. Shimizu, and T. Hakoshima. 1997. Insights into multistep phosphorelay from the crystal structure of the C-terminal HPt domain of ArcB. Cell 88:717-723.
16. Kwon, O., D. Georgellis, A. S. Lynch, D. Boyd, and E. C. C. Lin. 2000. The ArcB sensor kinase of Escherichia coli: genetic exploration of the transmembrane region. J. Bacteriol. 182:2960-2966.
17. Lynch, A. S., and E. C. C. Lin. 1996. Responses to molecular oxygen, p. 1526-1538. In F. C. Neidhardt, R. Curtiss III, J. L. Ingraham, E. C. C. Lin, K. B. Low, B. Magasanik, W. S. Reznikoff, M. Riley, M. Schaechter, and H. E. Umbarger (ed.), Escherichia coli and Salmonella: cellular and molecular biology, 2nd ed. American Society for Microbiology, Washington, D.C.
18. Lynch, A. S., and E. C. C. Lin. 1996. Transcriptional control mediated by the ArcA two-component response regulator protein of Escherichia coli: characterization of DNA binding at target promoters. J. Bacteriol. 178:6238-6249.
19. Matsushika, A., and T. Mizuno. 1998. A dual-signalling mechanism mediated by the ArcB hybrid sensor kinase containing the histidine-containing phosphotransfer domain in Escherichia coli. J. Bacteriol. 180:3973-3977.
20. Miller, J. H. 1972. Experiments in molecular genetics, p. 352-355. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
21. Nagasawa, S., S. Tokishita, H. Aiba, and T. Mizuno. 1992. A novel sensor-regulator protein that belongs to the homologous family of signal-transduction proteins involved in adaptive responses in Escherichia coli. Mol. Microbiol. 6:799-807.
22. Oden, K. L., L. C. Deveaux, C. R. Vibat, J. E. Cronan, Jr., and R. B. Gennis. 1990. Genomic replacement in Escherichia coli K-12 using covalently closed circular plasmid DNA. Gene 30:29-36.
23. Parkinson, J. S., and E. C. Kofoid. 1992. Communication modules in bacterial signaling proteins. Annu. Rev. Genet. 26:71-112.
24. Simons, R. W., F. Houman, and N. Kleckner. 1987. Improved single and multicopy lac-based cloning vectors for protein and operon fusions. Gene 53:85-96.
25. Stevens, A. M., J. M. Sanders, N. B. Shoemaker, and A. A. Salyers. 1992. Genes involved in production of plasmid-like forms by a Bacteroides conjugal chromosomal element share amino acid homology with two-component regulatory systems. J. Bacteriol. 174:2935-2942.
26. Taylor, B. L., and I. B. Zhulin. 1999. PAS domains: internal sensors of oxygen, redox potential, and light. Microbiol. Mol. Biol. Rev. 63:479-506.
27. Tsuzuki, M., K. Ishege, and T. Mizuno. 1995. Phosphotransfer circuitry of the putative multi-signal transducer, ArcB, of Escherichia coli: in vitro studies with mutants. Mol. Microbiol. 18:953-962.
28. Uhl, M. A., and J. F. Miller. 1996. Integration of multiple domains in a two-component sensor protein: the Bordetella pertussis BvgAS phosphorelay. EMBO J. 15:1028-1036.
29. Utsumi, R., S. Katayama, M. Taniguchi, T. Horie, M. Ikeda, S. Igaki, H. Nakagawa, A. Miwa, H. Tanabe, and M. Noda. 1994. Newly identified genes involved in the signal transduction of Escherichia coli K-12. Gene 140:73-77.
30. Way, J. C., M. A. Davis, D. Morisato, D. E. Roberts, and N. Kleckner. 1984. New Tn10 derivatives for transposon mutagenesis and for construction of lacZ operon fusion by transposition. Gene 32:369-379.