An evaluation of the biologic activity and vitamin D receptor binding affinity of the photoisomers of vitamin D3 and previtamin D3

Journal of Nutritional Biochemistry

Volumn 11, Issue 5, 2000, Pages 267-272

  Chen, Tai C ^a   Persons, Kelly S ^a   Lu, Zhiren ^a   Mathieu, Jeffrey S ^a   Holick, Michael F ^a  

^a BOSTON UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Antiproliferation; Keratinocytes; Skin; Thymidine incorporation

Indexed keywords

7 DEHYDROCHOLESTEROL; COLECALCIFEROL; COLECALCIFEROL DERIVATIVE; THYMIDINE; VITAMIN D RECEPTOR;

ARTICLE; BINDING AFFINITY; CELL PROLIFERATION; CONTROLLED STUDY; DNA SYNTHESIS; DRUG ACTIVITY; HUMAN; HUMAN CELL; ISOMER; KERATINOCYTE; SKIN;

CALCITRIOL; CELLS, CULTURED; CHOLECALCIFEROL; DEHYDROCHOLESTEROLS; DNA; DOSE-RESPONSE RELATIONSHIP, DRUG; ERGOSTEROL; HUMANS; ISOMERISM; KERATINOCYTES; PHOTOBIOLOGY; RECEPTORS, CALCITRIOL; SUNLIGHT; THYMIDINE; ULTRAVIOLET RAYS;

EID: 0034123524     PISSN: 09552863     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0955-2863(00)00077-2     Document Type: Article

References (22)

1. Holick M.F. McCollum Award Lecture Vitamin D - new horizons for the 21st century. Am. J. Clin. Nutr. 60:1994;619-630.
2. 3 in human skin. J. Biol. Chem. 268:1993;14888-14892.
3. 3. Endocrinology. 113:1983;1950-1957.
4. 3 on the morphologic and biochemical differentiation of cultured human epidermal keratinocytes grown in serum-free conditions. J. Invest. Dermatol. 86:1986;709-714.
5. 3. J. Cell. Physiol. 146:1991;94-100.
6. 3 photosynthesis in human Skin pigment is not an essential regulator. Science. 211:1981;590-593.
7. 3 by causing its photodegradation. J. Clin. Endocrinol. Metab. 68:1989;882-887.
8. Holick M.F., Garabedian M., DeLuca H.F. 5,6-Trans isomers of cholecalciferol and 25-hydroxycholecalciferol. Substitutes for 1,25-dihydroxycholecalciferol in anephric animals. Biochemistry. 11:1972;2715-2719.
9. Rheinwald J.G., Green H. Serial cultivation of strains of human epidermal keratinocytes The formation of keratinizing colonies from single cells. Cell. 6:1975;331-344.
10. 3 are potentiated by epidermal growth factor and attenuated by insulin in cultured human keratinocytes. J. Invest. Dermatol. 104:1995;113-117.
11. Reinhardt T.A., Horst R.L., Orf J.W., Hollis B.W. A microassay for 1,25-dihydroxyvitamin D not requiring high performance liquid chromatography Application to clinical studies. J. Clin. Endocrinol. Metab. 58:1984;91-98.
12. Chen T.C., Turner A.K., Holick M.F. A method for the determination of the circulating concentration of 1,25-dihydroxyvitamin D. J. Nutr. Biochem. 1:1990;320-327.
13. 3. Biochemistry. 25:1986;1545-1548.
14. 3. Vitamin D: Chemistry, biology and clinical applications of the steroid hormone. (A.W. Norman, R. Bouillon, and M. Thomasset, eds.) Proceedings of the 10th Workshop on Vitamin D. (Strasbourg, France, May 24-29, 1997), pp. 581-582, University of California, Riverside, CA USA.
15. 3. Vitamin D: Chemistry, biology and clinical applications of the steroid hormone. (A.W. Norman, R. Bouillon, and M. Thomasset, eds.) Proceedings of the 10th Workshop on Vitamin D. (Strasbourg, France, May 24-29, 1997), pp. 583-584, University of California, Riverside, CA USA.
16. 3 modulate the hormone-induced increments in osteocalcin gene transcription in osteoblast-like cells. J. Cell. Biochem. 50:1992;124-129.
17. 3. Endocrinology. 115:1981;1476-1483.
18. 3 (as a 6-s-cis analog) stimulates nongenomic but not genomic biological responses. J. Biol. Chem. 268:1993;13811-13819.
19. Hansen, C.M., Mathiasen, I.S., and Binderup, L. (1995). The anti-proliferative and the differentiation inducing effect of vitamin D analogues is not determined by the binding affinity for the vitamin D receptor alone. Clinical Oriented Symposium on Vitamin D: Actions and Application in Dermatology, European Society of Dermatological Research, April 27-29, 1995, Copenhagen, Denmark.
20. Qaw F., Calverley M.J., Schroeder N.J., Trafford D.J.H., Makin H.L.J., Jones G. In vivo metabolism of the vitamin D analog, dihydrotachysterol Evidence for formation of 1α,25-and 1β,25-dihydroxy-dihydrotachysterol metabolites and studies of their biological activity. J. Biol. Chem. 268:1993;282-292.
21. Goeckerman W.H. The treatment of psoriasis. Northwest Med. 24:1925;229.
22. Gonzalez E., Parrish J.A. Ultraviolet phototherapy. Roenigk J.J. Jr, Maibach H.I. Psoriasis. 2nd ed. 1991;519-532 Marcel Dekker, Inc, New York, NY, USA.