A comparative pharmaco-clinic study of ceftriaxone after subcutaneous and intravenous administration in the elderly;Etude pharmaco-clinique comparative de la ceftriaxone par voie sous-cutanee et intraveineuse chez la personne agee

Revue de Geriatrie

Volumn 25, Issue 5, 2000, Pages 337-347

  Melin Coviaux, F ^a   Hary, L ^b   Hurtel, A S ^b   Andrejak, M ^b   Grumbach, Y ^a  

^a AMIENS UNIVERSITY HOSPITAL   (France)

^b NONE

Author keywords

Antibacterial agents; Ceftriaxone; Lower respiratory tract infection; Pharmacokinetics Subcutaneous route; The elderly

Indexed keywords

CEFTRIAXONE;

AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG CLEARANCE; DRUG EFFICACY; DRUG SAFETY; ELDERLY CARE; HUMAN; LOWER RESPIRATORY TRACT INFECTION;

EID: 0034123481     PISSN: 03977927     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (29)

1. - FEIN A. M., NIEDERMAN M S. Severe pneumonia in the elderly Clinics in geriatric Medicine, Féu 1994 , 10, 1 : 121-143.
2. - WOODHEAD M A., MAC FARLANE J T , MC CRACKEN J.S , ROSE D H, FINCH R., Prospective study of the aetiology and outcome of pneumonia in the community Lancet i 1987 ; 671-4.
3. - VENKATESAN P., GLADMAN J., Mc FARLANE J , BARER D , BERMAN P, KINNEAR W , FINCH R. A hospital study of community acquired pneumonia in the elderly Thorax 1990 ; 45 : 254-8.
4. - BRANCATI F.L., CHOW J.W , WAGENER M.M., VACARELLO S. J, YU V.L., Is pneumonia really the old man's friend ? Two years prognosis after community - acquired pneumonia Lancet 1993 . 342 : 30-33.
5. - FINE M.J., SINGER D.E , HANUSA B.H., LAVE J.R., KAPOOR W.N.: Validation of a pneumonia prognostic index using the medisgroups comparative hospital database Am. J Med. 1993 ; 94 . 153-159
6. - DESLANDES D., MOUUAS R. Prévention des infections respiratoires du sujet âgé Gaz Médi 1991 . 98, 29 45-48
7. - HARKNESS G.A , BENTLEY D W., ROGHMANN K.J: Risk factors for nosocomial pneumonia in the elderly Am. J Med 1990 , 89 . 457-63.
8. - MOULIAS R , MEAUME S . SALVATORE R., FAUCHER-CHABERT N., LESOURD B.: Immunité, nutrition et infection respiratoire chez le sujet âgé. Méd. et Hyg 1993 , 51 . 2498-2502
9. - SALMON D , LEPORT C . VILDE J.L.: Facteurs de sensibilité à l'infection et immunité chez le sujet âgé. Méd. Mal Inf 1988 , 18 : 311-317
10. - NORMAND D. C., TOLEDO S D : Infections in elderly persons. An altered clinical presentation. Clinics in geriatric medicine 1992 , 8,4 : 713-719
11. - FINKELSTEIN M , PET KUN W , FREEDMAN M , ANTOPOL S.: Pneumoccocal bacteremia in adults : age - dependant differences in presentation and in outcome. J. Am. Geriat Soc 1983 , 31 19-27
12. - HARPER C., NEWTON P.: Clinical aspects of pneumonia in the elderly veteran. J Am. Geriat Soc. 1989 ; 37 867-872.
13. - BERNARDAC P., HENNQUIN L , THOLLOT F.: Poumon du 3ème âge Editions techniques. Encycl Med Chir (Paris-France) 1991 , radiodiagnostic III : 324-980.
14. - MURPHY T F., FINE B C . Bacteremic pneumococcal pneumonia in the elderly. Am J Med. Sci 1984 , 288 . 114-118
15. - SIMS RV., STEINMAN WC., McCONVILLE JH., KING LR , ZWICK WC, SANFORD SCHWARTZ J.: The clinical effectiveness of pneumococcal vaccine in the elderly Ann. Intern. Med 1988 , 108,5 653-657.
16. - PARKER BM, CUSACK BJ, VESTAL RE . Pharmacokinetic Optimisation of Drug Therapy in Elderly Patients Drugs & Aging. 1995 , 7 : 10-18.
17. - STOECKEL K., Mc NAMARA P J., BRANDT R , PLOZZA-NOT-TEBROCK H , ZIEGLET W. H : Effects of concentration dependant plasma protein binding on ceftriaxone kinetics Clin. Pharmacol. Therap 1981 , 29 . 650-6
18. - PATEL I.H., KAPLAN S.A . Pharmacokinetic profile of ceftriaxone in man. The American J.of Med 1984 ; October 19 : 17-25
19. - LEBEL M., GREGOIRE S., CARON M , BERGERON M. G : Difference in blister fluid penetration after single and multiple doses of ceftriaxone. Chemotherapy 1985 ; 28,1 : 123-7
20. - ARDVISSON A., ALVAN G., ANVELIN B., BORGA O.: Ceftriaxone renal and biliary excretion and effect on colon microfloral J Antimicrob Chemother 1982 ; 10 : 207-215.
21. - DUCROIX J.P., GUERLIN M , HARY L., SMAIL A., DENAMURE E,. EB F.. ANDREJAK M., BAILLET J.: Etude clinique et pharmacocinétique de la ceftriaxone dans le traitement de quatorze épisodes d'infection du liquide d'ascite. Path. Biol. 1988 ; 36,8 . 1007-1010.
22. - LUDERER J. R., PATEL I H., DURKIN J , SCHNEK D. W.: Age and ceftriaxone kinetics. Clinical pharmacology and therapeutic 1984 ; 35,1 : 19-25.
23. - BERGAN T., Pharmacokinetics of tissue penetration of antibiotics Rev. Inf. Dis. 1981 ; 3 : 45-46
24. - BORNER K , LODE H . HAMPLE B , PFEUFFER M., KOEPPE P Comparative pharmacokinetics of ceftriaxone after subcutaneous and intravenous administration Chemotherapy 1985 ; 31 : 237-45.
25. - BRICAIRE F., CASTAING J L., POCIDALO J J., VILDE J L : Study of the pharmacokinetics and tolerance of ceftriaxone after subcutaneous administration Path. Biol 1988 ; 36, 5 bis : 702-705.
26. - TRAUTMANN KH, HAEFELFINGER P. (1981).: Determination of Ro13-9904 in plasma, urine and bile by means of ion-pair reversed phase chromatography. J High Chromatogr Commun 4 : 54-59.
27. - CHOW SC AND LIU JP : Design and analysis of Bioavailability and Bioequivalence studies. New York Marcel DEKKER Inc 1992.
28. - VEYSSIER P , MONTAGNE V., DARCHIS J. P, KALOUSTIAN E., LOKIEC : Etude pharmacocinétique de la ceftriaxone chez le sujet âgé après administration intraveineuse. Acta. Therapeutica 1987 ; 13,4 : 395-405
29. - HAYTON W. L. ; STOECKEL K. Age-associated changes in ceftriaxone pharmacokinetics Clinical pharmacokinetic 1986 ; 11 : 76-86.