Lamellar body formation in normal and surfactant protein B-deficient fetal mice

Laboratory Investigation

Volumn 80, Issue 3, 2000, Pages 395-403

  Stahlman, Mildred T ^a,c   Gray, Mary Phillips ^a   Falconieri, Mary W ^b   Whitsett, Jeffrey A ^b   Weaver, Timothy E ^b  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^c VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SURFACTANT PROTEIN B;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; CONTROLLED STUDY; EMBRYO; FETUS; FETUS LUNG; GENOTYPE; LAMELLAR BODY; LUNG ALVEOLUS EPITHELIUM; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN PROCESSING; RESPIRATORY DISTRESS;

EID: 0034122943     PISSN: 00236837     EISSN: None     Source Type: Journal    
DOI: 10.1038/labinvest.3780044     Document Type: Article

References (21)

1. Breslin JS and Weaver TE (1992). Binding, uptake, and localization of surfactant protein B in isolated rat alveolar type II cells. Am J Physiol 262(6 Pt 1):L699-L707.
2. Chevalier G and Collet AJ (1972). In vivo incorporation of choline-3H, leucine-3H and galactose-3H in alveolar type II pneumocytes in relation to surfactant synthesis: A quantitative radioautographic study in mouse by electron microscopy. Anat Rec 174(3):289-310.
3. Clark JC, Weaver TE, Iwamoto HS, Ikegami M, Jobe AH, Hull WM, and Whitsett JA (1997). Decreased lung compliance and air trapping in heterozygous SP-B-deficient mice. Am J Respir Cell Mol Biol 16:46-52.
4. Clark JC, Wert SE, Bachurski CJ, Stahlman MT, Stripp BR, Weaver TE, and Whitsett JA (1995). Targeted disruption of the surfactant protein B gene disrupts surfactant homeostasis, causing respiratory failure in newborn mice. Proc Natl Acad Sci USA 92(17):7794-7798.
5. Hamvas A, Cole FS, deMello DE, Moxley M, Whitsett JA, Colten HR, and Nogee LM (1994). Surfactant protein B deficiency: Antenatal diagnosis and prospective treatment with surfactant replacement. J Pediatr 125(3):356-361.
6. Henry M, Ikegami M, Ueda T, and Jobe A (1996). Surfactant protein B metabolism in newborn rabbits. Biochim Biophys Acta 1300(2):97-102.
7. Lin S, Na CL, Akinbi HT, Apsley KS, Whitsett JA, and Weaver TE (1999). Surfactant protein B (SP-B) -/-mice are rescued by restoration of SP-B expression in alveolar type II cells but not Clara cells. J Biol Chem 274(27):19168-19174.
8. Lin S, Phillips KS, Wilder MR, and Weaver TE (1996). Structural requirements for intracellular transport of pulmonary surfactant protein B (SP-B). Biochim Biophys Acta 1312(3): 177-185.
9. Luff JH (1961). Improvements in epoxy resin embedding methods. J Biophys Biochem Cytol 9:409-414.
10. Millonig G (1961). Advantages of a phosphate buffer for OsO4 solutions in fixation. J Appl Physics 32:1637.
11. Nogee LM, DeMello DE, Dehner LP, and Colten HR (1993). Brief report: Deficiency of pulmonary surfactant protein B in congenital alveolar proteinosis. N Engl J Med 328(6):406-410.
12. O'Reilly MA, Weaver TE, Pilot-Matias TJ, Sarin VK, Gazdar AF, and Whitsett JA (1989). In vitro translation, posttranslational processing and secretion of pulmonary surfactant protein B precursors. Biochim Biophys Acta 1011:140-148.
13. Ross GF, Ikegami M, Steinhilber W, and Jobe AH (1999). Surfactant protein C in fetal and ventilated preterm rabbit lungs. Am J Physiol 277:L1104-L1108.
14. Takahashi A, Waring AJ, Amirkhanian J, Fan B, and Taeusch HW (1990). Structure-function relationships of bovine pulmonary surfactant proteins: SP-B and SP-C. Biochim Biophys Acta 1044:43-49.
15. Tokieda K, Iwamoto HS, Bachurski C, Wert SE, Hull WM, Ikeda K, and Whitsett JA (1999). Surfactant protein-B deficient mice are susceptible to hyperoxic lung injury. Am J Respir Cell Mol Biol 21:463-472.
16. Voorhout WF, Veenendaal T, Haagsman HP, Weaver TE, Whitsett JA, van Golde LM, and Geuze HJ (1992). Intracellular processing of pulmonary surfactant protein B in an endosomal/lysosomal compartment. Am J Physiol 263(4 Pt 1):L479-L486.
17. Vorbroker DK, Profitt SA, Nogee LM, and Whitsett JA (1995a). Aberrant processing of surfactant protein C (SP-C) in hereditary SP-B deficiency. Am J Physiol: Lung Cell Mol Physiol 268(4 Pt 1):L647-L656.
18. Vorbroker DK, Voorhout WF, Weaver TE, and Whitsett JA (1995b). Posttranslational processing of surfactant protein C in rat type II cells. Am J Physiol 269(6 Pt 1):L727-L733.
19. Wang Z, Hall SB, and Notter RH (1996). Roles of different hydrophobic constituents in the adsorption of pulmonary surfactant. J Lipid Res 37(4):790-798.
20. Weaver TE and Whitsett JA (1989). Processing of hydrophobic pulmonary surfactant protein B in rat type II cells. Am J Physiol 257(2 Pt 1):L100-L108.
21. Yu SH and Possmayer F (1988). Comparative studies on the biophysical activities of the low-molecular-weight hydrophobic proteins purified from bovine pulmonary surfactant. Biochim Biophys Acta 961(3):337-350.