Characterization of an acyclovir-resistant herpes simplex virus type 2 strain isolated from a premature neonate

Journal of Infectious Diseases

Volumn 181, Issue 4, 2000, Pages 1458-1461

  Oram, Ronda J ^a   Marcellino, Daniel ^b   Strauss, Daniel ^b   Gustafson, Erik ^c   Talarico, Christine L ^d   Root, Adrienne K ^d   Sharma, Prem L ^c,e   Thompson, Ken ^a   Fingeroth, Joyce D ^c   Crumpacker, Clyde ^c   Herold, Betsy C ^b  

^a UNIVERSITY OF CHICAGO   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d GLAXOSMITHKLINE   (United States)

^e EMORY UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACICLOVIR;

ARTICLE; CASE REPORT; HERPES; HERPES SIMPLEX VIRUS 2; HUMAN; HUMAN CELL; MALE; NEWBORN; PREMATURITY; PRIORITY JOURNAL; VIRUS ISOLATION; VIRUS REPLICATION;

ACYCLOVIR; ADULT; ANIMALS; ANTIVIRAL AGENTS; CERCOPITHECUS AETHIOPS; CRICETINAE; DRUG RESISTANCE, MICROBIAL; FATAL OUTCOME; FEMALE; HERPESVIRUS 2, HUMAN; HUMANS; INFANT, NEWBORN; MALE; MICE; MUTATION; THYMIDINE KINASE; TUMOR CELLS, CULTURED; VERO CELLS; VIRUS REPLICATION;

EID: 0034122431     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/315387     Document Type: Article

References (15)

1. 1. Christophers J, Clayton J, Craske J, et al. Survey of resistance of herpes simplex virus to acyclovir in northwest England. Antimicrob Agents Chemother 1998; 42:868-72.
2. 2. Rabalais GP, Nusinoff-Lehrman S, Arvin AM, Levin MJ. Antiviral susceptibilities of herpes simplex virus isolates from infants with recurrent mucocutaneous lesions after neonatal infection. Pediatr Infect Dis J 1989; 8: 221-3.
3. 3. Gustafson EA, Chillemi AC, Sage DR, Fingeroth JD. The Epstein-Barr virus thymidine kinase does not phosphorylate ganciclovir or acyclovir and demonstrates a narrow substrate specificity compared to a herpes simplex virus type 1 thymidine kinase. Antimicrob Agents Chemother 1998; 42: 2923-31.
4. 4. Herold BC, Kirkpatrick R, Marcellino D, et al. Bile salts: natural detergents for the prevention of sexually transmitted diseases. Antimicrob Agents Chemother 1999; 43:745-51.
5. 5. Roller RJ, Herold BC. Characterization of a BHK(TK ) cell clone resistant to post-attachment entry by herpes simplex 1 and 2. J Virol 1997; 71:5805-13.
6. 6. Herold BC, Siston A, Bremer J, et al. Sulfated carbohydrate compounds prevent microbial adherence by sexually transmitted disease pathogens. Antimicrob Agents Chemother 1997; 41:2776-80.
7. 7. Stanberry LR, Kit S, Myers MG. Thymidine kinase-deficient herpes simplex virus type 2 genital infection in guinea pigs. J Virol 1985; 55:322-8.
8. 8. Lonsdale DM. A rapid technique for distinguishing herpes-simplex virus type 1 from type 2 by restriction-enzyme technology. Lancet 1979; 1:849-52.
9. 9. Whitley R, Arvin A, Prober C, et al. Predictors of morbidity and mortality in neonates with herpes simplex virus infections. N Engl J Med 1991; 324: 450-4.
10. 10. Kimberlin D, Powell D, Gruber W, et al. Administration of oral acyclovir suppressive therapy after neonatal herpes simplex virus disease limited to the skin, eyes, and mouth: results of a phase I/II trial. Pediatr Infect Dis J 1996; 15:247-54.
11. 11. Nyquist A, Rotbart HA, Cotton M, et al. Acyclovir-resistant neonatal herpes simplex virus infection of the larynx. J Pediatr 1994; 124:967-71.
12. 12. Gaudreau A, Hill E, Balfour HH Jr, Erice A, Boivin G. Phenotypic and genotypic characterization of acyclovir-resistant herpes simplex viruses from immunocompromised patients. J Infect Dis 1998; 178:297-303.
13. 13. Hay KA, Gaydos A, Tenser RB. The role of herpes simplex thymidine kinase expression in neurovirulence and latency in newborn vs. adult mice. J Neuroimmunol 1995; 61:41-52.
14. 14. Suzutani T, Koyano S, Takada M, Yoshida I, Azuma M. Analysis of the relationship between cellular thymidine kinase activity and virulence of thymidine kinase negative herpes simplex virus types 1 and 2. Microbiol Immunol 1995; 39:787-94.
15. 15. Chen SH, Cook WJ, Grove KL, Coen DM. Human thymidine kinase can functionally replace herpes simplex virus type 1 thymidine kinase for viral replication in mouse sensory ganglia and reactivation from latency upon explant. J Virol 1998; 72:6710-5.