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Volumn 100, Issue 2, 2000, Pages 203-208

Efficient induction of an antigen-specific, T helper type 1 immune response by interleukin-12-secreting fibroblasts

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; GAMMA INTERFERON; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G2A; INTERLEUKIN 12; INTERLEUKIN 4; OVALBUMIN; RECOMBINANT INTERLEUKIN 12;

EID: 0034121865     PISSN: 00192805     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2567.2000.00038.x     Document Type: Article
Times cited : (4)

References (32)
  • 1
    • 0025864111 scopus 로고
    • Cytokine secretion phenotypes of TH cells: How many subsets, how much regulation?
    • 1. MOSMANN T.R. (1991) Cytokine secretion phenotypes of TH cells: how many subsets, how much regulation?. Res Immunol 142, 9.
    • (1991) Res Immunol , vol.142 , pp. 9
    • Mosmann, T.R.1
  • 3
  • 5
    • 0031865845 scopus 로고    scopus 로고
    • Intestinal nematode parasites, cytokines and effector mechanisms
    • 5. ELSE K.J. & FINKELMAN F.D. (1998) Intestinal nematode parasites, cytokines and effector mechanisms. Int J Parasitol 28, 1145.
    • (1998) Int J Parasitol , vol.28 , pp. 1145
    • Else, K.J.1    Finkelman, F.D.2
  • 7
    • 0345646403 scopus 로고    scopus 로고
    • The role of helper t cell subsets in autoimmune diseases
    • 7. LAFAILLE J.J. (1998) The role of helper T cell subsets in autoimmune diseases. Cytokine Growth Factor Rev 9, 139.
    • (1998) Cytokine Growth Factor Rev , vol.9 , pp. 139
    • Lafaille, J.J.1
  • 8
    • 0031871705 scopus 로고    scopus 로고
    • A role for Th1 and Th2 cells in the immunopathogenesis of atopic dermatitis
    • 8. GREWE M., BRUUNZEEL-KOOMEN C.A., SCHOPF E. et al. (1998) A role for Th1 and Th2 cells in the immunopathogenesis of atopic dermatitis. Immunol Today 19, 359.
    • (1998) Immunol Today , vol.19 , pp. 359
    • Grewe, M.1    Bruunzeel-Koomen, C.A.2    Schopf, E.3
  • 9
    • 0032033419 scopus 로고    scopus 로고
    • Cytokines induce the development of functionally heterogeneous T helper cell subsets
    • 9. O'GARRA A. (1998) Cytokines induce the development of functionally heterogeneous T helper cell subsets. Immunity 8, 275.
    • (1998) Immunity , vol.8 , pp. 275
    • O'Garra, A.1
  • 10
    • 0031937388 scopus 로고    scopus 로고
    • Proinflammatory and immunoregulatory functions of interleukin-12
    • 10. TRINCHIERI G. (1998) Proinflammatory and immunoregulatory functions of interleukin-12. Int Rev Immunol 16, 365.
    • (1998) Int Rev Immunol , vol.16 , pp. 365
    • Trinchieri, G.1
  • 11
    • 0028231754 scopus 로고
    • Endogenous interleukin-12 (IL-12) regulates granuloma formation induced by eggs of Schistosoma mansoni and exogenous IL-12 both inhibits and prophylactically immunizes against egg pathology
    • 11. WYNN T.A., ELTOU I., OSWALD I.P., CHEEVER A.W. & SHER A. (1994) Endogenous interleukin-12 (IL-12) regulates granuloma formation induced by eggs of Schistosoma mansoni and exogenous IL-12 both inhibits and prophylactically immunizes against egg pathology. J Exp Med 179, 1551.
    • (1994) J Exp Med , vol.179 , pp. 1551
    • Wynn, T.A.1    Eltou, I.2    Oswald, I.P.3    Cheever, A.W.4    Sher, A.5
  • 12
    • 0030790652 scopus 로고    scopus 로고
    • Interleukin 12 (IL-12) is crucial to the development of protective immunity in mice intravenously infected with Mycobacterium tuberculosis
    • 12. COOPER A.M., MAGRAM J., FERRANTE J. & ORME I.M. (1997) Interleukin 12 (IL-12) is crucial to the development of protective immunity in mice intravenously infected with Mycobacterium tuberculosis. J Exp Med 186, 39.
    • (1997) J Exp Med , vol.186 , pp. 39
    • Cooper, A.M.1    Magram, J.2    Ferrante, J.3    Orme, I.M.4
  • 14
    • 0031202698 scopus 로고    scopus 로고
    • In vivo IL-12 administration induces profound by transient commitment to t helper cell type 1-associated patterns of cytokine and antibody production
    • 14. REMPEL J.D., WANG M. & HAYGLASS K.T. (1997) In vivo IL-12 administration induces profound by transient commitment to T helper cell type 1-associated patterns of cytokine and antibody production. J Immunol 159, 1490.
    • (1997) J Immunol , vol.159 , pp. 1490
    • Rempel, J.D.1    Wang, M.2    Hayglass, K.T.3
  • 15
    • 0029946526 scopus 로고    scopus 로고
    • Potential clinical applications of interleukin-12
    • 15. CHOUGNET C. & SHEARER G.M. (1996) Potential clinical applications of interleukin-12. Curr Opin Hematol 3, 216.
    • (1996) Curr Opin Hematol , vol.3 , pp. 216
    • Chougnet, C.1    Shearer, G.M.2
  • 16
    • 0031924595 scopus 로고    scopus 로고
    • Phase I trial of subcutaneous recombinant human interleukin-12 in patients with advanced renal cell carcinoma
    • 16. MOTZER R.J., RAKHIT A., SCHWARTZ L.H. et al. (1998) Phase I trial of subcutaneous recombinant human interleukin-12 in patients with advanced renal cell carcinoma. Clin Cancer Res 4, 1183.
    • (1998) Clin Cancer Res , vol.4 , pp. 1183
    • Motzer, R.J.1    Rakhit, A.2    Schwartz, L.H.3
  • 17
    • 0342636415 scopus 로고
    • Interleukin-2-secreting mouse fibroblasts transfected with genomic DNA from murine melanoma cells prolong the survival of mice with melanoma
    • 17. KIM T.S. & COHEN E.P. (1994) Interleukin-2-secreting mouse fibroblasts transfected with genomic DNA from murine melanoma cells prolong the survival of mice with melanoma. Cancer Res 54, 2531.
    • (1994) Cancer Res , vol.54 , pp. 2531
    • Kim, T.S.1    Cohen, E.P.2
  • 18
    • 0033048720 scopus 로고    scopus 로고
    • Interleukin-12-secreting fibroblasts are more efficient than free recombinant interleukin-12 in inducing the persistent resistance to Mycobacterium avium infection
    • 18. KANG B.Y., CHUNG S.W., LIM Y.S. et al. (1999) Interleukin-12-secreting fibroblasts are more efficient than free recombinant interleukin-12 in inducing the persistent resistance to Mycobacterium avium infection. Immunology 97, 474.
    • (1999) Immunology , vol.97 , pp. 474
    • Kang, B.Y.1    Chung, S.W.2    Lim, Y.S.3
  • 19
    • 0027953555 scopus 로고
    • Fibroblasts genetically engineered to secrete interleukin 12 can suppress tumor growth and induce antitumor immunity to a murine melanoma in vivo
    • 19. TAHARA H., ZEH H.J. III, STORKUS W.J. et al. (1994) Fibroblasts genetically engineered to secrete interleukin 12 can suppress tumor growth and induce antitumor immunity to a murine melanoma in vivo. Cancer Res 54, 182.
    • (1994) Cancer Res , vol.54 , pp. 182
    • Tahara, H.1    Zeh H.J. III2    Storkus, W.J.3
  • 20
    • 0028877056 scopus 로고
    • Heterogeneity of intracellular cytokine synthesis at the single cell level in polarized T helper 1 and helper 2 populations
    • 20. OPENSHAW P., MURPHY E., HOSKEN N.A. et al. (1995) Heterogeneity of intracellular cytokine synthesis at the single cell level in polarized T helper 1 and helper 2 populations. J Exp Med 182, 1357.
    • (1995) J Exp Med , vol.182 , pp. 1357
    • Openshaw, P.1    Murphy, E.2    Hosken, N.A.3
  • 21
    • 0031134912 scopus 로고    scopus 로고
    • An ovalbumin-IL-12 fusion protein is more effective than ovalbumin plus free recombinant IL-12 in inducing a T helper cell type 1-dominated immune response and inhibiting antigen-specific IgE production
    • 21. KIM T.S., DEKYUYFF R.H., RUPPER MAECKER H.T., LEVY S. & UMETSU D.T. (1997) An ovalbumin-IL-12 fusion protein is more effective than ovalbumin plus free recombinant IL-12 in inducing a T helper cell type 1-dominated immune response and inhibiting antigen-specific IgE production. J Immunol 158, 4137.
    • (1997) J Immunol , vol.158 , pp. 4137
    • Kim, T.S.1    Dekyuyff, R.H.2    Rupper Maecker, H.T.3    Levy, S.4    Umetsu, D.T.5
  • 23
    • 0024328379 scopus 로고
    • Different T helper cell subsets elicited in mice utilizing two different adjuvant vehicles: The role of endogenous interleukin 1 in proliferative responses
    • 23. GRUN J.L. & MAURER P.H. (1989) Different T helper cell subsets elicited in mice utilizing two different adjuvant vehicles: the role of endogenous interleukin 1 in proliferative responses. Cell Immunol 121, 134.
    • (1989) Cell Immunol , vol.121 , pp. 134
    • Grun, J.L.1    Maurer, P.H.2
  • 24
    • 0027534132 scopus 로고
    • Allergen-dependent induction of interleukin-4 synthesis in vivo
    • 24. YANG X. & HAYGLASS K.T. (1993) Allergen-dependent induction of interleukin-4 synthesis in vivo. Immunology 78, 74.
    • (1993) Immunology , vol.78 , pp. 74
    • Yang, X.1    Hayglass, K.T.2
  • 25
    • 0029965236 scopus 로고    scopus 로고
    • Reversibility of T helper 1 and 2 populations is lost after long-term stimulation
    • 25. MURPHY E., SHIBUYA K., HOSKEN N. et al. (1996) Reversibility of T helper 1 and 2 populations is lost after long-term stimulation. J Exp Med 183, 901.
    • (1996) J Exp Med , vol.183 , pp. 901
    • Murphy, E.1    Shibuya, K.2    Hosken, N.3
  • 26
    • 0029148905 scopus 로고
    • Cancer immunotherapy of established tumors with IL-12. Effective delivery by genetically engineered fibroblasts
    • 26. ZITVOGEL L., TAHARA H., ROBBINS P.D. et al. (1995) Cancer immunotherapy of established tumors with IL-12. Effective delivery by genetically engineered fibroblasts. J Immunol 155, 1393.
    • (1995) J Immunol , vol.155 , pp. 1393
    • Zitvogel, L.1    Tahara, H.2    Robbins, P.D.3
  • 27
    • 0030854844 scopus 로고    scopus 로고
    • Reduced efficacy of allogeneic versus syngeneic fibroblasts modified to secrete cytokines as a tumor vaccine adjuvant
    • 27. ARUGA A., ARUGA E. & CHANG A.E. (1997) Reduced efficacy of allogeneic versus syngeneic fibroblasts modified to secrete cytokines as a tumor vaccine adjuvant. Cancer Res 57, 3230.
    • (1997) Cancer Res , vol.57 , pp. 3230
    • Aruga, A.1    Aruga, E.2    Chang, A.E.3
  • 28
    • 9844239373 scopus 로고    scopus 로고
    • Interferon-α gene therapy for cancer: Retroviral transduction of fibroblasts and particle-mediated transfection of tumor cells are both effective strategies for gene delivery in murine tumor models
    • 28. TUTING T., GAMBOTTO A., BAAR J. et al. (1997) Interferon-α gene therapy for cancer: retroviral transduction of fibroblasts and particle-mediated transfection of tumor cells are both effective strategies for gene delivery in murine tumor models. Gene Ther 4, 1053.
    • (1997) Gene Ther , vol.4 , pp. 1053
    • Tuting, T.1    Gambotto, A.2    Baar, J.3
  • 29
    • 0032952107 scopus 로고    scopus 로고
    • Adjuvant immunotherapy using fibroblasts genetically engineered to secrete interleukin 12 prevents recurrence after surgical resection of established tumors in a murine adenocarcinoma model
    • 29. MARSUMOTO G., SUNAMURA M., SHIMAMURA H. et al. (1999) Adjuvant immunotherapy using fibroblasts genetically engineered to secrete interleukin 12 prevents recurrence after surgical resection of established tumors in a murine adenocarcinoma model. Surgery 125, 257.
    • (1999) Surgery , vol.125 , pp. 257
    • Marsumoto, G.1    Sunamura, M.2    Shimamura, H.3
  • 30
    • 0032851163 scopus 로고    scopus 로고
    • Interleukin 2 gene therapy of colorectal carcinoma with autologous irradiated tumor cells and genetically engineered fibroblasts: A phase I study
    • 30. SOBOL R.E., SHAWLER D.L., CARSON C. et al. (1999) Interleukin 2 gene therapy of colorectal carcinoma with autologous irradiated tumor cells and genetically engineered fibroblasts: a phase I study. Clin Cancer Res 5, 2359.
    • (1999) Clin Cancer Res , vol.5 , pp. 2359
    • Sobol, R.E.1    Shawler, D.L.2    Carson, C.3
  • 31
    • 0031259706 scopus 로고    scopus 로고
    • Decreased expression of cytokines that induced type 1 helper T cell/interferon-gamma responses in genetically susceptible mice infected with Mycobacterium avium
    • 31. KOBAYASHI K., NAKATA N., KAI M., KASAMA T., HANYUDA Y. & HATANO Y. (1997) Decreased expression of cytokines that induced type 1 helper T cell/interferon-gamma responses in genetically susceptible mice infected with Mycobacterium avium. Clin Immunol Immunopathol 85, 112.
    • (1997) Clin Immunol Immunopathol , vol.85 , pp. 112
    • Kobayashi, K.1    Nakata, N.2    Kai, M.3    Kasama, T.4    Hanyuda, Y.5    Hatano, Y.6
  • 32
    • 0028934155 scopus 로고
    • Switch from a type 2 to a type 1 T helper cell response and cure of established Leishmania major infection in mice is induced by combined therapy with interleukin 12 and Pentostam
    • 32. NABORS G.S., AFONSO L.C.C., FARRELL J.P. & SCOTT P. (1995) Switch from a type 2 to a type 1 T helper cell response and cure of established Leishmania major infection in mice is induced by combined therapy with interleukin 12 and Pentostam. Proc Natl Acad Sci USA 92, 3142.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 3142
    • Nabors, G.S.1    Afonso, L.C.C.2    Farrell, J.P.3    Scott, P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.