Zebrafish no isthmus reveals a role for pax2.1 in tubule differentiation and patterning events in the pronephric primordia

Development

Volumn 127, Issue 10, 2000, Pages 2089-2098

  Majumdar, Arindam ^a   Lun, Klaus ^b   Brand, Michael ^b   Drummond, Iain A ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

no isthmus; noi; pax2.1; Pronephros; Tubulogenesis; wt1; Zebrafish

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); MONOCLONAL ANTIBODY; VASCULOTROPIN;

ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CLOACA; DEVELOPMENTAL GENETICS; EMBRYO; EPITHELIUM; GENE MUTATION; GLOMERULUS; KIDNEY DEVELOPMENT; KIDNEY TUBULE; NEPHRON; NONHUMAN; PODOCYTE; PRIMORDIAL GERM CELL; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE; ZEBRA FISH;

ANIMALS; BODY PATTERNING; DNA-BINDING PROTEINS; KIDNEY GLOMERULUS; KIDNEY TUBULES; MUTAGENESIS; PAX2 TRANSCRIPTION FACTOR; TRANSCRIPTION FACTORS; ZEBRAFISH; ZEBRAFISH PROTEINS;

ANIMALIA; DANIO RERIO; ENTEROBACTER; GLOMERULUS; VERTEBRATA;

EID: 0034121744     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (46)

1. Armstrong, J. F., Pritchard-Jones, K., Bickmore, W. A., Hastie, N. D. and Bard, J. B. (1943). The expression of the Wilms' tumour gene, WT1, in the developing mammalian embryo. Mech. Dev. 40, 85-97.
2. Brand, M., Heisenberg, C. P., Jiang, Y. J., Beuchle, D., Lun, K., Furutani-Seiki, M., Granato, M., Haffter, P., Hammerschmidt, M., Kane, D. A., et al. (1996). Mutations in zebrafish genes affecting the formation of the boundary between midbrain and hindbrain. Development 123, 179-190.
3. Brandli, A. W. (1999). Towards a molecular anatomy of the Xenopus pronephric kidney. Int. J. Dev. Biol. 43, 381-395.
4. Carroll, T. J., Wallingford, J. B. and Vize, P. D. (1994) Dynamic patterns of gene expression in the developing pronephros of Xenopus laevis. Dev. Genet. 24, 199-207.
5. Chamberlin, H. M., Palmer, R. E., Newman, A. P., Sternberg, P. W., Baillie, D. L. and Thomas, J. H. (1997). The PAX gene egl-38 mediates developmental patterning in Caenorhabditis elegans. Development 124, 3919-3928.
6. Dehhi, M., Ghahremani, M., Lechner, M., Dressler, G. and Pelletier, J. (1996). The paired-box transcription factor, PAX2, positively modulates expression of the Wilms' tumor suppressor gene (WT1). Oncogene 13, 447-453.
7. Dent, J. A., Poison, A. G. and Klymkowsky, M. W. (1989). A whole-mount immunocytochemical analysis of the expression of the intermediate filament protein vimentin in Xenopus. Development 105, 61-74.
8. Dorfler, P. and Busslinger, M. (1996). C-terminal activating and inhibitory domains determine the transactivation potential of BSAP (Pax-5). Pax-2 and Pax-8. EMBO J. 15, 1971-1982.
9. Dressler, G. R., Deutsch, U., Chowdhury, K., Nornes, H. O. and Gruss, P. (1990). Pax2, a new murine paired-box-containing gene and its expression in the developing excretory system. Development 109, 787-795.
10. Dressler, G. R., Wilkinson, J. E., Rothenpieler, U. W., Patterson, L. T., Williams-Simons, L. and Westphal, H. (1993). Deregulation of Pax-2 expression in transgenic mice generates severe kidney abnormalities. Nature 362, 65-67.
11. Dressler, G. R. and Woolf, A. S. (1999). Pax2 in development and renal disease. Int J Dev. Biol. 43, 463-468.
12. Driever, W., Solnica-Krezel, L., Schier, A. F., Neuhauss, S. C., Malicki, J., Stemple, D. L., Stainier, D. Y., Zwartkruis, F., Abdelilah, S., Rangini, Z., et al. (1996). A genetic screen for mutations affecting embryogenesis in zebrafish. Development 123, 37-46.
13. Drummond, I. A. (2000). The zebrafish pronephros: a genetic system for studies of kidney development. Pediatr. Nephrol. (in press).
14. Drummond, I. A., Majumdar, A., Hentschel, H., Elger, M., Solnica-Krezel, L., Schier, A. F., Neuhauss, S. C., Stemple, D. L., Zwartkruis, F., Kangini, Z., et al. (1998). Early development of the zebrafish pronephros and analysis of mutations affecting pronephric function. Development 125, 4655-4667.
15. Fu, W. and Noll, M. (1997). The Pax2 homolog sparkling is required for development of cone and pigment cells in the Drosophila eye [see comments]. Genes Dev. 11, 2066-2078.
16. Haffter, P., Granato, M., Brand, M., Mullins, M. C., Hammerschmidt, M., Kane, D. A., Odenthal, J., van Eeden, F. J., Jiang, Y. J., Heisenberg, C. P., et al. (1996). The identification of genes with unique and essential functions in the development of the zebratish. Danio rerio. Development 123, 1-36.
17. Hastie, N. D. (1992). Dominant negative mutations in the Wilms tumour (WT1) gene cause Denys- Drash syndrome-proof that a tumour-suppressor gene plays a crucial role in normal genitourinary development. Hum. Mol. Genet. 1, 293-295.
18. Heller, N. and Brandli, A. W. (1997). Xenopus Pax-2 displays multiple splice forms during embryogenesis and pronephric kidney development. Mech. Dev. 69, 83-104.
19. Humphrey, C. and Pittman, F. (1974). A simple methylene blue-azure II-basic fuchsin stain for epoxy-embedded tissue sections. Stain Technol. 49, 9-14.
20. Kavaler, J., Fu, W., Duan, H., Noll, M. and Posakony, J. W. (1999) An essential role for the Drosophila Pax2 homolog in the differentiation of adult sensory organs. Development 126, 2261-2272.
21. Krauss, S., Johansen, T., Korzh, V. and Fjose, A. (1991). Expression of the zebrafish paired box cene pax[zf-b] during early neurogenesis. Development 113, 1193-1206.
22. Kreidberg, J. A., Sariola, H., Loring, J. M., Maeda, M., Pelletier, J., Housman, D. and Jaenisch, R. (1993). WT-1 is required for early kidney development. Cell 74, 679-691.
23. Lechner, M. S. and Dressler, G. R. (1996). Mapping of Pax-2 transcription activation domains. J. Biol. Chem. 271, 21088-21093.
24. Lechner, M. S. and Dressler, G. R. (1997). The molecular basis of embryonic kidney development. Mech. Dev. 62, 105-120.
25. Liang, D., Xu, X., Chin, A. J., Balasubramaniyan, N. V., Teo, M. A., Lam, T. J., Weinberg, E. S. and Ge, R. (1998). Cloning and characterization of vascular endothelial growth factor (VEGF) from zebrafish, Danio rerio. Biochim. Biophys. Acta 1397, 14-20.
26. Lun, K. and Brand, M. (1998). A series of no isthmus (noi) alleles of the zebrafish pax2.1 gene reveals multiple signaling events in development of the midbrain-hindbrain boundary. Development 125, 3049-3062.
27. Macdonald, R., Barth, K. A., Xu, Q., Holder, N., Mikkola, I. and Wilson, S. W. (1995). Midline signalling is required for Pax gene regulation and patterning of the eyes. Development 121, 3267-3278.
28. Majumdar, A. and Drummond, I. A. (1999). Podocyte differentiation in the absence of endothelial cells as revealed in the zebrafish avascular mutant, cloche. Dev. Genet. 24, 220-229.
29. Marcos-Gutierrez, C. V., Wilson, S. W., Holder, N. and Pachnis, V. (1997). The zebrafish homologue of the ret receptor and its pattern of expression during embryogenesis. Oncogene 14, 879-889.
30. Oxtoby, E. and Jowett, T. (1993). Cloning of the zebratish krox-20 gene (krx-20) and its expression during hindbrain development. Nucleic Acids Res. 21, 1087-1095.
31. Pachnis, V., Mankoo, B. and Costantini, F. (1993). Expression of the c-ret proto-oncogene during mouse embryogenesis. Development 119, 1005-1017.
32. Pelletier, J., Bruening, W., Kashtan, C. E., Mauer, S. M., Manivel, J. C., Striegel, J. E., Houghton, D. C., Junien, C., Habib, R., Fouser, L., et al. (1991). Germline mutations in the Wilms' tumor suppressor gene are associated with abnormal urogenital development in Denys-Drash syndrome. Cell 67, 437-447.
33. Pfeffer, P. L., Gerster, T., Lun, K., Brand, M. and Busslinger, M. (1998). Characterization of three novel members of the zebrafish Pax2/5/8 family: dependency of Pax5 and Pax8 expression on the Pax2.1 (noi) function. Development 125, 3063-3074.
34. Puschel, A. W., Westerfleld, M. and Dressler, G. R. (1992). Comparative analysis of Pax-2 protein distributions during neurulation in mice and zebrafish. Mech. Dev. 38, 197-208.
35. Reifers, F., Bohli, H., Walsh, E. C., Crossley, P. H., Stainier, D. Y. and Brand, M. (1998). Fgf8 is mutated in zebrafish acerebellar (ace) mutants and is required for maintenance of midbrain-hindbrain boundary development and somitogenesis. Development 125, 2381-2395.
36. Rothenpieler, U. W. and Dressler, G. R. (1993). Pax-2 is required for mesenchyme-to-epithelium conversion during kidney development. Development 119, 711-720.
37. Ryan, G., Steele-Perkins, V., Morris, J. F., Rauscher, F. J., 3rd and Dressler, G. R. (1995). Repression of Pax-2 by WT1 during normal kidney development. Development 121, 867-875.
38. Sanyanusin, P., Schimmenti, L. A., McNoe, T. A., Ward, T. A., Pierpont, M. E., Sullivan, M. J., Dobyns, W. B. and Eccles, M. R. (1996) Mutation of the gene in a family with optic nerve colobomas, renal anomolies and vesicoureteral reflux. Nat. Genet. 13, 129.
39. Schuchardt, A., D'Agati, V., Larsson-Blomberg, L., Costanlini, F. and Pachnis, V. (1994). Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret [see comments]. Nature 367, 380-383.
40. Torres, M., Gomez-Pardo, E., Dressler, G. R. and Gruss, P. (1995). Pax-2 controls multiple steps of urogenital development. Development 121, 4057-4065.
41. Toyama, R. and Dawid, I. B. (1997). lim6, a novel LIM homeobox gene in the zebrafish: comparison of its expression pattern with lim1. Dev. Dyn. 209, 406-417.
42. Vize, P. D., Jones, E. A. and Pfister, R. (1995). Development of the Xenopus pronephric system. Dev. Biol. 171, 531-540.
43. Vize, P. D., Seufert, D. W., Carroll, T. J. and Wallingford, J. B. (1997). Model systems for the study of kidney development: use of the pronephros in the analysis of organ induction and patterning. Dev. Biol. 188, 189-204.
44. Wallingford, J. B., Carroll, T. J. and Vize, P. D. (1998). Precocious expression of the Wilms' tumor gene xWT1 inhibits embryonic kidney development in Xenopus laevis. Dev. Biol. 202, 103-112.
45. Westerfield, M. (1993). The Zebrafish Book: a Guide for the Laboratory Use of Zebrafish (Brachydanio rerio). Eugene, OR: M. Westerfield.
46. Yang, Y., Jeanpierre, C., Dressler, G. R., Lacoste, M., Niaudet, P. and Gubler, M. C. (1999). WT1 and PAX-2 podocyte expression in Denys-Drash syndrome and isolated diffuse mesangial sclerosis. Am. J. Pathol. 154, 181-192.