A new method of comprehensive static histomorphometry applied on human lumbar vertebral cancellous bone

Bone

Volumn 27, Issue 1, 2000, Pages 129-138

  Thomsen, J S ^a   Ebbesen, E N ^a   Mosekilde, Li ^a  

^a AARHUS UNIVERSITY   (Denmark)

Author keywords

Aging; Bone structure; Fracture; Histomorphometry; Spine; Vertebral body

Indexed keywords

ADULT; AGED; AGING; ARTICLE; AUTOPSY; BONE STRENGTH; BONE STRUCTURE; CANCELLOUS BONE; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION FUNCTION; FEMALE; HUMAN; HUMAN TISSUE; METHODOLOGY; MORPHOMETRICS; SPINE; VERTEBRA BODY; VERTEBRA FRACTURE; X RAY;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; AGING; FEMALE; HUMANS; IMAGE CYTOMETRY; LUMBAR VERTEBRAE; MALE; MIDDLE AGED; SEX FACTORS;

EID: 0034121111     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/S8756-3282(00)00285-4     Document Type: Article

References (55)

1. Abe K., Mizutani F., Wang C. Thinning of gray-scale images with combined sequential and parallel conditions for pixel removal. IEEE Trans Syst Man Cybern. 24:1994;294-299.
2. Alexiades M.M., Boachie-Adjei O., Vigorita V.J. Histomorphometric analysis of vertebral and iliac crest bone samples. A correlated study. Spine. 15:1990;286-288.
3. Amling M., Grote H.J., Pösl M., Hahn M., Delling G. Polyostotic heterogeneity of the spine in osteoporosis. Quantitative analysis and three-dimensional morphology. Bone Miner. 27:1994;193-208.
4. Amling M., Pösl M., Ritzel H., Hahn M., Vogel M., Wening V.J., Delling G. Architecture and distribution of cancellous bone yield vertebral fracture clues - a histomorphometric analysis of the complete spinal column from 40 autopsy specimens. Arch Orthop Trauma Surg. 115:1996;262-269.
5. Arnold J.S., Bartley M.H., Tont S.A., Jenkins D.P. Skeletal changes in aging and disease. Clin Orthop. 49:1966;17-38.
6. Atkinson P.J. Variation in trabecular structure of vertebrae with age. Calcif Tissue Res. 1:1967;24-32.
7. Bailey, A. J., Sims, T. J., Ebbesen, E. N., Mansell, J. P., Thomsen, J. S., and Mosekilde, Li. Age-related changes in the biochemical properties of human cancellous bone collagen: Relationship to bone strength. Calcif Tissue Int 65:203-210; 1999.
8. Bergot C., Laval-Jeantet A.-M., Prêteux F., Meunier A. Measurement of anisotropic vertebral trabecular bone loss during aging by quantitative image analysis. Calcif Tissue Int. 43:1988;143-149.
9. Bromley R.G., Dockum N.L., Arnold J.S., Jee W.S.S. Quantitative histological study of human lumbar vertebrae. J Gerontol. 21:1966;537-543.
10. Cendre E., Mitton D., Roux J.-P., Arlot M.E., Duboeuf F., Burt-Pichat B., Rumelhart C., Peix G., Meunier P.J. High-resolution computed tomography for architectural characterization of human lumbar cancellous bone Relationships with histomorphometry and biomechanics . Osteopor Int. 10:1999;353-360.
11. Chappard D., Legrand E., Basle M.F., Racineux J.L., Rebel A., Audran M. Altered trabecular architecture induced by corticosteroids A bone histomorphometric study . J Bone Miner Res. 11:1996;676-685.
12. Chappard D., Legrand E., Pascaretti C., Baslé M.F., Audran M. Comparison of eight histomorphometric methods for measuring trabecular bone architecture by image analysis on histological sections. Microsc Res Technol. 45:1999;303-312.
13. Compston J.E., Yamaguchi K., Croucher P.I., Garrahan N.J., Lindsay P.C., Shaw R.W. The effect of gonadotrophin-releasing hormone agonists on iliac crest cancellous bone structure in women with endometriosis. Bone. 16:1995;261-267.
14. Cowin S.C. Wolff's law of trabecular architecture at remodeling equilibrium. J Biomech Eng. 108:1986;83-88.
15. Croucher P.I., Garrahan N.J., Compston J.E. Assessment of cancellous bone structure Comparison of strut analysis, trabecular bone pattern factor, and marrow space star volume . J Bone Miner Res. 11:1996;955-961.
16. Cruz-Orive L.M., Karlsson L.M., Larsen S.E., Wainschtein F. Characterizing anisotropy A new concept . Micron Microsc Acta. 23:1992;75-76.
17. DeHoff R.T., Aigeltinger E.H., Craig K.R. Experimental determination of the topological properties of three-dimensional microstructures. J Microsc. 95:1972;69-91.
18. Dempster D.W., Ferguson-Pell M.W., Mellish R.W.E., Cochran G.V.B., Xie F., Fey C., Horbert W., Parisien M., Lindsay R. Relationships between bone structure in the iliac crest and bone structure and strength in the lumbar spine. Osteopor Int. 3:1993;90-96.
19. Diebold J., Bätge B., Stein H., Müller-Esch G., Müller P.K., Löhrs U. Osteoporosis in longstanding acromegaly Characteristic changes of vertebral trabecular architecture and bone matrix composition . Virchows Arch A Pathol Anat. 419:1991;209-215.
20. Ebbesen E.N., Thomsen J.S., Beck-Nielsen H., Nepper-Rasmussen H.J., Mosekilde Li. Vertebral bone density evaluated by dual-energy x-ray absorptiometry and quantitative computed tomography in vitro. Bone. 23:1998;283-290.
21. Ebbesen E.N., Thomsen J.S., Beck-Nielsen H., Nepper-Rasmussen H.J., Mosekilde Li. Age- and gender-related differences in vertebral bone mass, density, and strength. J Bone Miner Res. 14:1999;1394-1403.
22. Ebbesen E.N., Thomsen J.S., Beck-Nielsen H., Nepper-Rasmussen H.J., Mosekilde Li. Lumbar vertebral body compressive strength evaluated by dual-energy X-ray absorptiometry, quantitative computed tomography, and ashing. Bone. 25:1999;713-724.
23. Ebbesen E.N., Thomsen J.S., Mosekilde Li. Nondestructive determination of iliac crest cancellous bone strength by pQCT. Bone. 21:1997;535-540.
24. Garrahan N.J., Mellish R.W.E., Compston J.E. A new method for the two-dimensional analysis of bone structure in human iliac crest biopsies. J Microsc. 142:1986;341-349.
25. Goulet R.W., Goldstein M.J., Kuhn J.L., Brown M.B., Feldkamp L.A. The relationship between the structural and orthogonal compressive properties of trabecular bone. J Biomech. 27:1994;375-389.
26. Grote H.J., Amling M., Vogel M., Hahn M., Posl M., Delling G. Intervertebral variation in trabecular microarchitecture throughout the normal spine in relation to age. Bone. 16:1995;301-308.
27. Gundersen H.J.G. The nucleator. J Microsc. 151:1988;3-21.
28. Gundersen H.J.G., Boyce R.W., Nyengaard J.R., Odgaard A. The ConnEulor Unbiased estimation of connectivity using physical disector under projection . Bone. 14:1993;217-222.
29. Hahn M., Vogel M., Pompesius-Kempa M., Delling G. Trabecular bone pattern factor - a new parameter for simple quantification of bone microarchitecture. Bone. 13:1992;327-330.
30. Harrigan T.P., Mann R.W. Characterization of microstructural anisotropy in orthotropic materials using a second rank tensor. J Mater Sci. 19:1984;761-767.
31. Kneissel M., Roschger P., Steiner W., Schamall D., Kalchauser G., Boyde A., Teschler-Nicola M. Cancellous bone structure in the growing and aging lumbar spine in a historic nubian population. Calcif Tissue Int. 61:1997;95-100.
32. Lam L., Lee S.-W., Suen C.Y. Thinning methodologies - a comprehensive survey. IEEE Trans Pattern Anal Mach Intell. 14:1992;869-885.
33. Mellish R.W.E., Ferguson-Pell M.W., Cochran G.V.B., Lindsay R., Dempster D.W. A new manual method for assessing two-dimensional cancellous bone structure Comparison between iliac crest and lumbar vertebra . J Bone Miner Res. 6:1991;689-696.
34. Mosekilde Li. Age-related changes in vertebral trabecular bone architecture - assessed by a new method. Bone. 9:1988;247-250.
35. Mosekilde, Li. Sex differences in age-related loss of vertebral trabecular bone mass and structure - biomechanical consequences. Bone 10:425-432; 1989.
36. Mosekilde, Li. Consequences of the remodelling process for vertebral trabecular bone structure: A scanning electron microscopy study (uncoupling of unloaded structures). Bone Miner 10:13-35; 1990.
37. Odgaard A. Three-dimensional methods for quantification of cancellous bone architecture. Bone. 20:1997;315-328.
38. Odgaard A., Jensen E.B., Gundersen H.J.G. Estimation of structural anisotropy based on volume orientation. A new concept. J Microsc. 157:1989;149-162.
39. Odgaard A., Kabel J., van Rietbergen B., Dalstra M., Huiskes R. Fabric and elastic principal directions of cancellous bone are closely related. J Biomech. 30:1997;487-495.
40. Parfitt A.M., Mathews C.H.E., Villanueva A.R., Kleerekoper M., Frame B., Rao D.S. Relationships between surface, volume, and thickness of iliac trabecular bone in aging and osteoporosis Implications for the microanatomic and cellular mechanisms of bone loss . J Clin Invest. 72:1983;1396-1409.
41. Press, W. H., Teukolsky, S. A., Vetterling, W. T., and Flannery, B. P. Numerical Recipes in C - the Art of Scientific Computing, 2nd Ed. Cambridge: Cambridge University; 1992.
42. van Rietbergen B., Odgaard A., Kabel J., Huiskes R. Relationships between bone morphology and bone elastic properties can be accurately quantified using high-resolution computer reconstructions. J Orthop Res. 16:1998;23-28.
43. Ritzel H., Amling M., Vogel M., Pösl M., Hahn M., Werner M., Delling G. Spongiosastruktur und polyostotishe heterogenität bei osteoporose. Pathologe. 17:1996;68-77.
44. Schwartz M.P., Recker R.R. Comparison of surface density and volume of human iliac trabecular bone measured directly and by applied stereology. Calcif Tissue Int. 33:1981;561-565.
45. Smit, T. H. The mechanical significance of the trabecular bone architecture in a human vertebra. Doctoral thesis, Technischen Universität Hamburg-Harburg. Aarchen: Shaker; 1996.
46. Smit T.H., Odgaard A., Schneider E. Structure and function of vertebral trabecular bone. Spine. 22:1997;2823-2833.
47. Smit T.H., Schneider E., Odgaard A. Star length distribution A volume-based concept for the characterization of structural anisotropy . J Microsc. 191:1998;249-257.
48. Sterio D.C. The unbiased estimator of number and sizes of arbitrary particles using the disector. J Microsc. 134:1984;127-136.
49. Thomsen, J. S., Ebbesen, E. N., and Mosekilde, Li. Relationships between static histomorphometry and bone strength measurements in human iliac crest bone biopsies. Bone 22:153-163; 1998.
50. Turner C.H., Cowin S.C., Rho J.Y., Ashman R.B., Rice J.C. The fabric dependence of the orthotropic elastic constants of cancellous bone. J Biomech. 23:1990;549-561.
51. Vesterby A. Star volume of marrow space and trabeculae in iliac crest Sampling procedure and correlation to star volume of first lumbar vertebra . Bone. 11:1990;149-155.
52. Vesterby A., Gundersen H.J.G., Melsen F. Star volume of marrow space and trabeculae of the first lumbar vertebra Sampling efficiency and biological variation . Bone. 10:1989;7-13.
53. Vesterby, A., Mosekilde, Li., Gundersen, H. J. G., Melsen, F., Mosekilde, Le., Holme, K., and Sørensen, S. Biologically meaningful determinants of the in vitro strength of lumbar vertebrae. Bone 12:219-224; 1991.
54. Whitehouse W.J. The quantitative morphology of anisotropic trabecular bone. J Microsc. 101:1974;153-168.
55. Youngs, T. A., Boyce, R. W., Mosekilde, Li., Søgaard, C. H., Paddock, C. L., and Gundersen, H. J. G. Direct stereological estimation of 2D-connectivity in human iliac cancellous bone: The effect of age and sex. Acta Stereol 13:55-60; 1994.