Effects of aniracetam on bladder overactivity in rats with cerebral infarction

Journal of Pharmacology and Experimental Therapeutics

Volumn 293, Issue 3, 2000, Pages 921-928

  Nakada, Yasushi ^a,b   Yokoyama, Osamu ^a   Komatsu, Kazuto ^a   Kodama, Koichi ^a   Yotsuyanagi, Satoshi ^a   Niikura, Susumu ^a   Nagasaka, Yasuhiro ^a   Namiki, Mikio ^a  

^a KANAZAWA UNIV SCHOOL OF MEDICINE   (Japan)

^b TOYAMA CHEMICAL CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANIRACETAM; ATROPINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLADDER CAPACITY; BLADDER FUNCTION; BRAIN INFARCTION; CHOLINERGIC NERVE CELL; CHOLINERGIC SYSTEM; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; FEMALE; NEUROGENIC BLADDER; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ATROPINE; CEREBRAL INFARCTION; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; INJECTIONS, INTRAVENTRICULAR; NEUROPROTECTIVE AGENTS; NOOTROPIC AGENTS; PYRROLIDINONES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, MUSCARINIC; URINARY BLADDER;

EID: 0034119974     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. Cumin R, Bandle EF, Gamzu E and Haefely WE (1982) Effects of novel compound aniracetam (Ro-13-5057) upon impaired learning and memory in rodents. Psychopharmacology 78:104-111.
2. De Groat WC (1998) Anatomy of the central neural pathways controlling the lower urinary tract. Eur Urol 34 (Suppl 1):2-5.
3. 3H]Aniracetam binds to specific recognition sites in brain membranes. J Neurochem 65:912-918.
4. Frostl W and Maitre L (1989) The families of cognition enhancers. Pharmacopsychiatry 22:54-100.
5. Giovannini MG, Rodino P, Mutolo D and Pepeu G (1993) Oxiracetam and aniracetam increase acetylcholine release from the rat hippocampus in vivo. Drug Dev Res 28:503-509.
6. Golanov EV and Reis DJ (1995) Contribution of cerebral edema to the neuronal salvage elicited by stimulation of cerebellar fastigical nucleus after occlusion of the middle cerebral artery in rat. J Cereb Blood Flow Metab 15:172-177.
7. Gouliaev AH and Senning A (1994) Piracetam and other structurally related nootropics. Brain Res Rev 19:180-222.
8. Griffiths DJ, Mccracken PN, Harrison GM, Gormley EA, Moore K, Hooper R, Mcewan AJB and Triscott J (1994) Cerebral aetiology of urinary urge incontinence in elderly people. Age Ageing 23:246-250.
9. Himori N, Suzuki T and Ueno K (1995) Aniracetam, a pyrrolidinone-type cognition enhancer, attenuates the hydroxyl free radical formation in the brain of mice with brain ischemia. J Pharm Pharmacol 47:253-258.
10. Himori N, Watanabe H, Matsuura A, Umeda Y, Kuwahara T, Takemoto C, Takamiya M, Yajima T, Tanaka Y and Nakamura K (1986) General pharmacological properties of aniracetam, a cerebral insufficiency improver. Jpn Pharmacol Ther 14 (Suppl 4):93-128.
11. Ishiura Y (1996) Experimental study of voiding dysfunction induced by cerebral infarction in rats. Jpn J Urol 87:1221-1230.
12. Kitada S, Ikei Y, Hasui Y, Yamaguchi T, Nishi S and Osada Y (1991) Bladder function in elderly males with subclinical MRI lesions. Neurourol Urodyn 10:436-437.
13. Kuji I, Matsuda H, Sumiya H, Taki J, Tsuji S, Kinuya K, Ichikawa A, Shiba K, Mori H and Tonami N (1997) Discrepancy between blood flow and muscarinic receptor distribution in rat brain after middle cerebral artery occlusion. Eur J Nucl Med 24:665-669.
14. Longa EZ, Weinstein PR, Carlson S and Cummins R (1989) Reversible middle cerebral artery occlusion without craniotomy in rats. Stroke 20:84-91.
15. Martin JR and Haefely WE (1993) Pharmacology of aniracetam, a novel pyrrolidinone derivative with cognition enhancing activity. Drug Invest 5 (Suppl 1):4-49.
16. Mizuno H, Komatsu K, Ishiura Y, Yokoyama O and Namiki M (1999) Role of NMDA and AMPA/kainate receptor channels in the prevention of bladder overactivity after cerebral infarction in rats. J Urol 161 (Suppl):45.
17. Nakamura K, Kurasawa M and Tanaka Y (1998) Apomorphine-induced hypoattention in rats and reversal of the choice performance impairment by aniracetam. Eur J Pharmacol 342:127-138.
18. Nakamura Y, Yokoyama O, Komatsu K, Mita E, Namiki M and Kontani H (1999) Effects of nifedipine on bladder overactivity in rats with cerebral infarction. J Urol 162:1502-1507.
19. Niittykoski M, Ruotsalainen S, Haapalinna A, Larson J and Sirviö J (1999) Activation of muscarinic M3-like receptors and β-adrenoceptors, but not M2-like muscarinic receptors or α-adrenoceptors, directly modulates corticostriatal neurotransmission in vitro. Neuroscience 90:95-105.
20. Noto H, Roppolo JR, Steers WD and De Groat WC (1989) Excitatory and inhibitory influences on bladder activity elicited by electrical stimulation in the pontine micturition center in the rat. Brain Res 492:99-115.
21. Otomo E, Hirai S, Hasegawa K, Araki G, Nishimura T and Inanaga K (1987) Usefulness of aniracetam for cerebrovascular disorders: Double-blind trial against Ca hopantenate. J Clin Exp Med (Igaku No Ayumi) 140:989-1016.
22. Otomo E, Hirai S, Terashi A, Hasegawa K, Tazaki Y, Araki G, Itoh E, Nishimura T and Furukawa T (1991) Clinical usefulness of aniracetam for psychiatric symptoms in patients with cerebrovascular disorders: Double-blind trial against placebo. Igaku No Ayumi 156:143-187.
23. Paxinos G and Watson C (1986) The Rat Brain in Stereotaxic Coordinates, 2nd ed., Academic Press, London.
24. Scremin OU and Scremin AME (1986) Physostigmine induced reversal of ischemia following acute mild cerebral artery occlusion in the rat. Stroke 17:1004-1009.
25. Senin U, Parnelti L, Cucinotta D, Criscuolo D, Longo A and Marini G (1993) Clinical experience with aniracetam in the treatment of senile dementia of the Alzheimer's type and related disorders. Drug Invest 5 (Suppl 1):96-105.
26. Spignoli G and Pepeu G (1987) Interactions between oxiracetam, aniracetam and scopolamine on behavior and brain acetylcholine. Pharmacol Biochem Behav 27: 491-495.
27. Tang PC and Ruch TC (1956) Localization of brain stem and diencephalic areas controlling the micturition reflex. J Camp Neurol 106:213-245.
28. Toide K (1989) Effects of aniracetam on one-trial passive avoidance tests and cholinergic neurons in discrete brain regions of rats. Arch Int Pharmacodyn Ther 298:25-37.
29. Tsuchida S, Noto H, Yamaguchi O and Itoh M (1983) Urodynamic studies on hemiplegic patients after cerebrovascular accident. Urology 21:315-318.
30. Ueda T (1998) Improvement of urinary frequency and nocturia by aniracetam in two cases with cerebral infarction. Pharma Medica 16:129-133.
31. Yaksh TL, Durant PAC and Brent CR (1986) Micturition in rats: A chronic model for study of bladder function and effect of anesthetics. Am J Physiol 251:R1177-R1185.
32. Yamamoto T, Koibuchi Y, Miura S, Sawada T, Ozaki R, Esumi K and Ohtsuka M (1995) Effects of vamicamide on urinary bladder functions in conscious dog and rat models of urinary frequency. J Urol 154:2174-2178.
33. Yokoyama O, Ishiura Y, Komatsu K, Mita E, Nakamura Y, Kunimi K, Morikawa K and Namiki M (1998) Effects of MK-801 on bladder overactivity in rats with cerebral infarction. J Urol 159:571-576.
34. Yoshiyama M, Roppolo JR and De Groat WC (1993) Effects of MK-801 on the micturition reflex in the rat-possible sites of action. J Pharmacol Exp Ther 265:844-850.
35. Yoshiyama M, Roppolo JR and De Groat WC (1994) Interactions between glutamatergic and monoaminergic systems controlling the micturition reflex in the ure-thane-anesthetized rat. Brain Res 639:300-308.
36. Yokoyama O, Yoshikawa M, Namiki M and De Groat WC (1999) Glutamatergic and dopaminergic contributions to rat bladder hyperactivity after cerebral artery occlusion. Am J Physiol 276:R935-R942.
37. Yokoyama O, Yoshiyama M, Namiki M and De Groat WC (1997) The influence of anesthesia on bladder hyperactivity induced by middle cerebral artery occlusion in the rat. Am J Physiol 273:R1900-R1907.