Control of thymocyte proliferation via redox-regulated expression of glycolytic genes

Redox Report

Volumn 5, Issue 1, 2000, Pages 52-54

  Brand, Karl ^a,b   Netzker, Roland ^a   Aulwurm, Uwe ^a   Hermfisse, Ulrich ^a   Fabian, Daniela ^a   Weigert, Cora ^a   Schaefer, Doris ^a   Hamm Kuenzelmann, Brigitte ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b Institute of Biochemistry FAU   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON DIOXIDE; DNA; FRUCTOSE BISPHOSPHATE ALDOLASE; GLUCOSE; GLYCOLYTIC ENZYME; HYDROGEN PEROXIDE; LACTIC ACID; LUCIFERASE; PYRUVATE KINASE; WATER;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING SITE; CELL CYCLE S PHASE; CELL PROLIFERATION; CONTROLLED STUDY; ELECTROPHORETIC MOBILITY; ENHANCER REGION; ENZYME ACTIVITY; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GLYCOLYSIS; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROMOTER REGION; RAT; REPORTER GENE; THYMOCYTE; TRANSCRIPTION REGULATION;

ANIMALIA;

EID: 0034119840     PISSN: 13510002     EISSN: None     Source Type: Journal    
DOI: 10.1179/rer.2000.5.1.52     Document Type: Article

References (9)

1. Greiner E, Guppy M, Brand K. Glucose is essential for proliferation and the glycolytic enzyme induction that provokes a transition to glycolytic energy production. J Biol Chem 1994; 269: 31484-31490.
2. Brand KA, Hermfisse U. Aerobic glycolysis by proliferating cells: a protective strategy against reactive oxygen species. FASEB J 1997; 11: 388-395.
3. Brand K. Aerobic glycolysis by proliferating cells: protection against oxidative stress at the expense of energy yield. J Bioenerg Biomembr 1997; 29: 355-364.
4. Brand K, Aichinger S, Forster S et al. Cell-cycle-related metabolic and enzymatic events in proliferating rat thymocytes. Eur J Biochem 1988; 172: 695-702.
5. Netzker R, Greiner E, Eigenbrodt E, Noguchi T, Tanaka T, Brand K. Cell cycle-associated expression of M2-type isozyme of pyruvate kinase in proliferating rat thymocytes. J Biol Chem 1992; 267: 6421-6424.
6. Netzker R, Hermfisse U, Wein KH, Brand K. Expression of glycolytic isozymes in rat thymocytes during cell cycle progression. Biochim Biophys Acta 1994; 1224: 371-376.
7. Hamm-Kuenzelmann B, Schaefer D, Weigert C, Brand K. Redox-regulated expression of glycolytic enzymes in resting and proliferating rat thymocytes. FEBS Lett 1997; 403: 87-90.
8. Schaefer D, Hamm-Kuenzelmann B, Hermfisse U, Brand K. Differences in DNA binding efficiency of Sp1 to aldolase and pyruvate kinase promoter correlate with altered redox states in resting and proliferating rat thymocytes. FEBS Lett 1996; 391: 35-38.
9. Netzker R, Fabian D, Weigert C, Brand KA. Functional studies by site-directed mutagenesis on the role of Sp1 in the expression of the pyruvate kinase M and aldolase A genes. Biochim Biophys Acta 1999; 1444: 231-240.