Urokinase cisternal irrigation therapy for prevention of symptomatic vasospasm after aneurysmal subarachnoid hemorrhage: A study of urokinase concentration and the fibrinolytic system

Stroke

Volumn 31, Issue 6, 2000, Pages 1256-1262

  Sasaki, Tatsuya ^a   Kodama, Namio ^a   Kawakami, Masahisa ^a   Sato, Masahiro ^a   Asari, Jun ^a   Sakurai, Yoshiharu ^b   Watanabe, Kazuo ^c   Onuma, Takehide ^d   Matsuda, Tamotsu ^e  

^a FUKUSHIMA MEDICAL UNIVERSITY   (Japan)

^b SENDAI CITY MEDICAL CENTER   (Japan)

^c S Tohoku Res Inst for Neurosci   (Japan)

^d SENDAI CITY HOSPITAL   (Japan)

^e KANAZAWA UNIVERSITY   (Japan)

Author keywords

Fibrinolysis; Irrigation; Subarachnoid hemorrhage; Urokinase; Vasospasm

Indexed keywords

FIBRIN; FIBRINOLYTIC AGENT; UROKINASE;

ADULT; ARTICLE; BLOOD CLOTTING; BRAIN AQUEDUCT; CEREBROSPINAL FLUID ANALYSIS; CLINICAL ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; FIBRINOLYSIS; HUMAN; PRIORITY JOURNAL; SUBARACHNOID HEMORRHAGE; SURGICAL APPROACH; VASOSPASM;

EID: 0034119087     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.STR.31.6.1256     Document Type: Article

References (20)

1. Dorsch NWC, King MT. A review of cerebral vasospasm in aneurysmal subarachnoid haemorrhage. J Clin Neurosci. 1994;1:19-26.
2. Kodama N, Sasaki T, Kawakami M, Sato M, Asari J. Cisternal irrigation therapy with urokinase and ascorbic acid for prevention of vasospasm after aneurysmal subarachnoid hemorrhage: outcome in 217 patients. Surg Neurol. 2000;53:110-117; discussion 117-118.
3. Findlay JM, Weir BKA, Kassell NF, Disney LB, Grace MGA. Intracisternal recombinant tissue plasminogen activator after aneurysmal subarachnoid hemorrhage. J Neurosurg. 1991;75:181-188.
4. Zabramski JM, Spetzler RF, Lee KS, Papadopoulos SM, Bovill E, Zimmerman RS, Bederson JB. Phase 1 trial of tissue plasminogen activator for the prevention of vasospasm in patients with aneurysmal subarachnoid hemorrhage. J Neurosurg. 1991;75:189-196.
5. Ohman J, Servo A, Heiskanen O. Effect of intrathecal fibrinolytic therapy on clot lysis and vasospasm in patients with aneurysmal subarachnoid hemorrhage. J Neurosurg. 1991;75:197-201.
6. Mizoi K, Yoshimoto T, Fujiwara S, Sugawara T, Takahashi A, Koshu K. Prevention of vasospasm by clot removal and intrathecal bolus injection of tissue-type plasminogen activator: preliminary report. Neurosurgery. 1991;28:807-813.
7. Hariton GB, Findlay JM, Weir BKA, Kasuya H, Grace MGA, Mielke BW. Comparison of intrathecal administration of urokinase and tissue plasminogen activator on subarachnoid clot and chronic vasospasm in a primate model. Neurosurgery. 1993;33:691-697.
8. Mizoi K, Yoshimoto T, Takahashi A, Fujiwara S, Koshu K, Sugawara T. Prospective study on the prevention of cerebral vasospasm by intrathecal fibrinolytic therapy with tissue-type plasminogen activator. J Neurosurg. 1993;78:430-437.
9. Sasaki T, Ohta T, Kikuchi H, Takakura K, Usui M, Ohnishi H, Kondo A. Tanabe H, Nakamura J, Yamada K, Kobayashi N, Ohashi Y. A phase II clinical trial of recombinant tissue-type plasminogen activator against cerebral vasospasm after aneurysmal subarachnoid hemorrhage. Neurosurgery. 1994;35:597-605.
10. Steinberg GK, Vanefsky MC, Marks MP, Adler JR Jr, Koenig GH. Failure of intracisternal tissue plasminogen activator to prevent vasospasm in certain patients with aneurysmal subarachnoid hemorrhage. Neurosurgery. 1994;34:809-814.
11. Usui M, Saito N, Hoya K, Todo T. Vasospasm prevention with postoperative intrathecal thrombolytic therapy: a retrospective comparison of urokinase, tissue plasminogen activator, and cisternal drainage alone. Neurosurgery: 1994;34:235-245.
12. Findlay JM, Kassell NF, Weir BKA, Haley EC Jr, Kongabel G, Germanson T, Truskowski L, Alves WN, Holness RO, Knuckey NW, Yonas H, Steinberg GK, West M, Winn HR, Ferguson G. A randomized trial of intraoperative, intracisternal tissue plasminogen activator for the prevention of vasospasm. Neurosurgery. 1995;37:168-178.
13. Fisher CM, Kistler JR, Davis JM. Relation of cerebral vasospasm to subarachnoid hemorrhage visualized by computerized tomographic scanning. Neurosurgery. 1980;6:1-9.
14. Suzuki J, Komatsu S, Sato T, Sakurai Y. Correlation between CT findings and subsequent development of cerebral infarction due to vasospasm in subarachnoid hemorrhage. Acta Neurochir. 1980;55:63-70.
15. Jennett B, Bond M. Assessment of outcome after severe brain damage: a practical scale. Lancet. 1975;1:480-484.
16. Yoshida Y, Hayashi T, Amoh M, Kusuno K, Uno T, Ogino T, Kobayashi H, Shibata N, Ueki S. Postoperative intrathecal irrigation with plasminogen activator (urokinase) after early stage operation on ruptured cerebral aneurysm [in Japanese with English abstract]. Neurol Med Chir (Tokyo). 1983;23:659-666.
17. Muizelaar JP, Zwienenberg M, Rudidill NA, Hecht ST. The prophylactic use of transluminal balloon angioplasty in patients with Fisher grade 3 subarachnoid hemorrhage: a pilot study. J Neurosurg. 1999;91:51-58.
18. Yamanobe K. Prevention of vasospasm: experimental studies on lysis of the urokinase [in Japanese with English abstract]. Fukushima Med J. 1987;37:27-39.
19. Suzuki M, Kudo A, Otawara Y, Hirashima Y, Takaku A, Ogawa A. Extrinsic pathway of blood coagulation and thrombin in the cerebrospinal fluid after subarachnoid hemorrhage. Neurosurgery. 1999;44:487-494.
20. Ikeda K, Asakura H, Futami K, Yamashita J. Coagulative and fibrinolytic activation in cerebrospinal fluid and plasma after subarachnoid hemorrhage. Neurosurgery. 1997;41:344-350.