Cerebrospinal fluid antibodies directed against neuron-associated gangliosides in HIV-1 infection

Infection

Volumn 28, Issue 3, 2000, Pages 143-148

  Gisslen M ^a   Lekman, A ^a   Fredman, P ^a  

^a SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Anti ganglioside antibodies; Cerebrospinal fluid; HIV 1; Neuron

Indexed keywords

ANTIBODY; GANGLIOSIDE; GANGLIOSIDE GD 1A; GANGLIOSIDE GD 1B; GANGLIOSIDE GM1;

ADULT; ANTIBODY PRODUCTION; ANTIBODY TITER; ARTICLE; ASEPTIC MENINGITIS; CEREBROSPINAL FLUID; CLINICAL ARTICLE; COMPLICATION; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMAN TISSUE; IN VIVO STUDY; MALE; NERVE CELL; NEUROPATHOLOGY; PATHOGENESIS; POLYCLONAL ACTIVATION; SYNAPSE; VIRUS MENINGITIS;

ADULT; ANTIBODIES; AUTOANTIBODIES; ENCEPHALITIS, VIRAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; G(M1) GANGLIOSIDE; GANGLIOSIDES; HIV INFECTIONS; HIV-1; HUMANS; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; LACTONES; MALE; MIDDLE AGED; NEURONS;

EID: 0034116285     PISSN: 03008126     EISSN: None     Source Type: Journal    
DOI: 10.1007/s150100050067     Document Type: Article

References (29)

1. 1. Resnick L, Berger JR, Shapshak P, Tourtellotte WW: Early penetration of the blood-brain-barrier by HIV. Neurology 1988; 38: 9-14.
2. 2. Schacker T, Collier AC, Hughes J, Shea T, Corey L: Clinical and epidemiologic features of primary HIV infection. Ann Intern Med 1996; 125: 257-264.
3. 3. Gisslén M, Hagberg L, Fuchs D, Norkrans G, Svennerholm B: Cerebrospinal fluid viral load in HIV-1-infected patients without antiretroviral treatment: a longitudinal study. J Acquir Immune Defic Syndr Hum Retrovirol 1998; 17: 291-295.
4. 4. Gisslén M, Chiodi F, Fuchs D, Norkrans G, Svennerholm B, Wachter H, Hagberg L: Markers of immune stimulation in the cerebrospinal fluid during HIV infection: a longitudinal study. Scand J Infect Dis 1994; 26: 523-533.
5. 5. Portegies P, Gans de J, Lange J, Derix M, Speelman H, Bakker M, Danner S, Goudsmit J: Declining incidence of AIDS dementia complex after introduction of zidovudine treatment. Br Med J 1989; 299: 819-821.
6. 6. Trujillo JR, Garcia-Ramos G, Novak IS, Rivera VM, Huerta E, Essex M: Neurologic manifestations of AIDS: a comparative study of two populations from Mexico and the United States. J Acquir Immune Defic Syndr Hum Retrovirol 1995; 8: 23-29.
7. 7. Nuovo GJ, Gallery F, MacConnell P, Braun A: In situ detection of polymerase chain reaction-amplified HIV-1 nucleic acids and tumor necrosis factor-alpha RNA in the central nervous system. Am J Pathol 1994; 144: 659-666.
8. 8. Wiley CC, Masliah E, Morey M, Lemere C, DeTeresa R, Grafe M, Hansen L, Terry R: Neocortical damage during HIV infection. Ann Neurol 1991; 29: 651-657.
9. 9. Resnick L, diMarzo-Veronese F, Schupbach J, Tourtellotte WW, Ho DD, Muller F, Shapshak P, Vogt M, Groopman JE, Markham PD: Intra-blood-brain-barrier synthesis of HTLV-III-specific IgG in patients with neurologic symptoms associated with AIDS or AIDS-related complex. N Engl J Med 1985; 313: 1498-1504.
10. 10. Fredman P, Lekman A: Glycosphingolipids as potential diagnostic markers and/or antigens in neurological disorders. Neurochem Res 1997; 22: 1071-1083.
11. 11. Fredman P: The role of anti-glycolipid antibodies in neurological disorders. Ann NY Acad Sci 1998; 845: 341-352.
12. 12. Svennerholm L, Boström K, Fredman P, Månsson J-E, Rosengren B, Rynmark B-M: Human brain gangliosides: developmental changes from early fetal stage to advanced age. Biochim Biophys Acta 1989; 1005: 109-117.
13. 13. CDC: 1993 revised classification system for HIV infection and expanded surveillance case definition for AIDS among adolescents and adults. MMWR Morb Mortal Wkly Rep 1992; 41: RR-17.
14. 14. American Academy of Neurology AIDS Task Force: Nomenclature and research case definitions for neurological manifestations of human immunodeficiency virus-type 1 (HIV-1) infection. Neurology 1991; 41: 778-785.
15. 15. Price RW, Brew BJ: The AIDS dementia complex. J Infect Dis 1988; 158: 1079-1083.
16. 16. Gisslén M, Lekman A, Fredman P: High levels in serum, but no signs of intrathecal synthesis of anti-sulfatide antibodies in HIV-1 infected individuals with or without central nervous system complications. J Neuroimmunol 1999; 94: 153-156.
17. 17. Månsson JE, Fredman P, Bigner DD, Molin K, Rosengren B, Friedman HS, Svennerholm L: Characterization of new gangliosides of the lactotetraose series in murine xenografts of a human glioma cell line. FEBS Lett 1986; 201: 109-113.
18. 3) is a ganglioside of human lung. FEBS Lett 1986; 196: 259-262.
19. 19. Laurell C-B: Quantitative estimation of proteins by electrophoresis in agarose gel containing antibodies. Anal Biochem 1966; 15: 45-52.
20. 20. Tibbling G, Link H, Öhman S: Principles of albumin and IgG analyses in neurological disorders. I. Establishment of reference values. Scand J Clin Lab Invest 1977; 37: 385-390.
21. 21. Wikkelsö C, Andersson M, Andersson R, Blomstrand C: Isoelectric focusing followed by silver staining. A suitable method for routine investigation of cerebrospinal fluid proteins. Eur Neurol 1984; 23: 306-312.
22. 22. Brenneman DE, Westbrook GL, Fitzgerald SP, Ennist DL, Elkins KL, Ruff MR, Pert CB: Neuronal cell killing by the envelope protein of HIV and its prevention by vasoactive intestinal peptide. Nature 1988; 335: 639-642.
23. 23. Achim CL, Heyes MP, Wiley CA: Quantitation of human immunodeficiency virus, immune activation factors, and quinolinic acid in AIDS brains. J Clin Invest 1993; 91: 2769-2775.
24. 24. Hagberg L, Norkrans G, Zanetta JP, Lehmann S, Bergstrom T: Cerebrospinal fluid anti-cerebellar soluble lectin antibodies in human immunodeficiency virus type 1 infection. J Neuroimmunol 1992; 36: 245-249.
25. 25. Mastroianni CM, Liuzzi GM, Vullo V, Jirillo E, Delia S, Riccio P: Detection of cerebrospinal fluid antibodies against myelin basic protein in patients with AIDS dementia complex. Mol Chem Neuropathol 1991; 14: 227-236.
26. 26. Sorice M, Griggi T, Circella A, Nicodemo G, Ciardi M, Mastroianni CM, Lenti L, Sorice F: Cerebrospinal fluid antiganglioside antibodies in patients with AIDS. Infection 1995; 23: 288-291.
27. 27. Gisslén M, Hagberg L, Norkrans G, Lekman A, Fredman P: Increased cerebrospinal fluid ganglioside GM1 concentrations indicating neuronal involvement in all stages of HIV-1 infection. J Neuro Virology 1997; 3: 148-152.
28. 28. Rees JH, Gregson NA, Hughes RA: Anti-ganglioside GM1 antibodies in Guillain-Barré syndrome and their relationship to Campylobacter jejuni infection. Ann Neurol 1995; 38: 809-816.
29. 29. Biessels GJ, Franssen H, van den Berg LH, Gibson A, Kappelle LJ, Venables GS, Wokke JH: Multifocal motor neuropathy. J Neurol 1997; 244: 143-152.