Microwave heating in organic synthesis: Decarboxylation of malonic acid derivatives in water

Synthetic Communications

Volumn 30, Issue 12, 2000, Pages 2099-2104

  Zara, Cynthia Lynn ^a   Jin, Thomas ^a   Giguere, Raymond J ^a  

^a SKIDMORE COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ESTER; MALONIC ACID; SORBIC ACID; WATER;

ARTICLE; AUTOCLAVE; CHEMICAL REACTION; DECARBOXYLATION; MICROWAVE COOKING; REACTION ANALYSIS; SYNTHESIS; TEMPERATURE;

EID: 0034115796     PISSN: 00397911     EISSN: None     Source Type: Journal    
DOI: 10.1080/00397910008087388     Document Type: Article

References (16)

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2. A number of commercial manufacturers provide laboratory scale microwave reactors as well as pilot scale designs for industrial needs. Milestone, Inc. of Monroe, CT, Lambda Technologies of Raleigh, NC, Cober Electronics, Inc. of S. Norwalk, CT and CEM of TN are a few examples.
3. a) R. J. Giguere in Organic Synthesis: Theory and Applications. Vol. 1. edited by Tomas Hudlicky, JAI Press, Greenwich, CT, 1989 , 103-172.
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9. g) Majetich, G.F., Wheless, K. in Microwave-Enhanced Chemistry, ACS Publications, 1997, 455-505 (This last review documents microwave work prior to Spring, 1993).
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12. The Ethos microwave reactor is produced by Milestone, Inc., 160B Shelton Road, Monroe, CT. 06408.
13. rd Microwave Power Symposium, Chicago, July 12-15, 1998.
14. For related work on decarboxylations of organic compounds using microwaves, see: a) Loupy, A., Pigeon, P., Ramdani, M., Jacquault, P. J. Chem. Research(S) 1993, 36.
15. b) Jones, G.B., Chapman, B.J. J. Org. Chem. 1993 58, 5558. For other microwave organic reactions conducted in water, confer Ref. 3f above, pp. 1684-1687.
16. Weflon is a patented Milestone telfon polymer loaded with particulite carbon that facilitates its coupling with microwaves.